San Francisco Giants vs Pittsburgh Pirates Odds, Picks & Player Props (Aug 6)

• The San Francisco Giants are road favorites, leaning on ace Robbie Ray to secure a series victory against the Pittsburgh Pirates.
• The total is set at 8.0 runs, with strong betting trends and public action pointing towards the Over.
• Key player props focus on Giants starter Robbie Ray’s strikeouts and the offensive production of Willy Adames and Bryan Reynolds.

The San Francisco Giants (57-57) visit the Pittsburgh Pirates (49-65) in the finale of a three-game series at PNC Park on Wednesday afternoon with first pitch scheduled for 12:35 pm ET. The pitching matchup features two left-handers, with Robbie Ray (9-5, 2.85 ERA) getting the ball for the visitors against Andrew Heaney (5-9, 4.89 ERA) for the home team.

The Giants are already in desperation mode, sitting six games out of the final Wild Card in the NL. While the Giants have a clear advantage on the mound, the Pirates have been surprisingly resilient as underdogs recently. This article will break down the Giants vs Pirates odds, analyze key player props, and provide our best bets for this National League showdown.

Jump to: Odds | Pitcher-vs-Batter History | Player Props | Predictions

Giants vs Pirates Odds

Odds as of August 6, 2025, from MGM.

The Giants have been established as -143 road favorites, largely due to the significant disparity in the starting pitching matchup. The Pirates are positioned as +118 home underdogs in Wednesday’s MLB odds. The runline has inverse odds, with San Francisco at +118 to win by two or more and Pittsburgh at -143 to keep the score within a run.The total of 8.0 runs is accompanied by slightly heavier odds on the Over, suggesting oddsmakers anticipate a decent amount of offense despite the pitcher-friendly reputation of PNC Park.

Vig-free implied win probability: San Francisco Giants 56.2%, Pittsburgh Pirates 43.8%.

SFG vs PIT Odds Movement

The betting market has seen some intriguing shifts ahead of this contest. The Giants opened as -149 favorites, but their moneyline has faded to -143, a slight six-cent shift toward the Pirates. This is noteworthy because the MLB public betting splits show overwhelming support for the Giants, with 76% of bets and a staggering 95% of the money backing the road team. This reverse line movement suggests that some sharp, respected bettors may be taking a position on the underdog Pirates, causing the books to adjust the price against the public tide.

The total has held steady at 8.0 runs, but the juice has flipped. It opened with the under favored at -115, but has since moved to favor the over at -115. This adjustment is a direct response to betting volume, as 88% of tickets and 90% of the handle are on the over. With no significant injury news or weather changes driving the movement, it appears the market is reacting to recent high-scoring trends for both clubs.

Starting Pitcher-vs-Batter History

Though both pitchers have ten-plus years of experience, there isn’t a ton of history against the lineups they’ll see on Wednesday afternoon. What history does exist clearly favors the batters, especially on the San Francisco bench.

Giants Batters vs Andrew Heaney (LHP)

Only five Giants have faced Heaney more than twice, but three of the five have absolutely murdered the Pittsburgh lefty. Wilmer Flores (.471 average, 1.221 OPS) has been particularly good against Heaney in a fairly big sample size.

On the whole, the Giants’ lineup features several right-handed power threats who have historically performed well against left-handed pitching. Heaney relies primarily on a fastball-slider combination but has been susceptible to the home-run ball this season, posting a 4.89 ERA. His command has wavered in recent starts, and a patient Giants lineup could force him into high-pitch counts and take advantage of mistakes over the heart of the plate.

Pirates Batters vs Robbie Ray (LHP)

The few Pirates who have seen Ray before also have excellent numbers, though much of that stems from years ago while Ray was with the Diamondbacks (2015-2020) before spending half-a-decade in the AL. Andrew McCutchen is the only Pirate with a home run off of Ray.

Ray presents a formidable challenge with his high-velocity fastball and devastating slider, a combination that has propelled him to a 2.85 ERA. The Pirates lineup, which includes key left-handed bats like Oneil Cruz, will be tested. While Cruz possesses immense power, he is also prone to strikeouts, a tendency Ray excels at exploiting.

For Pittsburgh to find success, hitters like Bryan Reynolds and Nick Gonzales will need to work counts and capitalize on the few mistakes Ray makes. The Pirates’ overall offensive struggles suggest they will have a difficult time generating sustained rallies against a pitcher of Ray’s caliber.

Giants vs Pirates Player Props

MLB player props represent the consensus lines as of 10:01 am ET, August 6.

Ray’s strikeout line of 6.5 is a focal point. Given his high K-rate and the Pirates’ susceptibility to swings and misses, the over (-128) is an attractive play. His earned-runs prop at 2.5 with heavy juice on the under (-161) reflects the market’s confidence in him delivering a quality start.

Conversely, Heaney’s strikeout prop is set at a very low 3.5. While the over is favored, his recent performances makes this a risky bet. The value may lie in taking the over on his 2.5 earned runs allowed at +105, banking on the powerful Giants lineup to get to him early.

San Francisco Giants vs Pittsburgh Pirates Picks & Prediction

The core of this handicap lies in the massive pitching mismatch. Ray has been a model of consistency, posting a dominant 2.85 ERA with a high strikeout rate. He steps onto the mound against a Pirates team that, despite a recent 7-3 run, has struggled offensively for most of the season. On the other side, Pirates starter Andrew Heaney has been trending in the wrong direction, with his ERA ballooning to 4.89 after a brutal stretch in July where he posted a 9.00 ERA. Heaney has been vulnerable to power, a strength of the Giants’ lineup with bats like Willy Adames and Matt Chapman.

While the pitching duel heavily favors the Giants, several betting trends add layers to this matchup. The Over has been a consistent winner, hitting in eight of the Giants’ last 10 road games and in seven of the Pirates’ last 10 games as a home underdog. Furthermore, the Over is 6-2 in the last eight head-to-head meetings between these clubs. However, a powerful trend against San Francisco is their poor performance on the road after a win, where they are just 6-14 (.300) in their last 20 such games.

Despite the concerning road trend and some reverse line movement, the on-field fundamentals are too strong to ignore. Ray should be able to neutralize the Pirates’ key bats, while the Giants’ offense is poised to take advantage of Heaney’s struggles. The public is heavily backing the Giants, but in this case, they appear to be on the right side. The best value lies in taking the Giants to win by multiple runs.

Picks:

• San Francisco Giants moneyline (-143)
• Over 8.0 runs (-115)
• Robbie Ray over 6.5 strikeouts (-128)

PIT vs SFG Public-Betting Splits

Public betting data reflects overwhelming support for the San Francisco Giants on both the moneyline and run line, as well as a heavy lean on the over. The significant discrepancy between bet percentage and money percentage on the Giants moneyline indicates that large, confident wagers are backing the road favorites.