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Boston Red Sox vs Baltimore Orioles Picks, Player Props, Odds & Betting Trends (Aug. 26)

Sascha Paruk

By Sascha Paruk in MLB Baseball

Published:


Boston Red Sox shortstop Trevor Story turning a double play against the Baltimore Orioles
Aug 25, 2025; Baltimore, Maryland, USA; Boston Red Sox shortstop Trevor Story (10) throws to first as Baltimore Orioles is out at second for a double play during the sixth inning at Oriole Park at Camden Yards. Mandatory Credit: Daniel Kucin Jr.-Imagn Images
  • The red-hot Boston Red Sox face a Baltimore Orioles team struggling with injuries on Tuesday, Aug 26
  • The pitching matchup features Boston’s Lucas Giolito against Baltimore’s Kyle Bradish
  • See the Red Sox vs Orioles picks, player props, betting trends, and best odds

The Boston Red Sox (72-60, 31-35 away, 64-63-4 O/U) and Baltimore Orioles (60-71, 31-34 home, 54-69-7 O/U) continue their series at Camden Yards in Baltimore, MD, on Tuesday night. First pitch is scheduled for 6:35 pm ET with Lucas Giolito (8-2, 3.72 ERA) starting for the visitors and Kyle Bradish (2-0, 2.75 ERA) returning from the 60-day IL for the home team.

The Red Sox arrive in Baltimore with considerable momentum, having won four of their last five games, including the series opener against the O’s (4-3) last night and three of four in a massive series with the Yankees over the weekend. Boston’s offense has been firing on all cylinders, in stark contrast to an Orioles squad that has dropped four of its last five and is dealing with a lengthy injury list which includes All-Star catcher Adley Rutschman.

Below, I will set out the player props, best available odds, pitcher-vs-batter history, and our AI’s best picks for Tuesday’s game.

Go to: Player Props | Picks | Best Odds | Pitcher-vs-Batter History | Betting Splits

BOS Red Sox vs BAL Orioles Player Props

PLAYERHITSTOTAL BASESHRRBIRUNS
G. Henderson (BAL)1.5 (+178 | -242)1.5 (-112 | -120)+3600.5 (+130 | -175)0.5 (-107 | -127)
R. Mountcastle (BAL)0.5 (-269 | +195)1.5 (+117 | -152)+6000.5 (+148 | -205)0.5 (+127 | -172)
A. Bregman (BOS)0.5 (-246 | +180)1.5 (+120 | -161)+4700.5 (+178 | -246)0.5 (-105 | -130)
J. Duran (BOS)0.5 (-249 | +183)1.5 (+102 | -137)+4200.5 (+140 | -192)0.5 (-105 | -130)
T. Story (BOS)0.5 (-224 | +165)1.5 (+130 | -175)+4700.5 (+150 | -207)0.5 (+120 | -159)
PITCHERSTRIKEOUTSEARNED RUNSWALKSHITSOUTS
L. Giolito (BOS)5.5 (+110 | -145)2.5 (-125 | -109)N/A5.5 (+110 | -150)17.5 (+100 | -132)
K. Bradish (BAL)4.5 (-130 | +100)1.5 (-175 | +125)N/A4.5 (-135 | -105)15.5 (+140 | -190)

MLB player props as of Aug. 26 at DraftKings. Claim the best sportsbook promos for Tuesday’s MLB slate.

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Lucas Giolito’s strikeout prop was set at a modest 4.5 earlier in the day but has climbed to 5.5 with -145 juice now on the under. The Orioles offense has the seventh-highest strikeout rate in the league, making the over an intriguing play at +110. Giolito has been effective at limiting damage this season, and his earned-runs line of 2.5 seems fair against an Orioles lineup missing key pieces like Adley Rutschman.

For the batters, Jarren Duran’s total bases prop at 1.5 (+102) offers good value, considering his recent power surge and success at Camden Yards.

Red Sox vs Orioles Picks & Prediction

  • Over 8.5 runs (-110) at bet365
  • Boston Red Sox -1.5 runline (+146) at FanDuel
  • Giolito over 5.5 Ks (+110) at DraftKings

The foundation of this prediction rests on two core factors: the stability of Boston’s starting pitching versus the complete uncertainty for Baltimore, and the starkly contrasting momentum of the two teams’ offenses. The Red Sox are not just winning games; they are doing so convincingly on the road. The Red Sox are 8-2 on the road in their last 10 games as a favorite, and an even more impressive 6-1 on the road in their last seven against opponents with a losing record. Giolito provides a reliable arm on the mound, and he faces an Orioles lineup with which he has almost no history, giving him a significant edge.

Conversely, the Orioles are in a tailspin. They have lost four of their last five and are grappling with a decimated roster. The fact that their starter, Kyle Bradish, hasn’t pitched since mid-June adds another level of uncertainty.The O’s could wind up leaning heavily on a bullpen that sits 25th in the majors in ERA (4.76) and 24th in FIP (4.33).

