Giants vs Cardinals Picks, Odds & Starting Pitchers (June 12)

By Chris Amberley in MLB Baseball
Published:

- The Giants vs Cardinals odds list San Fran as -130 moneyline favorites on Monday
- St. Louis enters play losers of nine of their past 12 games
- Keep reading for the latest Giants vs Cardinals picks, odds, and starting pitchers
Fresh off a third straight series loss, the Cardinals (27-39, 13-18 home) open up a new three-game set on Monday versus the Giants (33-32, 15-15 away).
St. Louis has dropped seven of its last nine outings, and nine of 12 overall, and online sportsbooks expect their struggles to continue versus San Fran. They opened up the Giants as the road chalk in the MLB odds, as San Francisco aims for a fifth win in seven games.
Giants vs Cardinals Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
San Francisco Giants | -130 | -1.5 (+125) | O 8 (-115) |
St. Louis Cardinals | +110 | +1.5 (-150) | U 8 (-105) |
The Giants are currently -130 moneyline favorites, in a contest with a total of 8. First pitch is scheduled for 7:45 pm ET at Busch Stadium in St. Louis, Missouri, with clear skies and 70 degree temperatures on deck.

SPORTSBOOK
Odds as of June 11 at Bet365. Check out SBD’s Bet365 review or another one of North America’s online sports betting sites.
San Francisco vs St. Louis Probable Pitchers
You have to scroll pretty far down the list in the World Series odds to find either one of these teams, but shockingly the Cardinals boast a shorter championship price despite miserable form and a worse record than San Fran.
The Giants will give the ball to ace Logan Webb on Monday, as he looks to bounce back from a rough start to the month. Webb has coughed up 12 hits and seven runs in 12.1 innings so far in June, after posting a sparkling 1.30 ERA in May.
Logan Webb's 2Ks in the 3rd. pic.twitter.com/oeC7FUEz4G
— Rob Friedman (@PitchingNinja) June 3, 2023
Prior to this month, he’d surrendered two or fewer runs in seven straight starts, a stretch that includes a date with St. Louis.
Webb held the Cardinals regulars in the MLB starting lineups to two runs over 6.2 innings back in late April, while striking out seven. He’s faced current St. Louis batters 70 times throughout his career, limiting them to four extra-base hits, while striking out 16.
Webb vs Liberatore Stats
4-6 | Record | 1-2 |
3.09 | ERA | 6.00 |
1.09 | WHIP | 1.60 |
.239 | OBA | .271 |
5.0 | SO/W Ratio | 1.4 |
The Cards will counter with Matthew Liberatore, which is good news for the Giants bats. The 23-year-old has been roughed up in back-to-back starts, which continues the trend he started in his rookie campaign last year.
Through 10 career starts, Liberator has an ERA of 6.00. He’s allowing more than a walk every two innings, while opponents are slashing .271/.366/.407 against him.
Last time out, Liberatore got roughed up by the Rangers, lasting only 4.0 innings. He yielded seven hits, five runs and a homer to Texas, after allowing four runs in 5 innings versus the lowly Guardians in his previous outing.
Giants vs Cardinals Predictions
The San Fran bats have been hot and cold lately, but when they’re dialed in look out. The Giants pounded 15 hits and crossed the plate 13 times in a win over Chicago on Sunday, marking the second time in the last week they’ve scored double-digit runs.
Both Joc Pederson and Thairo Estrada clubbed two homers versus the Cubs, with Pederson recording a perfect 4-for-4 afternoon. That marked the second time this weekend he racked up four hits, and he’s batting .454 over the last eight days.
The outlook for the Cardinals offense doesn’t look nearly as optimistic. St. Louis is slashing .216/.286/.392 over the last week, averaging only three runs per game.
The Cardinals are one of the five worst teams in baseball 😬
St. Louis hasn't had a losing season since 2007 😳#STLCards | #MLB pic.twitter.com/YOEqzbAywb
— FanDuel (@FanDuel) June 11, 2023
They went 1-for-11 with runners in scoring position in a 4-3 defeat on Sunday, and are batting .129 (9-for-70) in that scenario over the last 12 games. They’re a dreadful 7-15 in one run games and currently occupy the NL Central cellar.
Giants vs Cardinals 2023 H2H Results
Date | Away Team | Home Team | Result |
---|---|---|---|
April 27 | Cardinals | Giants | STL, 6-0 |
April 26 | Cardinals | Giants | SF, 7-3 |
April 25 | Cardinals | Giants | SF, 5-4 |
April 24 | Cardinals | Giants | SF, 4-0 |
The Cardinals haven’t had a losing season since 2007, and haven’t finished last in their division since 1990. They’re getting meaningful contributions from Paul Goldschmidt, Nolan Arenado and Nolan Gorman, but the rest of the roster has been a major disappointment.
No other St. Louis regular has a batting average north of .253, or a WAR above 0.8. They’re now 12 games under .500 for the season, and haven’t won a series since early May. They’ve dropped three of their first four matchups with San Francisco this year, averaging only 3.2 runs per game.
Pick: San Francisco Giants Moneyline (-130)

Sports Writer
As SBD's resident Swiss Army Knife, Chris covers virtually every sport including NFL, PGA, NBA, MLB, NCAAB, NCAAF and the Olympics. A true grinder, he'd rather pick off small edges in the player props market than swing for the fences with a 5-leg parlay.