College GameDay Week 2: Location, Time, Odds & Picks

• ESPN’s College GameDay heads to Norman for No. 15 Michigan at No. 18 Oklahoma on Saturday
• The show runs from 9 AM to noon ET with NBA star Trae Young as guest picker
• Keep reading for College GameDay location details, Week 2 odds, and picks from the crew and experts

College GameDay kicks off its post-Lee Corso era in Norman, Oklahoma this Saturday. After the legendary analyst’s retirement last week, the show rolls into its 10th visit to Norman for a top-20 clash between Michigan and Oklahoma.

The Sooners host the show at South Oval on campus, with pit access opening at 6:30 AM ET for fans wanting prime spots. Former Oklahoma basketball star and current Atlanta Hawks guard Trae Young will serve as celebrity guest picker in the college football odds.

College GameDay Details

Oklahoma holds a 6-3 record when hosting GameDay at home, though their last appearance ended poorly with a 25-15 loss to Tennessee in 2024. The Sooners are 42nd all-time in GameDay appearances.

Per the college football public betting trends, this week’s featured games have seen major line movement. Sharp money has created value opportunities across the board.

GameDay Crew Picks

Michigan vs Oklahoma Odds & Analysis

Kickoff: 7:30 PM ET on ABC at Gaylord Family Oklahoma Memorial Stadium

The line opened at Oklahoma -1.5 but quickly shot to -5.5 before settling back at five. This movement tells a story about where the smart money landed early.

Michigan quarterback Bryce Underwood threw for 251 yards in his debut, averaging 8.1 yards per attempt against New Mexico. But Norman’s hostile environment presents a different challenge entirely. Oklahoma’s John Mateer connected with offensive coordinator Ben Arbuckle from Washington State, throwing for nearly 400 yards against Illinois State.

Michigan is 3-0 ATS as underdogs under Sherrone Moore, including upsets over Alabama and Ohio State. But Oklahoma’s home field advantage and offensive chemistry give them the edge. The Sooners are just 2-4 ATS in their last six as favorites, but this feels different with playoff implications already emerging.

• Our Pick: Oklahoma -5 (-110)

Other Week 2 Featured Games

Iowa vs Iowa State

Line: Iowa State -3.5 | Total: 41.5 | Kickoff: 12:00 PM ET on FOX

The Cy-Hawk rivalry features a fascinating trend: the road team has won six straight meetings. Iowa’s defense held Albany to 134 total yards while freshman Xavier Williams exploded for 122 rushing yards. The Hawkeyes rushed for 310 total yards behind a revamped offensive line.

Iowa State quarterback Rocco Becht has thrown seven career pick-sixes, most among active FBS players. That’s dangerous against an Iowa defense with 17 straight seasons recording a pick-six. The Cyclones lost both 1,000-yard receivers from last season.

• Pick: Iowa +3.5 (-110)

Oregon vs Oklahoma State

Line: Oregon -27.5 | Total: 55.5 | Kickoff: 3:30 PM ET on CBS

The Cowboys flipped 65 scholarship players and face a massive talent gap. Oregon demolished Montana State 59-13 while rotating liberally. Quarterback Dante Moore looked sharp with three touchdown passes.

• Pick: Oregon -27.5 (-110)

Duke vs Illinois

Line: Illinois -3 | Total: 49.5 | Kickoff: 12:00 PM ET on ESPN

Duke quarterback Darian Mensah threw for 389 yards in his debut against Elon. The Blue Devils are 9-1 in their last 10 home games and 6-0 ATS against Big Ten opponents. Illinois lost key weapons from last year’s 10-win team.

• Pick: Duke +3 (-110)

Line Shopping Guide

Check back Saturday morning for updates on the GameDay crew’s picks. The professionals are targeting home favorites and road underdogs across Week 2’s loaded slate.