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MLB Picks & Best Bets (Sep. 21): Wheeler, Phillies Look To Stay Perfect vs. Nationals

Philadelphia Phillies
Zack Wheeler and the Philadelphia Phillies look to build on their 6-0 season record against the Washington Nationals in Monday's matchup. Photo via @JeffSkversky (Twitter).
  • Phillies Zack Wheeler looks to build off prior success against the Washington Nationals on Monday, Sept. 21
  • Ageless wonder Adam Wainwright and the Cardinals are hot entering the I-70 series against the Royals
  • Check out the early odds and picks for MLB’s Monday slate (Sep. 21st)

A perfect record for a pitcher, and for one divisional foe against another, is at stake on Monday, September 21st as the Philadelphia Phillies head to Washington to face the Nationals. That’ll be one of the key matchups to watch among the early odds for Monday’s MLB slate.

NB: The table below displays all Sep. 21st games open for betting as of 10:00 pm ET, Sep. 20th. It may not contain all games scheduled for Sep. 21st.

MLB Odds: Sep. 21st

Team (Starter) Moneyline Runline Over/Under Run Total Game Time (Eastern)
Los Angeles Angels (D. Bundy) -191 -1.5 (-105) Over 8.5 (-120) 4:10 pm
Texas Rangers (K. Gibson) +175 +1.5 (-115) Under 8.5 (+100)
Team (Starter) Moneyline Runline Over/Under Run Total Game Time (Eastern)
Philadelphia Phillies (Z. Wheeler) -145 -1.5 (+110) Over 9.5 (-115) 6:05 pm
Washington Nationals (A. Sanchez) +134 +1.5 (-130) Under 9.5 (-105)
Team Moneyline Runline Over/Under Run Total Game Time (Eastern)
Cleveland Indians (A. Civale) -102 +1.5 (-165) Over 8.5 (+100) 6:10 pm
Chicago White Sox (D. Dunning) -108 -1.5 (+145) Under 8.5 (-120)
Team Moneyline Runline Over/Under Run Total Game Time (Eastern)
Cincinnati Reds (L. Castillo) -124 TBD Over 7.5 (-110) 6:40 pm
Milwaukee Brewers (B. Woodruff) +114 TBD Under 7.5 (-110)
Team Moneyline Runline Over/Under Run Total Game Time (Eastern)
Miami Marlins (T. Rogers) +153 +1.5 (-130) Over 9.0 (-130) 7:10 pm
Atlanta Braves (H. Ynoa) -166 -1.5 (+110) Under 9.0 (+110)
Team Moneyline Runline Over/Under Run Total Game Time (Eastern)
Kansas City Royals (C. Hernandez) +133 +1.5 (-120) Over 9.0 (-120) 8:05 pm
St. Louis Cardinals (A. Wainwright) -144 -1.5 (+100) Under 9.0 (+100)
Team Moneyline Runline Over/Under Run Total Game Time (Eastern)
Houston Astros (L. McCullers Jr.) -145 TBD Over 8.0 (-115) 9:10 pm
Seattle Mariners (M. Gonzales) +134 TBD Under 8.0 (-105)

Odds as of Sept. 20th at DraftKings.

Pick 1: Phillies Moneyline (-145) vs Nationals

Reasoning: Phillies dominating season series.

The Philadelphia Phillies were just 13-25 against the Washington Nationals in 2018-19 — but the script has flipped in 2020.

Philadelphia is 6-0 against Washington this season, including two shutouts that occurred earlier this month.

On Monday, Zack Wheeler toes the rubber for the Phillies, boasting a solid 4-0 record and 2.62 ERA in nine starts. His lone start against the Nationals was a gem, as he allowed three hits and no runs over 6.2 innings in a winning effort on Sept. 2.

Opposite Wheeler is Nationals starter Anibal Sanchez, whose lone start against the Phillies in 2020 — nine hits and four runs allowed in 3.1 innings — resulted in a loss.

Pick 2: Cardinals Moneyline (-144) vs Royals

Reasoning: Cardinals are heating up at the right time.

The only player in baseball this season with multiple complete games is also among the oldest: Adam Wainwright, who is 5-1 with a 2.87 ERA in a renaissance season for the 39-year-old.

Wainwright and the Cardinals are rolling, with four consecutive wins after completing the sweep of the Pirates on Sunday. St. Louis hasn’t been at its best offensively of late (3.2 runs scored per game in its past 10), but perhaps facing the Royals’ Cesar Hernandez will help.

Hernandez, 23, allowed three runs in three innings in his debut MLB start on Sept. 12. Now he’ll face a Cardinals team looking for a pitcher to pick on.

While the Cardinals have won four-straight, the Royals have dropped four of five. St. Louis has won two of three in this head-to-head matchup this season, and is 9-4 against Kansas City since 2018.

A two-team parlay on the Phillies and Cardinals at -145 and -144, respectively, would pay out at +186.

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