CFB Conference Championship Picks – A.I. Predictions for All 5 Saturday Games (Dec. 6)
By Brady Trettenero in College Football
Updated: December 6, 2025 at 4:34 am ESTPublished:
- Our A.I. has generated its best picks for Saturday’s five conference championship games
- Power Four titles are on the line with massive CFP implications
- See the best championship game picks based on our A.I.’s calculations for December 6
Saturday’s college football conference championships bring five title games with massive College Football Playoff stakes. The Power Four conferences headline the slate, with Ohio State facing Indiana in a rare 1 vs. 2 showdown and Georgia battling Alabama in the SEC Championship Game.
Friday’s Group of Five championships delivered mixed results for our A.I. model. The model went 1-3 against the spread, with only Troy covering the massive number against James Madison. On totals, the A.I. finished 2-2, correctly calling the under in the Sun Belt title game and the over in the Mountain West championship.
I’ve asked our internal A.I. to generate picks for Saturday’s CFB conference championships. The table below lists all five matchups with the A.I.’s against-the-spread and over/under selections, followed by detailed reasoning for each pick.
College Football Conference Championship Picks – Saturday, December 6
A.I. picks and odds as of Dec. 5. New customers can check out the best college football betting apps and claim bonuses to bet on conference championship games.
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Miami (OH) @ Western Michigan – MAC Championship Pick
The MAC Championship kicks off Saturday’s slate at Ford Field, and the A.I. likes Miami as a short underdog. Western Michigan enters with momentum after winning eight of nine following an 0-3 start, but the model sees value on the RedHawks.
Miami beat Western Michigan 26-17 back in Week 9, outgaining them 160-61 in the fourth quarter alone. The RedHawks are making their third straight championship appearance and know how to navigate these situations.
Sharp money has backed Miami despite quarterback changes, with professionals seeing value in the experienced program. Western Michigan’s defense has been strong, led by linebacker Nadame Tucker with 18.5 tackles for loss and 12 sacks.
The A.I. believes Miami’s championship experience keeps this game close. The model also likes the under 43.5, expecting a defensive grind between two physical teams.
BYU @ Texas Tech – Big 12 Championship Pick
Texas Tech crushed BYU 29-7 back on November 8, but the A.I. sees the Cougars covering the 12.5-point spread in the rematch. BYU enters this game desperate, knowing a loss likely ends their playoff hopes despite an 11-1 record.
The Red Raiders have been dominant defensively, allowing more than 17 points just twice all season. Texas Tech’s defense overachieved projections by 14 points per game in November.
But 12.5 points is a massive spread in a championship game, and the model believes BYU keeps it closer this time. Running back LJ Martin should be healthier for BYU than in the first meeting, giving the Cougars a better ground game.
Quarterback Bear Bachmeier struggled with just 188 yards and two turnovers in the initial matchup, but the A.I. expects improved execution in a must-win scenario. The model also likes the under, reasoning that Texas Tech’s suffocating defense limits scoring opportunities for both teams.
Georgia @ Alabama – SEC Championship Pick
The fourth Georgia-Alabama SEC Championship Game in eight years kicks off at 4 p.m. in Atlanta, and the A.I. backs the Bulldogs to cover the 2.5-point spread. Alabama beat Georgia 24-21 back in October, but the model sees this as a revenge spot for the Dawgs.
Both teams score at nearly identical rates. Alabama averages 32.9 points per game compared to Georgia’s 32.1, and both convert around 46% on third down.
The deciding factor in the A.I.’s view comes down to special teams. Georgia’s field goal accuracy sits at 93.8% compared to Alabama’s concerning 65.0% mark, and in a game this tight, reliable kicking matters.
Georgia’s defense has been dominant lately, allowing just 22 total points over their last three games. The Bulldogs also outgained Alabama 6.7 yards per play to 5.2 in their first meeting but still lost.
Both teams have committed just 11 turnovers all season, suggesting a methodical, possession-based game. The A.I. likes the under 48.5, expecting championship-level defensive intensity to keep scoring down.
Duke @ Virginia – ACC Championship Pick
Virginia dominated the first meeting three weeks ago, rolling 34-17 behind 316 passing yards from Chandler Morris. The A.I. backs the Cavaliers to cover the 4-point spread in the rematch, with sharp money overwhelmingly supporting Virginia.
Professional bettors have put 86.03% of spread handle on Virginia, signaling strong confidence in the Cavaliers. The model points to a massive gap in third-down conversions.
Virginia converts at a 49.2% rate, compared to Duke’s 39.6%, giving the Cavaliers extra possessions and clock control. The weather at Bank of America Stadium supports the under as well.
Forecasted mist with 6 mph winds creates challenging conditions for passing attacks, favoring ground-based offenses. Duke quarterback Darian Mensah has been on fire lately, but the A.I. believes Virginia’s ability to control possession and superior efficiency in critical situations leads to a comfortable win.
The model likes the under 57.5, expecting the weather and methodical offense to keep scoring down.
Indiana @ Ohio State – Big Ten Championship Pick
The nation’s top two teams square off at Lucas Oil Stadium in a rare 1 vs. 2 Big Ten Championship Game. Both teams are 12-0 and locked into first-round playoff byes regardless of the outcome, but the A.I. backs Ohio State to cover the 4-point spread.
Indiana averages an explosive 44.3 points per game, but sharp money tells a different story. Professional bettors have backed Ohio State with 76.15% of spread handle, indicating confidence the Buckeyes win by more than a field goal.
The model points to Ohio State’s elite 56.9% third-down conversion rate, marginally better than Indiana’s 56.6% mark. Indiana struggled against the only two elite defenses they faced last year, averaging just 215 yards in losses to Ohio State and Notre Dame.
The Hoosiers’ offensive line faces its toughest test against the nation’s best defense. While Indiana’s +17 turnover differential shows excellent ball security, the A.I. believes Ohio State’s superior defense in a neutral-site environment makes the difference.
The model also likes the under 47.5, expecting methodical offenses that sustain long drives and consume clock.
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Lead NHL & NCAAF Editor
Brady is the lead NHL and College Football editor at Sports Betting Dime, where he specializes in betting odds and data-driven analysis. Brady has over 10 years experience working in sports media, with work published by outlets such as ESPN, CBS Sports, Yahoo! Sports and Fox Sports.