Florida vs Ole Miss Picks & Predictions on ESPN (Feb 21)

• Ole Miss hosts No. 12 Florida on Saturday afternoon
• Florida looks to build on their six-game winning streak
• Alex Condon coming off back-to-back double-doubles

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The Florida Gators (20-6) and Ole Miss Rebels (11-5) square off in a battle of teams heading in two different directions. Tip-off is scheduled for 12:00 PM ET at The Sandy and John Black Pavilion at Ole Miss on ESPN.

Florida has rattled off six straight wins, while Ole Miss has dropped eight straight and is a daunting 13.5-point this afternoon. Will the Gators remain in sole possession of first place in the conference? Our deep-dive analysis breaks down the key angles for this matchup.

Florida vs Ole Miss Picks & Predictions

The defending national champions are strong favorites heading into this game, winning their last six games by an average margin of 22 points. They’re also the best rebounding team in the conference, and their size will undoubtedly exploit Ole Miss’s biggest weakness.

Spread Pick: Florida -13.5 (-102 at DraftKings)

The Rebels had a tough time keeping Texas A&M off the glass in their last game. They surrendered 13 offensive rebounds for 18 second-chance points while being outscored 50-34 in the paint. That’s a recipe for disaster against center Rueben Chinyelu and junior forward Alex Condon, who is in the midst of a late-season surge.

Player Prop Pick: Alex Condon Over 20.5 Total Points + Rebounds (-108 at FanDuel)

Condon has logged two consecutive double-double performances, recording 20 points and 10 rebounds Tuesday against South Carolina and 14 points with 11 boards last Saturday against Kentucky. If you factor in Chinyelu’s 12.0 rebounds per game, there won’t be many second-chance opportunities for Ole Miss. They will need to capitalize on every possession to stay within reach in this one.

Florida vs Ole Miss Tale of the Tape

Key Mismatch: As mentioned above, Florida will likely dominate the glass, averaging over 12 more rebounds per game than Ole Miss.

Florida vs Ole Miss Odds

• Moneyline: Florida -1100 | Ole Miss +700
• Spread: Florida -13.5 (-102) | Ole Miss +13.5 (-118)
• Total: Over 150.5 (-112) | Under 150.5 (-108)

Odds as of February 21, 2026, at 1:30 AM ET from DraftKings Sportsbook.

Moneyline Payout Calculation

For bettors assessing the risk-reward ratio on a standard $20 wager:

• Betting Florida (-1100): Returns a profit of $1.82 (Total Payout: $21.82)
• Betting Ole Miss (+700): Returns a profit of $140.00 (Total Payout: $160.00)

Florida vs Ole Miss Public-Betting Splits

The data from Saturday’s college basketball public betting percentages reveal confidence in Florida cruising over Ole Miss without much trouble.

Moneyline Splits

The market views Florida as a comfortable piece in a parlay, with the money following suit.

• Florida Gators: 94% of bets | 87% of money
• Ole Miss Rebels: 6% of bets | 13% of money

ATS Splits

The spread market highlights a similar trend as the moneyline.

• Florida Gators: 72% of bets, 74% of money
• Ole Miss Rebels: 28% of bets, 26% of money

Total Market

The public is split on on whether we will get am offensive showcase or defensive struggle.

• Over 149.5: 52% of bets, 56% of money
• Under 149.5: 48% of bets, 44% of money

Florida & Ole Miss March Madness Odds

The fallout from this game could affect Florida’s March Madness odds.

Florida

• Open: +2000
• Now: +2500

Ole Miss

Now: +70000

Open: N/A

How to Watch Florida at Ole Miss?

Viewers will be able to watch Florida at Ole Miss live on ESPN.