Manchester United vs Atletico Madrid Odds & Prediction – Champions League Round of 16 Leg 2

By John Dillon in Soccer News
Updated: October 27, 2022 at 4:07 am EDTPublished:

- English giant United hosts reigning Spanish champion at Old Trafford on Tuesday at 4:00 pm ET
- The tie is finely balanced after a tight 1-1 draw in the first leg at the Wanda Metropolitano
- See the odds & best bets for Manchester United vs Atletico Madrid in the Champions League Round of 16 Leg 2
Manchester United will be hoping for more heroics from its superstar forward Cristiano Ronaldo when Atletico Madrid visit Old Trafford in the Champions League on Tuesday.
The last 16 tie is delicately poised after a 1-1 draw in the first leg in Spain.
However, United has been given a huge boost to its confidence by the stunning return to form of Ronaldo.
He scored a hat-trick in the 3-2 defeat of Tottenham Hotspur in Manchester last Saturday.
Manchester United vs Atletico Madrid Odds
Matchup | Spread | Moneyline | Total |
---|---|---|---|
Man. Utd vs Atletico Madrid | MAN -0.5 (+123) | ATL +0.5 (-148) | MAN +125 | ATL +245 | DRAW +225 | Ov 2.5 (+133) | Un 2.5 (-165) |
Odds as of March 14 at Barstool

Bet $1 & Double Your Winnings On Your First 20 Wagers!
That has, furthermore, helped make United the favorite for a win against the Spanish champions, although the odds suggest it could be a close, low-scoring affair
At Barstool Sportsbook, United is accordingly priced at +125 for a home victory in the game which kicks off at 4:00 pm ET.
https://youtu.be/ANJDYeUB7Mc
Meanwhile, Atletico is priced at +245 with the draw after 90 minutes at +225.
The odds for Ronaldo to get on the scoresheet again are quite decent at +163. Additionally, the price is an inviting +420 for Ronaldo to score first.
Six Goals In Europe for Ronaldo
He has hit the target six times in six European appearances for the team this season.
Moreover, he has scored no fewer than 25 times against Atletico during his career.
Cristiano Ronaldo has long been a thorn in Diego Simeone's Atletico side 😤
With Man Utd's return #UCL fixture in the balance this week, who's to say he won't produce once again… 🔮pic.twitter.com/40hfBnQOEs
— Football on TNT Sports (@footballontnt) March 14, 2022
It is only against Sevilla that he has scored more during his spells with Sporting Lisbon, United, Real Madrid and Juventus.
Meanwhile, it is Atletico which is currently displaying the better domestic form.
Its 2-1 defeat of Cadiz in Madrid last Friday emphatically made it four league wins in succession.
This, consequently, places it fourth in La Liga.
United, meanwhile, has been lifted by the defeat of Spurs. But, previously, it had suffered a 4-1 humiliation in the derby against Manchester City.

Before that, it had also endured a lot of criticism following a dull 0-0 draw at home against struggling Watford.
Therefore, it is presently in fifth place in the Premier League.
This competition chiefly offers both teams their only hope of lifting silverware this season. However, neither is among the favorites in the Champions League odds.
During the first leg at the Wanda Metropolitano Stadium, Joao Felix gave Atletico a first-half lead.
Elanga’s Late Equalizer In Madrid
But United equalized 10 minutes from the end through Anthony Elanga.
There was certainly more possession for United at 61-percent against Atletico, with 39-percent.
This could be a huge blow for Man Utd!
Bruno Fernandes set to miss Atletico Madrid clash after catching Covid and missing Tottenham win https://t.co/FiQUd5mMOt
— The Sun Football ⚽ (@TheSunFootball) March 14, 2022
But the Spanish side comparatively managed more goal attempts – with 11 to United’s seven.
Diego Simeone’s Atletico side was, furthermore, credited with 43 dangerous attacks compared with 29 for United.
However, those possession stats suggest that Atletico was typically happy to allow United to have the ball.
And that certainly makes it likely it will play it cagily and stay behind the ball in the return at Old Trafford – in keeping with Simeone’s famed defensive style.
Before the first leg meeting, these teams had clashed only twice before in European competition.
https://youtu.be/uTTkarpVsKY
In the 1991-92 European Cup Winners Cup, they met at the second round stage.
Atletico was a 3-0 winner at home before a 1-1 draw in Manchester handed the Spanish side a 4-1 aggregate victory.
In the group stage this season, United won its section ahead of Villa real, Atalanta and Switzerland’s Young Boys.
Man United midfielder Paul Pogba sends message to Atletico Madrid
Man Utd welcome Atletico Madrid to Old Trafford on Tuesday for the second leg of their last-16 Champions League tie.https://t.co/wgbT9ZSr09— SHEVCHENKO 𓃵K.CHESANG (@SOEKOCCESS) March 14, 2022
However, its record was patchy, with three wins, two draws and one defeat – firstly in the opening game against Young Boys.
Atletico was second behind Liverpool in its group – winning only twice in the section while drawing once and losing three times.
However, an impressive 3-1 win away at Porto in the final game eventually clinched its qualification for the knockout phase.
Manchester United vs Atletico Madrid Stats
3 | Wins | 2 |
3 | Draws | 2 |
1 | Losses | 3 |
12 | Goals | 8 |
9 | Goals Against | 9 |
5 | Yellow Cards | 4 |
0 | Red Cards | 0 |
1 | Clean Sheets | 1 |
*Stats from UCL 2021-22.
Home advantage could certainly help United here as it is unbeaten in its last four fixtures at its HQ.
Furthermore, Atletico has kept only one clean sheet in its last five away fixtures.
Straight Knockout Occassion
With away goals no longer counting double, meanwhile, the 1-1 first leg draw makes the return a straight knockout occasion.
There will subsequently be extra time and penalties if things are still level after 90 minutes.
United could be without Portuguese craftsman Bruno Fernandes, who missed the Tottenham game through illness.
Ralf Rangnick is set to unleash a brilliant Man Utd double act for Atletico Madrid clash: MANCHESTER UNITED go up against Atletico Madrid in the Champions League on Tuesday night. https://t.co/GyyERdDeqx pic.twitter.com/VwPeNobJxZ
— Atleti_MP (@Atleti_MP) March 14, 2022
Angel Correa, Atletico’s Argentine midfielder, is also a doubt.
However, this may well be a night dominated by the brilliant Ronaldo.
So, to sum, up, a United win undoubtedly looks likely – and there is a good chance Ronaldo will be the first player to hit the target this time around.
Pick: Cristiano Ronaldo – First Goalscorer (+420)
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Sports Writer
John Dillon is a leading member of the UK's sporting media, having spent three decades as a national newspaper soccer and sports writer, broadcaster and author. He has covered five World Cups, six European Championships and was Chief Sports Writer at the Daily Express for 14 years.