LSU vs Arkansas Picks, Predictions & Betting Lines

• The Arkansas Razorbacks are very slight favorites in their College World Series opener with the LSU Tigers
• Arkansas and LSU top the futures list in the College World Series.
• Get my LSU vs Arkansas picks, predictions, and betting lines below.

The LSU Tigers (48-15) are in Omaha, Nebraska, to open their College World Series on Saturday night against the Arkansas Razorbacks (48-13). The winner will stay in the winner’s bracket and play UCLA or Murray State on Monday.

Arkansas is a favorite in this contest, with first pitch scheduled for 7pm ET on Saturday from Charles Schwab Field in Omaha, Nebraska. Coverage will be broadcast on ESPN.

Yes, it is time to break down the Tigers vs Razorbacks rematch.

LSU vs Arkansas Odds

The Chanticleers are only +120 underdogs on the moneyline, as they take on the team seeded fourth overall heading into the NCAA Tournament. The Tigers have -154 odds on the moneyline and are -1.5 (+105) on the runline. The total stands now at 11 runs.

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Odds as of June 14 at FanDuel. See the latest news and updates on FanDuel Louisiana.  

The College World Series features eight teams in a double-elimination format with two brackets of four teams each. Both LSU and Arkansas are among the top two favorites to win the 2025 Men’s College World Series.

LSU vs Arkansas Picks & Predictions

• LSU and Arkansas Under 9.5 Runs (-122 at FanDuel)

We get a very good matchup from these two SEC teams as lefty Kade Anderson takes the mound for LSU. On the other side, Zach Root starts for Arkansas. Both pitchers are capable of going deep in ball games. Anderson struck out 163 batters this season and was 13th in strikeout-to-walk ratio at 5.82. Do not forget that 14.24 K’s per 9.

Root has been equally incredible during the 2025 season, posting a 3.59 ERA and an 8-5 record through 17 starts. The opposition batted a mere .221 against the 6-2 left-hander. Root struck out 13 batters in 13 innings, allowing only one earned run in postseason play. 

Anderson went 10-1 with a 3.58 ERA during the season. Root faced LSU earlier in the season and was in line for the win (2 ER in 6 IP). However, the LSU bats got to the Arkansas bullpen in a 5-4 triumph.

However, LSU is always more well-known for its pitching. Look at how the Tigers won another National Championship in 2023 with Paul Skenes and the Tigers’ bullpen. It is no exception this season. Casan Evans may be a Freshman, but his six saves and 1.90 ERA in 17 appearances are a real game-changer as a stopper. Arkansas is no slouch as a pitching staff (3.91 ERA, 646 K’s in 522 IP), and they are the third seed. LSU is sixth. However, the experience tells the tale.

LSU has won seven championships in all. This is Arkansas’s first MCWS appearance.

The Tigers have won nine of the past 13 series against the Razorbacks. Furthermore, LSU is well-rested, which makes them even more dangerous. Arkansas carries the top offense in the SEC, but against LSU, the Razorbacks have struggled in critical moments. The Aloy (Wehiwa and Kuhio) brothers have combined for 33 home runs and 134 RBI’s.

Again, LSU does not have to mash the ball here. Simply, the Tigers must be patient against a fiery pitching staff. If the Razorbacks do not let the nerves get to them, that will make them an even tougher foe.

It is no secret Root and Arkansas have revenge on their minds.

It will be interesting to see how Arkansas responds on the big stage. We saw Coastal Carolina find a way to extend their winning streak on Friday against Arizona.

As much as the Over is tempting, the Under in what feels like a pitcher’s duel is more likely on Saturday night.

Instead, I like LSU to help with the game total and win on the moneyline this Saturday. The Tigers are second among the eight teams at +250 to win the National Championship and -106 to win their College World Series opener. Let it ride!