The betting trends also paint a bleak picture for Baltimore at home, where they are just 1-6 (.143) as a favorite in their last seven. While they are slight underdogs tonight, that trend highlights their struggles at Camden Yards.

Given Boston’s offensive firepower and Baltimore’s pitching crisis, the Red Sox runline at significant plus-money is the most logical play.

Boston’s offense has been fueling high-scoring games, with the over hitting in 10 of the last 13 road games. Despite the line moving down to 8.5, the combination of a potent offense and a patchwork pitching staff for the Orioles points toward the over.

Baltimore Orioles vs Boston Red Sox Odds

Bet TypeRed SoxOrioles
Moneyline-110 at bet365-105 at BetMGM
Runline-1.5 (+146) at FanDuel+1.5 (-170) at Caesars
Total RunsO 8.5 (-110) at bet365U 8.5 (-103) at DraftKings

The Red Sox/Orioles moneyline is nearly a toss-up, with Boston listed as slight favorites at most books. The best ML price on Boston is -110 at bet365, while the longest odds on a Baltimore victory are -105 at BetMGM. The total is 8.5 across the board with only minor variations in price; over bettors can get -110 at bet365, while under bettors can get -103 at DraftKings. Both of those numbers were market-bests at the time of publication.

Odds as of 10:14 am ET, August 26. Check out SBD’s comprehensive list of betting sites with Apple Pay.

BOS vs BAL Odds Movement (Aug. 26)

The betting market has shown notable movement on the total, while the side betting has remained relatively stable. The total opened at 9.0 runs with juice on the under (-122), prompting oddsmakers to drop the line to 8.5. Since the adjustment, money has come in on the over, pushing the price to -115. This reverse line movement on the total suggests that, while the initial reaction was to bet the under, the current number of 8.5 is attracting buy-in for a higher-scoring game, possibly influenced by warm, humid weather conditions in Baltimore and the potent Boston offense.

The moneyline has seen a slight shift toward the Red Sox, moving from -110 to -113. This minor adjustment aligns with Tuesday’s MLB public betting patterns, which heavily favor Boston. The primary driver for market sentiment is the clear disparity in recent form and the Orioles’ extensive injury report, which included starting pitcher Kyle Bradish on the 60-day IL until today. The uncertainty surrounding who will actually take the mound for Baltimore has likely tempered heavy investment, keeping the lines tight, but the underlying factors all point in Boston’s favor.

Starting Pitcher-vs-Batter History: Giolito vs Bradish

Neither pitcher has an extensive history against tonight’s opposing lineup. The Red Sox have 39 total at-bats against Bradish, while the Orioles have just 20 against Giolito. Both pitchers have gotten the better of the H2H history, but that edge is far more pronounced on Giolito’s side.

Boston Red Sox Career Statistics vs Kyle Bradish

BATTERABH2B3BHRRBIBBKAVGOBPSLGOPS
A. Bregman61000020.167.375.167.542
J. Duran52101402.400.4001.2001.600
N. Lowe92000004.222.222.222.444
T. Story100000005.000.000.000.000
C. Wong42001211.500.6001.2501.850
M. Yoshida51000001.200.200.200.400
Totals3981026313.205.262.385.647

Bradish has completely dominated Trevor Story (0-for-10), but Jarren Duran (2-for-5 with a homer and a double) and Connor Wong (2-for-4 with a homer) have found significant success against him, boasting impressive power numbers in a small sample size against the O’s right-hander.

Baltimore Orioles Career Statistics vs Lucas Giolito

PitcherABH2B3BHRRBIBBKAVGOBPSLGOPS
D. Carlson71000103.143.125.143.268
G. Henderson20000011.000.333.000.333
D. Johnson30000003.000.000.000.000
V. Machin20000010.000.333.000.333
R. Mountcastle62000101.333.333.333.667
Totals203000228.150.217.150.367

Giolito has allowed just three hits to the Orioles’ batters in 20 at-bats, and all three were singles. He’s piled up eight strikeouts while giving up two walks. Altogether, the Baltimore hitters have a miniscule .150 average and .367 OPS against the 31-year-old righty.

Public Betting Splits: Boston Red Sox vs Baltimore Orioles

Public sentiment is heavily skewed towards the visitors, with 74.6% of moneyline bets and 77.0% of runline bets backing the Red Sox. This overwhelming public support is driven by Boston’s recent form and the Orioles’ injury woes.

Interestingly, there is a sharp-money indicator suggesting professional bettors are finding value on Baltimore, creating a classic “Pros-vs-Joes” scenario on the moneyline.

For the total, the public is leaning toward the over (59.5% of bets), and the sharp-money discrepancy also favors the over, indicating that both casual and professional bettors expect runs to be scored tonight.

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Sascha Paruk
Sascha Paruk

Managing Editor

Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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