Michigan vs Indiana Odds, Lines and Picks

• The 4th-ranked Michigan Wolverines visit the Indiana Hoosiers on Saturday, October 8
• Michigan is one of two schools to rank in top-6 scoring offense and defense
• See below for odds, analysis and our betting prediction

Though they’ve got far bigger goals in mind, a Michigan Wolverines win Saturday (October 8) over the Indiana Hoosiers, and they’ve booked their bowl eligibility for this season.

Another loss for Indiana, and it’s likely their bowl dreams end after Week 6.

The 4th-ranked Wolverines have started hot this year, ripping off five straight wins, and are on course for a spot on the College Football Playoff.

They’ll be monster 21.5-point favorites when things kick off at 12pm ET from Memorial Stadium. The game can be seen live on FOX.

Michigan vs Indiana Odds

Odds as of October 4 from Barstool Sporstbook. 

The latest college football odds have the host Hoosiers as distant +1000 ‘dogs on the moneyline, in a game that has a total of 59.

Weather shouldn’t be a factor Saturday, with scattered sun and cloud and 60-degree weather.

Wolverines’ Betting Outlook

After putting up better than 50+ points in each of their first three games, Michigan has cooled off slightly. They had their closest win of the season in Week 4, getting by Maryland 34-27.

Last week, they raced out to a 20-0 lead before two late scores allowed made it a more reasonable 27-14 win over Iowa.

One more thing:

31 on Iowa just so happens to be stud LB Jack Campbell. 😱@blake_corum x @UMichFootball pic.twitter.com/WtJhTf6hlb

— Michigan On BTN (@MichiganOnBTN) October 1, 2022

A talented Iowa D, which came into the game leading the nation in scoring defense, sixth in total defense and rushing defense was punctured early by Michigan. They finished with 172 rush yards and 327 total yards, while scoring on four of their first five possessions to take control.

Blake Corum was at the center of it all, carrying 29 times for 133 yards and a touchdown. Michigan is 13th in the country in rushing offense, churning out nearly 222 yards per game.

Not the first TD Donovan Edwards has scored vs. Iowa. 😏 @DEdwards__ x @UMichFootball pic.twitter.com/LnkQmsQgqi

— Michigan On BTN (@MichiganOnBTN) October 1, 2022

JJ McCarthy was 18-for-24 passing for 155 yards and a TD pass to Donovan Edwards.

The defense did a lot of heavy lifting in this one, holding the Hawkeyes’ rush attack to 35 yards on 24 carries.

Heading into this week, Michigan and Alabama were the only schools to rank in the top six of both scoring offense and defense in the NCAA.

Hoosiers’ Betting Outlook

After starting the year with three straight wins, the Indiana Hoosiers have crashed back down to earth with two straight losses. Their latest was a crushing 35-21 loss at the hands of the Nebraska Cornhuskers. Coming into the game, Nebraska had lost nine straight to FBS opponents.

💣s away!!!!@treythekiid3's HUGE catch puts @HuskerFBNation back on top! pic.twitter.com/P0EejtNx6W

— FOX College Football (@CFBONFOX) October 2, 2022

After falling behind 14-0, Indiana did work their way back to 21-21 tie, before giving up 14 fourth-quarter points, including a 71-yard catch and run score by Trey Palmer to give Nebraska the lead for good.

IU’s defense will easily face its toughest test of the year, and they’re already 107th in total yards allowed, with teams racking up 420.4 yards per game, and 5.45 yards per play.

Indiana head coach Tom Allen on Inside Indiana Football, speaking on Connor Bazelak:

“He’s been solid, but he needs to be better.” #iufb

— Mason Williams (@mvsonwilliams) September 28, 2022

One strength that could potentially help cover this large spread is the passing attack, which ranks 33rd in the nation, averaging 278.8 yards per game, and a healthy 10.72 yards per completion.

Connor Bazelak threw for 223 yards and a TD against Nebraska. He’s thrown eight TD’s on the year, but does have five interceptions.

Michigan vs Indiana Pick

Wins by Indiana in this head-to-head are few and far between. They have just a one win against Michigan since 1987, and it came in the COVID-shortened 2020 campaign.

Michigan is used to these big lines, they’re 2-1 against the spread when being favored by 21 or more this season. They’re also 4-0 ATS in their last four games on the road, and 6-1 ATS in their last seven conference games.

Indiana is just 1-7 ATS in their last eight home games, and 0-4 ATS in their last four home games against teams with winning road records.

Look for the Wolverines to get out early and leave no doubt against the 2nd-worst scoring defense in the Big Ten.

The Pick:

• Michigan -21.5 (-109); 1 unit to win 0.92 units
• Week 5 NCAAF Record: 2-0: Overall: 3-2 ATS, 1-0 o/u; +1.64 units