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A.I. College Football Picks for Week 7 – ATS & O/U Predictions from Sportradar Model

Brady Trettenero

By Brady Trettenero in College Football

Updated: October 9, 2025 at 5:04 am EDT

Published:


Oregon quarterback Dante Moore takes a snap as the Oregon Ducks face the Penn State Nittany Lions on Sept. 27, 2025, at Beaver Stadium in University Park, Pennsylvania.
  • SportRadar’s college football AI picks struggled in Week 6, posting a 4-6 ATS record but maintained their strong totals performance at 6-4 on over/under predictions
  • The AI model continues finding value on unders, hitting 60% of totals this season with defensive battles dominating the college football landscape
  • Below, see AI picks for Week 7’s biggest games, with the model backing several home underdogs in key conference matchups

SportRadar’s AI model hit a rough patch on spreads in Week 6, going just 4-6 ATS. But the college football AI picks stayed hot on totals, correctly identifying another batch of defensive struggles and hitting 6 of 10 over/under predictions.

Week 7 brings another loaded slate of conference games with playoff implications. From the Red River Rivalry getting its first SEC edition to undefeated teams clashing in Eugene, the AI college football predictions have analyzed every angle in the college football odds.

AI College Football Picks for Week 7

GameATS PickO/U Pick
Indiana vs OregonORE -7.5Under 55.5
Ohio State vs IllinoisILL +14Under 49.5
Alabama vs MissouriMIZ +3Under 51.5
Michigan vs USCUSC -2.5Over 57.5
Florida vs Texas A&MTAMU -7.5Under 46.5
USF vs North TexasUNT MLUnder 66.5
Nebraska vs MarylandMD +6.5Under 47.5
Georgia vs AuburnAUB +3.5Under 45.5
Oklahoma vs TexasTEX -1.5Under 43.5
South Carolina vs LSUSCAR +8.5Under 44

AI college football predictions record to date:

  • ATS picks: 25-25
  • O/U picks: 30-20

College football AI picks generated on October 9, 2025. Check out the top college football betting apps ahead of Week 7.

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Model Pounds Unders in Defensive Week

The AI continues its season-long trend of targeting unders, taking them in 9 of 10 games this week. After correctly identifying low-scoring affairs in Week 6 like Miami-Florida State (50 total points) and Mississippi State-Texas A&M (40 points), the model sees more defensive battles ahead.

The Red River Rivalry total at 43.5 looks especially sharp. The line plummeted 13 points from its opener, and the AI backs it to go even lower with Oklahoma allowing just 7.2 points per game meeting a Texas defense yielding 11.6.

Georgia-Auburn’s total dropping from 50.5 to 45.5 caught the model’s attention. Auburn’s elite pass rush (16 sacks) against a Georgia team that’s just 1-4 ATS creates the perfect recipe for an under. The Tigers have allowed just 16 points per game while Georgia has consistently failed to blow teams out.

Sharp Line Movement Drives AI Picks

Several massive line moves influenced the college football AI predictions this week. Alabama-Missouri saw the sharpest adjustment, with the Tide dropping from -6.5 to -3 as money poured in on the undefeated Tigers at home.

The Red River Rivalry line collapsed from Texas -11.5 (offseason) all the way down to -1.5, a 10-point swing that has the AI backing the Longhorns to bounce back. Despite Oklahoma’s elite defense, the model sees value after such dramatic overcorrection.

Michigan-USC flipped completely, going from Michigan -1.5 to USC -2.5. The four-point swing has the AI siding with the Trojans’ explosive offense at home. This is one of only two overs the model likes, expecting USC’s 48.4 points per game average to overwhelm Michigan’s defense.

Key Matchup Analysis

Indiana vs Oregon: The model backs Oregon despite the line sliding from -14 to -7.5. Autzen Stadium’s 18-game winning streak and Oregon’s elite offensive line (just one sack allowed) should be too much for Indiana’s first true road test.

Georgia vs Auburn: The AI loves Auburn getting 3.5 after the line dropped from 7.5. Georgia’s 1-4 ATS record screams fade, and Auburn’s defense is built for this exact type of game – a low-scoring slugfest at Jordan-Hare.

Illinois vs Ohio State: Illinois’ 5-1 ATS record and +7 turnover differential has the model backing them to keep it close. The Buckeyes are dominant, but asking them to cover 14 on the road against a hot team feels like too much.

AI College Football Picks – Results from Week 6

GameATS PickO/U Pick
Vanderbilt vs AlabamaVAN +10.5 LOSSOver 55.5 LOSS
Boise State vs Notre DameBSU +20.5 LOSSOver 62.5 LOSS
Ohio State vs MinnesotaOSU -23.5 WINUnder 44.5 LOSS
Texas Tech vs HoustonHOU +11.5 LOSSUnder 51.5 WIN
Texas vs FloridaTEX -6.5 LOSSUnder 41.5 LOSS
Miami vs Florida StateFSU +4.5 LOSSUnder 53.5 WIN
Virginia vs LouisvilleUVA +6.5 WINOver 61.5 LOSS
Iowa State vs CincinnatiCIN -1.5 WINOver 54.5 WIN
Indiana vs OregonIND +10 LOSSUnder 52.5 WIN
Mississippi State vs Texas A&MMSST +14.5 LOSSUnder 55.5 WIN
Washington vs MarylandWASH +5.5 WINUnder 52.5 WIN

The model’s struggles came primarily on road underdogs that couldn’t keep pace. Vanderbilt, Boise State, and Mississippi State all failed to cover despite getting double digits. The only road favorite in the picks was Texas at Florida, and they lost outright.

The bright spot was totals performance, correctly nailing unders in games like Mississippi State-Texas A&M (40 total points) and Washington-Maryland (44 points).

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Brady Trettenero
Brady Trettenero

Lead NHL & NCAAF Editor

Brady is the lead NHL and College Football editor at Sports Betting Dime, where he specializes in betting odds and data-driven analysis. Brady has over 10 years experience working in sports media, with work published by outlets such as ESPN, CBS Sports, Yahoo! Sports and Fox Sports.

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