Philadelphia Eagles vs New York Giants Picks, Predictions, Player Props & Odds

• The Eagles are heavy 7.5-point road favorites in a Thursday Night Football divisional clash with the New York Giants.
• Star running back Saquon Barkley makes his highly anticipated return to MetLife Stadium to face his former team for the first time.
• This article breaks down the key matchups, analyzes player props, and provides data-driven predictions for this NFC East showdown.

The NFC East-leading Philadelphia Eagles (4-1, 3-2 ATS, 2-3 O/U) travel to face the cellar-dwelling New York Giants (1-4, 2-3 ATS, 1-4 O/U) in a Thursday Night Football mismatch in Week 6. The Eagles and Giants kickoff from MetLife Stadium in East Rutherford, NJ, at 8:15 pm ET on October 9th. Amazon Prime Video will have the broadcast and the weather forecast calls for a clear evening with temperatures around 57°F and minimal wind.

Despite losing their first game of the season last week, the Eagles are big road favorites on TNF, laying 7.5 points at most sportsbooks.

Saquon Barkley torched his former team the first time he returned to MetLife in Week 7 last year, piling up 176 rushing yards and a TD on just 17 carries in a lopsided 28-3 win. After a quiet start to the season (267 rush yards in five games), is the 2018 second-overall pick poised for another monster night against his old team?

Below, I have set out my favorite Eagles vs Giants picks and predictions, the main PHI/NYG player props, and lastly the updated TNF odds.

Philadelphia Eagles vs New York Giants Picks & Expert Prediction

• Philadelphia Eagles -7.0 (-105)
• Under 40.5 (-105)
• Saquon Barkley anytime TD Scorer (-145)

New York’s 21-18 Week 4 win over the Chargers, in Jaxson Dart’s first start no less, led to short-lived optimism in the Big Apple. The entire team, rookie QB included, laid an absolute egg against previously-winless New Orleans in Week 5, falling 26-14 as 1.5-point road favorites.

Now they face an Eagles that has owned them of late. Philly won both games last year, including a 2013 Week 18 victory in which the bulk of their starters were resting up for the postseason.

The biggest factor in this game will be the battle in the trenches, an area where the Eagles hold a monumental advantage. The Giants’ offensive line has been porous, allowing consistent pressure on their QBs. Against an Eagles defense that excels at getting to the quarterback, expect a long night for the Giants’ offense.

On the other side of the ball, Jalen Hurts and the Eagles’ offense should be able to impose their will. Saquon Barkley was obviously geared up for his first game against his old team last year, and he’ll get to feat on a Giants defense that ranks 26th in the league against the run.

Plenty of betting trends also favor Philadelphia on TNF. The Eagles are 7-1 ATS in their last eight road games and 9-1 straight up in their last 10 games as a favorite, the lone ATS loss in that span coming last week in a disappointing 21-17 home loss to Denver.

The Giants are on the opposite end of that spectrum, with a dismal 2-15 record in their last 17 games and an even worse 1-9 record in their last 10 primetime appearances.

Given the overwhelming statistical mismatches and powerful betting trends, laying the points with the road favorite is the play. The Giants have failed to cover in 13 of their last 17 games, and there’s little reason to believe that trend will reverse against the class of the division.

Philadelphia Eagles vs New York Player Props

NFL player props as of October 8, 2025 from FanDuel.

Saquon Barkley’s props are the most intriguing. His rushing total of 85.5 yards is ambitious, but against a Giants defense allowing 140 yards per game, it’s certainly achievable in a revenge-game narrative. In my view, the best value on the board is his anytime touchdown scorer prop at -145.

For the Giants, Wan’dale Robinson’s reception line of 5.5 seems high for an offense that struggles to sustain drives, making the under an attractive play.

Philadelphia Eagles vs New York Giants Odds

As of mid-day Wednesday, the Eagles/Giants point spread ranged from PHI -7.0 to -7.5. If you want to bet the Eagles at the lower number, you’ll have to stomach -120 juice. If you want to back the Giants at the higher number, you won’t do better than -114 at the moment. On the moneyline, New York is as long as +310. The best moneyline price on the Eagles is currently -380.

The total shows a half-point discrepancy from book to book. Over bettors can get 40.5 (-108) at DraftKings. Under bettors should take 41.0 (-110) at BetMGM.

Odds commentary as of 1:59 pm ET, Oct. 8. The odds in the table will update automatically with the best available price for each market if the lines move before kickoff.

NYG vs PHI Odds Movement

The spread has only moved a touch since opening at PHI -7.0. The moneyline has also been relatively static after opening at -360/+285 in Philly’s favor.

The total, however, has come way down from the opening 42.5-point O/U. The NFL public betting splits for TNF show 69% of handle on the under on just 55% of bets, indicating it could be dropping even further before kickoff on Thursday night.