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College GameDay Week 4: Location, Time, Odds & Picks

Brady Trettenero

By Brady Trettenero in College Football

Published:


Pat McAfee takes the stage at ESPN College GameDay
Pat McAfee takes the stage at ESPN College GameDay ahead of the University of Oklahoma-Michigan College football game on Sep 6, 2025 in Norman.
  • ESPN’s College GameDay heads to Miami for unranked Florida at No. 4 Miami on Saturday
  • The show runs from 9 AM to noon ET with NHL star Matthew Tkachuk as guest picker
  • Keep reading for College GameDay location details, Week 4 odds, and picks from the crew and experts

College GameDay’s making a controversial stop in Miami for Week 4. The decision to pick an unranked Florida team visiting No. 4 Miami over ranked matchups like Illinois at Indiana has many CFB fans questioning ESPN’s logic.

The Hurricanes host the show at Lakeside Patio on campus. Florida Panthers star Matthew Tkachuk becomes the first NHL player to serve as celebrity guest picker in the college football odds.

College GameDay Details

DetailInformation
LocationLakeside Patio, University of Miami
Time9:00 AM – 12:00 PM ET
ChannelESPN/ESPNU
Guest PickerMatthew Tkachuk

GameDay heads to Miami’s campus for the first time since 2017, when the Canes crushed Notre Dame 41-8. The Canes are 7-1 all-time in GameDay appearances.

The Hurricanes are 3-0 this season and looking to stay unbeaten against a Florida team that’s been a disaster after losing to USF and LSU.

College GameDay Picks – Week 4

GameHowardSabanMcAfeeHerbstreitTkachuk
WISC @ MD
MICH @ NEB
TTU @ UTAH
ILL @ IND
AUB @ OU
FLA @ MIA

Week 3 GameDay Results

PickerWeek 3Best PickWorst Pick
Desmond Howard3-6GeorgiaWisconsin*
Nick Saban4-5Ole MissNotre Dame
Pat McAfee6-3West VirginiaTennessee
Kirk Herbstreit3-5VanderbiltNotre Dame
Candace Parker3-6Alabama*Notre Dame

*Indicates spread pick

Pat McAfee was the only Gameday Crew picker to post a positive record last weekend. McAfee nailed huge upsets, including GA Tech vs Clemson. He was also the only one on the set to predict the Texas A&M upset vs Notre Dame and the WVU upset win over Pitt.

Florida vs Miami Odds & Analysis

Kickoff: 7:30 PM ET on ABC at Hard Rock Stadium

Bet TypeFloridaMiami
Spread+7.5 (-110)-7.5 (-110)
Moneyline+245-305
TotalO 50.5 (-118)U 50.5 (-102)

The total has plummeted from 55.5 to 50.5 after DJ Lagway’s five-interception disaster last week. Miami’s Carson Beck has been surgical with a 7-2 TD-INT ratio.

Florida’s offense has been a complete liability. Lagway has six interceptions through three games while the Gators manage just 12 points per contest. Miami’s averaging over 300 passing yards behind Beck’s elite play. With Florida’s pass rush generating just two sacks all season, Beck should pick them apart.

  • Our Pick: Miami -7.5 (-110)

Auburn at Oklahoma

Line: Oklahoma -6.5 | Total: 48.5 | Kickoff: 3:30 PM ET on ABC

This SEC opener features former Oklahoma QB Jackson Arnold returning to Norman with Auburn. The line moved from Oklahoma -4.5 to -6.5 as money poured in on the home team.

Oklahoma’s defense has been dominant, holding opponents to 0-for-4 touchdowns in the red zone. But their -5 turnover differential is a massive red flag. Auburn’s rushing attack averages 5.8 yards per carry and could exploit that sloppiness. Arnold’s revenge factor makes Auburn attractive catching points.

  • Pick: Auburn +6.5 (-108)

Texas Tech at Utah

Line: Utah -3.5 | Total: 57.5 | Kickoff: 12:00 PM ET on FOX

This Big 12 battle kicks off FOX’s Big Noon Saturday. Both teams are 3-0 with Texas Tech averaging 58 points per game while Utah’s posted a 94-15 scoring edge.

The line has bounced around, opening at -3.5 before hitting -3 and now back to -3.5. Behren Morton has been nearly flawless while Utah’s Devon Dampier brings dual-threat ability. The altitude at Rice-Eccles Stadium and Utah’s dominant 290 rushing yards per game give them the edge to control this game.

  • Pick: Utah -3.5 (-110)

Illinois at Indiana

Line: Indiana -5.5 | Total: 47.5 | Kickoff: 7:30 PM ET on NBC

The first ranked matchup between these teams since 1950 deserved GameDay consideration. Indiana’s averaging 52 points per game with 300-plus rushing yards.

Illinois counters with Luke Altmyer’s 72% completion rate and a defense allowing just one touchdown per game. Computer models slightly favor Indiana but this projects as a coin flip. The Illini have played the tougher schedule and can keep this close.

  • Pick: Illinois +5.5 (-110)

Michigan at Nebraska

Line: Michigan -2.5 | Total: 45.5 | Kickoff: 3:30 PM ET on CBS

The Wolverines travel to Lincoln without suspended coach Sherrone Moore. Dylan Raiola faces his first major test leading the undefeated Cornhuskers.

Nebraska’s Raiola has a pristine 9-0 TD-INT ratio through three games. Michigan counters with Justice Haynes, who’s rushed for 100-plus yards in all three games. The hostile Memorial Stadium environment and Nebraska’s revenge motive after last year’s 45-7 loss give them the edge.

  • Pick: Nebraska +2.5 (-108)

Maryland at Wisconsin

Line: Wisconsin -10 | Total: 44.5 | Kickoff: 12:00 PM ET on NBC

The line ballooned from Wisconsin -7.5 to -10 despite Maryland’s 3-0 start. The Terrapins lead the nation with seven interceptions and have generated 10 sacks.

Wisconsin’s offensive line struggled mightily against Alabama with communication breakdowns. Malik Washington has been efficient for Maryland with a 6-1 TD-INT ratio. The Badgers are just 1-4 ATS in their last five games. Maryland’s defense can keep this within the number.

  • Pick: Maryland +10 (-108)

Line Shopping Guide

GameBest SpreadSportsbook
Florida-MiamiMIA Caesars
Auburn-OklahomaAUB +7FanDuel
Texas Tech-UtahTTU +3.5BetMGM
Michigan-NebraskaNEB +3DraftKings

Check back Saturday morning for updates on the GameDay crew’s picks. After mixed results in Week 3, the professionals are targeting home underdogs and unders across Week 4’s loaded slate.

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Brady Trettenero
Brady Trettenero

Lead NHL & NCAAF Editor

Brady is the lead NHL and College Football editor at Sports Betting Dime, where he specializes in betting odds and data-driven analysis. Brady has over 10 years experience working in sports media, with work published by outlets such as ESPN, CBS Sports, Yahoo! Sports and Fox Sports.

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