Los Angeles Rams vs Tennessee Titans Odds, Injuries, Player Props & Picks

• The Los Angeles Rams are 5.5-point road favorites against the Tennessee Titans in Week 2
• The Rams are 6-0 ATS in their last six road games, while the Titans are 0-8 ATS in their last eight home games
• See the latest Rams vs Titans odds, picks, predictions, and player props to bet on Sep. 14

A Week 2 inter-conference clash features two teams on opposite trajectories as the contending Los Angeles Rams (1-0, 0-0 away, 1-0 ATS, 0-1 O/U) visit the rebuilding Tennessee Titans (0-1, 0-0 home, 0-1 ATS, 0-1 O/U) at Nissan Stadium at 12:00 pm CT/1:00 pm ET.

Led by veteran quarterback Matthew Stafford, who just surpassed 60,000 passing yards, the Rams are looking to build on a solid Week 1 victory over Houston (14-9). Rookie quarterback Cam Ward showed poise in Tennessee’s 20-12 Week 1 loss at Denver, but drives frequently sputtered behind a porous offensive line that allowed six sacks.

Now facing a formidable Rams defensive front, Ward and the Titans face an uphill battle to avoid an 0-2 start and end a seven-game losing streak that extends back to last season. Below, I will break down the odds and key matchups, before setting out the Rams/Titans player props and my picks for the game.

LA Rams vs TEN Titans Odds

Roughly three hours from kickoff, the Rams are 5.5-point chalk and -245 (or shorter) on the moneyline. The Titans are as long as +210 on the moneyline, a significant drop from their opening price of +176. The total is sitting at 41.5, a one-point decline from the opening O/U of 42.5. The NFL over/under trends show that both teams stayed well under their totals in Week 1.

The Rams have been a covering machine lately, boasting an 8-1 ATS record in their last nine games and a perfect 6-0 ATS mark in their last six on the road. Conversely, the Titans have been a bettor’s nightmare, especially at home where they have failed to cover in eight straight contests. The total is a major talking point, dropping a full point from its opening number, a move likely influenced by Tennessee’s anemic offensive output in Week 1 (12 points) and injury concerns on both offensive lines.

LAR vs TEN Key Injuries

Rams vs Titans: Key Matchups

Titans’ Offensive Line vs Rams’ Pass Rush

This is the marquee matchup and where the game will likely be won or lost. The Rams’ defensive front, led by Jared Verse, has a massive advantage over a Titans offensive line that is without starting right tackle JC Latham. Backups Olisaemeka Udoh and/or John Ojukwu will be tasked with slowing down Verse, a battle that heavily favors the Rams.

Running Game vs Run Defense

The Rams’ ground game was surprisingly ineffective in Week 1, with Kyren Williams averaging just 2.9 yards per carry. They’ll look to get back on track against a Titans run defense that was gashed for 151 yards and 5.0 yards per carry, including a 50-yard burst. If the Rams can establish the run, it will open up their vaunted play-action passing game.

The Titans will lean on Tony Pollard to create some semblance of offensive balance, but he faces a stout Rams front that held its Week 1 opponent to just over 4.2 yards per carry.

Pass Catchers vs Secondary

Puka Nacua and new addition Davante Adams form a formidable duo for the Rams. Their route-running prowess will challenge a Titans secondary that is still gelling. Expect Stafford to exploit matchups and find open receivers in the intermediate part of the field.

On the other side, Titans’ top receiver Calvin Ridley and rookie Elic Ayomanor will have a tough time creating separation against a well-coached Rams secondary. Tennessee’s passing game will likely rely on quick, short throws to mitigate pressure, limiting big-play opportunities..

Rams vs Titans Player Props

NFL player props as of September 14 at DraftKings.

Stafford’s passing-yards prop of 235.5 is low against a Tennessee defense that is susceptible to big plays. Cameron Ward’s line is set at 200.5, but with the pressure he’s likely to face, taking the under is tempting.

Kyren Williams’ rushing line is set at 74.5 yards, which is high given his Week 1 struggles and the Rams’ OL injuries. The better value might be on his receptions prop (O 1.5 at -174), as he could be a frequent check-down option for Stafford.

Puka Nacua’s receiving line of 82.5 yards is ambitious, but he is Stafford’s top target and should see a heavy workload.

For the Titans, Tony Pollard will be the focal point of the offense, making his over on rushing yards (66.5) and receptions (2.5) intriguing plays if you believe Tennessee can keep the game competitive.

Los Angeles Rams vs Tennessee Titans Picks

• Against the Spread: Los Angeles Rams -5.5 (-105) at FanDuel
• Over/Under: Under 41.5 (-105) at FanDuel
• Player Prop: Matthew Stafford over 235.5 Passing Yards (-113) at DraftKings

This game boils down to a significant mismatch in the trenches and at the quarterback position. The Tennessee Titans are in the early stages of a rebuild, and their vulnerabilities were on full display in Week 1. Throwing a rookie quarterback to the wolves behind an injured and ineffective offensive line is a recipe for disaster, especially against a defense featuring a premier pass rusher in Jared Verse. The Titans allowed six sacks last week, and that number could easily be matched or surpassed by a Rams front that will be pinning its ears back all afternoon. The Titans’ inability to protect Cam Ward will cripple their offense, making it incredibly difficult to sustain drives and put points on the board.

On the other side, Matthew Stafford and the Los Angeles Rams offense may not be firing on all cylinders, particularly in the run game, but they are efficient and experienced. Stafford will methodically pick apart a young Titans defense that is prone to mistakes. The betting trends are overwhelmingly one-sided for a reason. The Rams are a remarkable 8-1 ATS in their last nine games and have covered in six straight on the road. Meanwhile, the Titans are an abysmal 0-8 ATS in their last eight home games and 1-9 ATS in their last 10 games following a loss. The line of -5.5 is more than manageable for a superior Rams team facing a struggling opponent. The massive drop in the total from 45.5 to 41.5 also points towards a game dominated by the Rams’ defense.

LAR vs TEN Public Betting Splits

Public and sharp bettors are aligned on this contest, with the majority of wagers (51%) and money (74%) coming in on the Los Angeles Rams to cover the spread in the Week 2 NFL public betting trends. This consensus is also driving the moneyline price up for the Rams and is a strong indicator of market confidence in the road favorite.

The total has seen heavy action on the under (91% of wagers and handle), causing the line to drop a full point from its opening number of 42.5, suggesting that oddsmakers and bettors alike anticipate a dominant defensive performance from the Rams against a rookie quarterback and a compromised offensive line.

Sign Up for the Latest Missouri Updates

Get the latest Missouri sports betting news for the launch + info on potential pre-registration and signup promos by subscribing to the SBD newsletter!