Ohio State vs Washington Preview: Prediction, Line, Betting Trends & H2H History

• I’ve made my early Ohio State vs Washington prediction for Saturday’s Big Ten showdown
• The Buckeyes enter as road favorites despite Washington’s 22-game home winning streak
• Check out my Ohio State vs Washington preview with prediction, betting odds, trends and more

The defending national champion Ohio State Buckeyes bring their top-ranked defense to Seattle for a massive Big Ten opener against the Washington Huskies. Both teams are 3-0, but Ohio State (3-0) sits atop the AP Poll while Washington (3-0) remains unranked despite their perfect start.

The Huskies host at Husky Stadium at 12:30 PM PT on Saturday, September 27th, with CBS broadcasting nationally. The OSU vs. UW odds show massive line movement, which can tell us a lot about how this matchup could play out.

I’ve analyzed my Ohio State vs Washington prediction for Saturday’s clash along with the latest line movement and betting trends.

Ohio State vs Washington Prediction & Pick

• Washington +8 (-110 at Caesars)

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Ohio State’s defense has been historically dominant. The Buckeyes are allowing just 5.3 points per game and haven’t allowed a red zone score all season. They’re the only FBS team holding all three opponents under 10 points this year. Their 16 total points allowed are the fewest through three games since 1975.

But they haven’t faced an offense like Washington’s. The Huskies are averaging 55.7 points per game and haven’t punted in their last 25 drives. They’re converting third downs at a 75% clip and scoring on 79.3% of their possessions. Both marks lead the nation.

The line tells you everything. This opened at Ohio State -14 and has been bet down to -8. That’s massive movement for a game involving the #1 team. Big-money bettors clearly see value in Washington getting points at home.

Julian Sayin has been surgical for Ohio State. He’s completing 78.9% of his passes and is a perfect 9-for-9 with six touchdowns on throws of 20+ yards. But this is his first true road start. He got rattled against Ohio University and now faces the loudest environment in college football.

Washington quarterback Demond Williams Jr. brings a different dimension. He’s one of two FBS players averaging 250+ passing yards and 50+ rushing yards per game. His mobility will test Ohio State’s discipline. The Buckeyes haven’t allowed a quarterback 40+ rushing yards this season, but Williams has 13 explosive runs already.

The X-factor is Jonah Coleman. He leads the nation with 10 total touchdowns through just three games. Last week against Washington State, he had 104 receiving yards to go with his rushing production. Ohio State’s run defense is elite, but Coleman presents matchup problems as both a runner and receiver.

Husky Stadium is a fortress. Washington has won 22 straight home games, the longest active streak in college football. They’ve beaten four ranked teams during this run. The crowd noise will be deafening for a noon kickoff against the #1 team.

Ryan Day is 49-1 against unranked opponents with 48 of those wins by multiple scores. He’s 23-3 in Big Ten road games, but those losses came in hostile environments at Michigan (twice) and Oregon. Husky Stadium presents a similar challenge with its deafening crowd noise that could rattle the young Buckeyes.

Public money is hammering Ohio State. They’re getting 97% of moneyline bets and 68% of spread money despite the line moving against them. That reverse line movement tells me there is massive sharp action on Washington.

Considering the way the line is moving and the Huskies’ notable home-field advantage, I’m taking the points with UW at home.

Ohio State vs Washington Betting Line

The line opened with Ohio State as 14-point road favorites. It’s now down to 8 points across the board. The total sits at 52.5 after minimal movement from the opener.

The moneyline has Ohio State at -333 with Washington getting +260. Despite the public backing Ohio State heavily, the line movement toward Washington indicates professional money likes the home dog.

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Odds as of September 25, 2025, at Caesars Sportsbook. Place an early weekend wager by registering with the Caesars Sportsbook promo code.

OSU vs UW Betting Trends

Ohio State Trends:

• 6-0-1 ATS in their last 7 games
• 12-2 SU in their last 14 road games
• 8-2-1 ATS in their last 11 Week 5 games
• The total has gone UNDER in 7 of their last 10 Saturday games

Washington Trends:

• 20-0 SU in their last 20 home games
• 1-6 ATS in their last 7 games as an underdog
• The total has gone OVER in 6 of their last 6 games
• 15-3 SU in their last 18 September games

Buckeyes vs Huskies Public Betting Splits

The public is all over Ohio State despite the line movement. The Buckeyes are getting 97% of moneyline bets and 99% of the money. On the spread, tickets are split 50/50, but Ohio State is getting 68% of the money.

The total shows interesting action. More bets are on the under (54%), but more money is on the over (63%). This suggests larger wagers are backing the over despite both defenses’ strong starts.

Ohio State vs Washington H2H History

Ohio State leads the all-time series 9-3 and has won four straight meetings dating back to 1995. The Buckeyes are 4-2 all-time in Seattle. The most recent meeting was the 2019 Rose Bowl where Ohio State won 28-23 in Urban Meyer’s final game.

Washington’s last win came in 1994 when they beat the Buckeyes 25-16 in Seattle. The Huskies’ most dominant performance was a 40-7 victory at home in 1986.