Red Sox vs Reds Odds, Lines & Spread (Sep. 20)
By Robert Duff in MLB Baseball
Updated: February 20, 2025 at 11:56 am ESTPublished:
- The Boston Red Sox are slight -115 away favorites over the Cincinnati Reds in the opener of a two-game inter-league series on Tuesday, September 20
- Cincinnati and the Red Sox split two games played in July at Boston
- Get the Red Sox vs Reds picks and odds, below
The Cincinnati Reds (58-89, 29-43 home) once beat the Boston Red Sox (71-75, 34-38 away) in a memorable seven-game World Series in 1975. Neither club will be getting a sniff of the postseason this year, however.
The Red Sox and Reds are playing out the string, and that includes a two-game inter-league series beginning Tuesday.
Boston is 13-2 straight up in the last 15 games against the Reds. The Red Sox are 7-0 straight up in their last seven games at Cincinnati.
Oddsmakers are leaning slightly toward the Red Sox in the betting line on this game. Boston is a -115 road favorite. The Reds are set as -105 home underdogs.
Red Sox vs Reds Odds
| Team | Moneyline | Runline | Total |
|---|---|---|---|
| Boston Red Sox | -115 | -1.5 (+143) | O 8.5 (-110) |
| Cincinnati Reds | -105 | +1.5 (-170) | U 8.5 (-110) |
Odds as of September 19 at Caesars Sportsbook. Get Caesars Sportsbook bonus code.
At moneyline odds of -115, the Red Sox have an implied probability of victory of 53.49% in the MLB betting line. A successful $10 wager on Boston would create a payout of $18.70.
The MLB lineups will be set for the first pitch at Great American Ball Park at 6:40 pm ET on Tuesday, September 20. The weather forecast is calling for cloudy skies with 1 mph wind and a temperature of 86 degrees.
MLB betting trends are showing that 53% of the public betting splits on both the moneyline and runline bets are backing the Red Sox. There’s also 53% of public money going with the under in the total.
Red Sox vs Reds Probable Pitchers
Red Sox rookie right-hander Brayan Bello tasted victory for the first time as an MLB pitcher on September 3. Working a season-high six innings, he didn’t allow a run and surrendered just three hits en route to a 5-3 win over the Texas Rangers.
https://twitter.com/craig_teed/status/1570251355268288512?s=20&t=-0W9QnIl5QD1psCnXU5V6Q
However, he’s lost his next two starts against AL rivals Baltimore and the New York Yankees. Bello has struck out 27 batters over his last 25.1 innings pitched.
Bello is 0-2 with a 7.07 ERA in four away appearances this season, including three starts. His WHIP on the road is 1.90 and his strikeouts to walks ratio is 1.60. He’ll be facing the Reds for the first time as an MLB pitcher.
Bello vs Lodolo Stats
| 1-6 | Record | 4-6 |
| 5.10 | ERA | 3.81 |
| 3.77 | xERA | 3.63 |
| 1.70 | WHIP | 1.27 |
| 2.00 | SO/W Ratio | 3.77 |
Reds left-hander Nick Lodolo appears to have rediscovered his mojo. He went 0-2 with a 4.40 ERA in August. That came on the heels of a July in which he was 2-1 with a 3.42 ERA.
Nick Lodolo is the first Red and fourth LHP in MLB since 1901 with 11+ strikeouts and 0 walks in consecutive starts.
(h/t @jluckhaupt) pic.twitter.com/iShzluxnUl
— Cincinnati Reds (@Reds) September 14, 2022
So far in September, the rookie southpaw is 1-1 with a 2.21 ERA. Lodolo has struck out 31 against one walk in just 20.1 innings of work. He’s punched out 11 hitters in each of his last two starts.
Lodolo is 3-3 with a 2.77 ERA in 10 home starts. He’ll be facing the Red Sox for the first time as an MLB hurler.
Batting Average vs Starting Pitchers
Boston’s Yu Chang is the only batter on either club who’s faced the opposing starting pitcher previously in the big leagues. Chang is 0-for-3 against Lodolo.
In head-to-head action this season, Cincinnati’s Matt Reynolds is hitting .500 (3-for-6) against the Red Sox. Aristides Aquino is 2-for-6 (.333).
DUGIE TIES IT UP WITH A BOMB!!! Alex Verdugo’s home run swing is so freaking nice. https://t.co/E8BKK2kuKE
— Boston Sports Gordo (@BOSSportsGordo) August 7, 2022
For Boston, Alex Verdugo is 3-for-7 (.429) with three RBI off of Cincinnati pitching. Rafael Devers is 3-for-8 (.375). Xander Bogaerts is 2-for-6 (.333) with an RBI.
Red Sox vs Reds Prediction
Boston completed a 2-3 homestead on the heels of a 2-4 road trip. Cincinnati is 2-3 SU in the last five games, but 2-9 SU over the past 11 games.
Both Lodolo and Bello are giving off indications that a bright future is ahead for them as MLB pitchers. At this stage of their progression, it would appear that Lodolo is slightly in front of Bello along the learning curve.
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Pick:Â Cincinnati Reds ML (-105)
Sports Writer
An industry veteran, Bob literally taught the course on the history of sports at Elder College. He has worked as a Sports Columnist for Postmedia, appeared as a guest on several radio stations, was the Vice President of the Society For International Hockey Research in Ontario, and written 25 books.
