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Twins vs Royals Odds, Lines & Picks (Sep. 22)

Robert Duff

by Robert Duff in MLB Baseball

Updated Sep 21, 2022 · 8:32 PM PDT

Twins vs Royals odds
Sep 20, 2022; Kansas City, Missouri, USA; Kansas City Royals left fielder MJ Melendez (1) is tagged out at home by Minnesota Twins catcher Gary Sanchez (24) during the seventh inning at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-USA TODAY Sports
  • The Minnesota is a -130 road favorite over Kansas City in the Twins vs Royals odds on Thursday, September 22
  • Minnesota is 4-1 straight up in the past five games at Kansas City
  • Overall, the Twins hold an 8-2 SU edge over the Royals in the last 10 games

A dismal road record has doomed the Minnesota Twins (73-75, 30-43 away) this season, but for the Kansas City Royals (59-89, 35-41 home), their troubles extend to both home and away games.

Only the Royals (24) and Detroit Tigers have won fewer road games this season among American League than the Twins. Minnesota’s 34-43 road mark against the runline is third-worst in MLB.

Regardless, it’s the Twins who are -130 road favorites for the conclusion of this three-game series between AL Central rivals.

Twins vs Royals Odds

Team Moneyline Runline Total
Minnesota Twins -130 -1.5 (-130) O 8 (-115)
Kansas City Royals +110 +1.5 (-155) U 8 (-105)

Odds as of September 21 at Caesars Sportsbook. Get Caesars Sportsbook bonus code.

The Royals are 37-39 ATR as a home team during the 2022 campaign.

At moneyline odds of -130, the Twins have an implied probability of victory of 56.52% in the MLB betting line. A successful $10 wager on Minnesota would create a payout of $17.70.



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The MLB lineups will be set for the first pitch at Kauffman Stadium at 2:10 pm ET on Thursday, September 22. The weather forecast is calling for cloudy skies with 5 mph wind and a temperature of 67 degrees.

MLB betting trends are showing that 57% of the public betting splits on both the moneyline are supporting Minnesota. However, only 1% of runline bets are backing the Twins. There’s also 57% of public money going with the over in the total.

Twins vs Royals Probable Pitchers

Twins rookie right-hander Josh Winder will be making his 13th MLB appearance and eighth start as he goes to the bump to face the Royals. Recalled to MLB on September 12, he’s allowed six earned runs and three home runs in two starts covering 8.2 innings of work since returning to The Show.

Winder won his first two MLB decisions, then he lost his next two. He followed that with two more wins, and has since absorbed two losses. He rates in the bottom 7% of MLB hurlers in strikeout percentage (15.4).

Winder will be making his first career start at Kauffman Stadium. In fact, he’s facing the Royals for the first time as a big-league pitcher.

Winder vs Heasley Stats

Josh Winder
Jonathan Heasley
4-4 Record 3-8
4.17 ERA 5.09
4.48 xERA 5.44
1.25 WHIP 1.51
2.19 SO/W Ratio 1.48

Royals right-hander Jonathan Heasley rates among the bottom 6% of MLB pitchers in xERA (5.44) and xwOBA (.356). He’s among the lower 7% in exit velocity (90.5) and hard hit percentage (45.1). Heasley finds himself in the bottom 8% in strikeout percentage (15.7) and wOBA (.357).  As well, he’s in the bottom 10% of pitchers in xSLG (.456).


The righty is 1-0 against the Twins. He made his only start against Minnesota on October 1, 2021. Heasley worked 5.1 innings and allowed four earned runs in an 11-6 KC victory. He’s 3-7 with a 6.66 ERA in 11 career starts at Kauffman Stadium.

Batting Average vs Starting Pitchers

Minnesota’s Luis Arraez and Nick Gordon are the only batters on either club who’ve faced the opposing starting pitcher previously in the big leagues. Arraez is 0-for-3 against Heasley. Gordon is 0-for-2.

Kansas City’s Salvador Perez (22) and Bobby Witt Jr (20) have both reached the 20-homer plateau this season.

For Minnesota, Arraez is batting .314. Carlos Correa has clouted 21 home runs.

Twins vs Royals Prediction

Minnesota is skidding to the finish line. Entering play Wednesday, the Twins are 6-13 SU in September. Three of those wins came in a home sweep of the Royals, though. Minnesota is 12-5 SU against Kansas City this season and 35-30 SU when facing AL Central opponents.

The Royals are 40-70 against right-handed starters this season. Kansas City has hit an AL-leading 35 triples.

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Pick: Minnesota Twins ML (-130)


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