Upcoming Match-ups

Astros vs Athletics Odds, Lines, and Pick

Jordan Horrobin

by Jordan Horrobin in MLB Baseball

Updated Mar 31, 2021 · 12:15 PM PDT

Matt Chapman rounds the bases
Oakland Athletics' Matt Chapman, left, runs the bases on a home run as Houston Astros starting pitcher Zack Greinke (21) heads back to the mound during the fourth inning of the second baseball game of a doubleheader Saturday, Aug. 29, 2020, in Houston. (AP Photo/Michael Wyke)
  • The Astros and Athletics embark on a brand new season with an opening day matchup on Thursday, April 1 at 10:07 pm ET
  • Oakland’s Chris Bassitt, 32, will make his first opening day start after a breakout campaign in the shortened 2020 season
  • For the odds, matchup analysis, and best bets, check out the article below

Last season, a changing of the guard in the AL West might have revealed itself as the Astros were dethroned from the top of the division for the first time in four years. The new champion, the Athletics, appear to be building something real out there in northern California.

With a new season beginning on Thursday, April 1st, the two consensus titans of the AL West meet (first pitch at 10:07 pm ET) for the first of many matchups, in a year that could be telling about the direction of both franchises.

As it stands, the Athletics vs Astros odds are a dead heat.

Astros vs Athletics Odds

Team Moneyline Runline Over/Under Run Total at DraftKings
Houston Astros -108 -1.5 (+150) Over 8.5 (-105)
Oakland Athletics -108 +1.5 (-182) Under 8.5 (-115)

Odds as of March 31st

Greinke Gets Back to It

Unlike Bassitt, Zack Greinke is a veteran of the opening day start. Thursday will mark his fifth, albeit his first with the Astros (Royals in 2010, Diamondbacks in 2016-17, 2019).

We know Greinke as a crafty veteran who will eventually have a bust in Cooperstown. But you should also know he’s been a bust — you know, the bad kind — in opening days’ past. The six-time All-Star is 0-1 with an 8.20 ERA in his four previous opening days outings.

Oddly enough, his early-season returns in his career have been really good. Greinke’s March/April career splits include a 34-14 record, a 2.93 ERA and a 1.141 WHIP in over 400 innings. Maybe Greinke just can’t put it together on the opening day stage, or maybe the wider sample of his early-season statistics is worth paying attention to.

A’s Career Stats vs Zack Greinke

Elvis Andrus 8 0 3 .500
Mark Canha 12 0 0 .000
Matt Chapman 14 1 2 .357
Ramon Laureano 9 1 2 .556
Tony Kemp 6 0 0 .167
Mitch Moreland 0 0 0 .000
Sean Murphy 4 0 0 .250
Matt Olson 14 0 0 .143
Stephen Piscotty 12 0 1 .250
Chad Pinder 9 0 0 .333

A Chance for Andrus

In the same offseason the A’s lost free agent shortstop Marcus Semien — who finished third in MVP voting in 2019 — they gained a shortstop in Elvis Andrus via trade. Now Andrus, a 32-year-old with a staggering 12 years of service time, has an opportunity right away to make a good first impression with his new club.

Andrus’s numbers against Greinke are a bit limited, but he’s 4-for-8 with three RBIs in his career against the lefty. Having played his entire career in the AL West with the Texas Rangers, Andrus’s experience with Greinke is recent.

Andrus is coming off an abysmal 2020 season (.582 OPS in 29 games), though to be fair offense has never been his greatest strength (career 86 OPS+). Perhaps against Greinke he can make a splash in this game.

Astros Career Stats vs Chris Bassitt

Jose Altuve 14 1 2 .286
Michael Brantley 16 0 0 .250
Yordan Alvarez 5 1 2 .200
Alex Bregman 14 0 2 .286
Carlos Correa 8 0 0 .375
Jason Castro 9 0 0 .333
Aledmys Diaz 3 0 0 .333
Yuli Gurriel 19 0 3 .368
Martin Maldonado 5 0 0 .200
Kyle Tucker 10 1 4 .200

Recent Matchups

As divisional foes, the Astros and A’s are used to facing each other frequently. They just haven’t seen each other yet this year, of course, because the year is just getting started.

In the final month of the 2020 season (including the postseason), these teams met up 10 times. Oakland won six of those 10 — and nine of the past 13, if you go back further — although Houston won their divisional series matchup.

YouTube video

Oh, and guess who was the starting pitcher in the Astros’ clinching game of that series? Greinke.

That makes this an even tougher call, but we’ll still roll with the A’s on the money line after seeing Greinke falter on the opening day stage enough times already.

Pick: Oakland Athletics (-108)

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