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MLB All-Star Game Picks, Predictions & Odds

Brady Trettenero

By Brady Trettenero in MLB Baseball

Published:


Jul 2, 2025; Pittsburgh, Pennsylvania, USA; Pittsburgh Pirates pitcher Paul Skenes (30) walks in from the bullpen before the game against the St. Louis Cardinals at PNC Park. Mandatory Credit: Charles LeClaire-Imagn Images
  • The American League and National League clash Tuesday night at Truist Park in Atlanta for the 2025 MLB All-Star Game
  • The NL All-Stars are slight favorites despite the AL’s decade of dominance
  • See the MLB All-Star Game prediction, odds, and starting pitchers for Tuesday’s Midsummer Classic

Baseball’s brightest stars hit Atlanta on Tuesday, July 15th, for the 2025 MLB All-Star Game. The American League (10-1 in last 11 ASG) looks to continue its dominance over the National League (1-10 in last 11 ASG) at Truist Park.

First pitch is set for 8:00 pm ET, and Vegas can’t separate these teams in the MLB All-Star Game odds. Both sides carry favorable odds, although the NL All-Stars have created separation as the oddsmakers’ pick.

Let’s dive into our MLB All-Star prediction for Tuesday’s main event.

MLB All-Star Game Picks & Predictions

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Forget the fireworks. This game’s about the arms.

The numbers tell the story. Six of the last 10 All-Star Games have stayed under the total. When baseball’s elite pitchers only need to empty the tank for an inning or two, they’re virtually unhittable. They’re throwing like closers from the jump.

Tarik Skubal and Paul Skenes set the tone Tuesday night. These aren’t your average aces. Skubal’s 2.23 ERA ranks among baseball’s best, while Skenes’ 2.01 mark is even better. Both guys will be amped up, throwing harder than usual with the spotlight on.

MLB All-Star Game Starting Pitchers

Skubal (AL)StatSkenes (NL)
10-3W-L4-8
2.23ERA2.01
153K131
0.83WHIP0.96
10.9K/911.7

MLB All-Star Games bullpens are absolutely stacked. Every pitcher out there is pitching for a reason. The AL brings Garrett Crochet, Jacob deGrom, and Aroldis Chapman. The NL counters with Edwin Diaz, Robert Suarez, and Jason Adam.

It’s a stacked deck of dominant arms.

Yes, Aaron Judge is batting .355. Sure, Shohei Ohtani has mashed 32 homers. But when pitchers can max out for one inning, it’s a different story. They’re not pacing themselves for six innings. They’re bringing triple-digit heat from pitch one.

Look at the recent history. Last year’s 5-3 score was actually on the higher side. Four of the last five games stayed at seven runs or fewer. Just once did we see a real slugfest.

Here’s more: MLB teams are averaging just 4.38 runs per game this year, which is the lowest since 2015. That pitching-heavy trend gets amplified in an All-Star setting, where arms are fresh and innings are short.

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Truist Park won’t bail out the hitters either. Despite its reputation, Statcast rates it exactly league average for offense. No cheap homers here. These pitchers know the park, and they’ll exploit it.

The AL’s pitching depth gives them the edge if you’re picking sides. Their staff runs deeper, especially with Chapman closing. He’s been here before. He knows how to finish. That experience matters in a one-run game, and four of the last 10 All-Star Games have been decided by exactly one run.

At even money, the under offers the best value. Vegas knows what they’re doing setting this at 7. It’s landed there multiple times recently. But given the elite pitching on both sides, grab the plus money and root for zeroes.

MLB All-Star Game Odds July 15

Bet TypeAmerican LeagueNational League
Moneyline-105-115
Runline-1.5 (+165)+1.5 (-200)
TotalO 7.0 (-120)U 7.0 (+100)

The National League is a slight -115 favorite at BetMGM, with some sportsbooks shifting them closer to -120. Their implied win probability is 54.5%.

American League, meanwhile, is priced at -105, which is 51.2% implied probability. Oddsmakers are essentially calling this a coin flip, which makes sense given the talent on both rosters.

The total opened at 7.0 everywhere. The juice has shifted to the over at -120, which means some bettors expect runs. Don’t fall for it. The under’s still the smart play.

All-Star Game MVP Odds

PlayerTeamOdds
Shohei OhtaniNL+550
Aaron JudgeAL+700
Ronald Acuna Jr.NL+1100
Cal RaleighAL+1200
Pete Crow-ArmstrongNL+1200
Bobby Witt Jr.AL+1800
Fernando Tatis Jr.NL+1800
Freddie FreemanNL+2200
Manny MachadoNL+2200

Ohtani leads the MVP betting as the favorite at +550. Makes sense. The guy’s got 32 homers and leads off for the NL. Judge follows at +700 after his scorching .355 average through the first half.

My sleeper is Ronald Acuña Jr. at +1100. He’s playing at home in Atlanta, where he owns a 1.025 OPS this season. The crowd will be electric every time he steps up. That home-field energy could be the difference.

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Odds as of July 15 at BetMGM Sportsbook. Check out SBD’s list of the best MLB betting apps.

Brady Trettenero
Brady Trettenero

Lead NHL & NCAAF Editor

Brady is the lead NHL and College Football editor at Sports Betting Dime, where he specializes in betting odds and data-driven analysis. Brady has over 10 years experience working in sports media, with work published by outlets such as ESPN, CBS Sports, Yahoo! Sports and Fox Sports.

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