Bulls vs Pistons Picks, Prediction, Betting Splits & Odds

• The Pistons remain without Tobias Harris and Jaden Ivey when they host the Bulls on Wednesday night
• Game script points to high-usage for Cade Cunningham as a scorer rather than a facilitator, if he plays
• See my top Bulls vs Pistons picks and player props to bet, along with the updated CHI vs DET odds

Central Division rivals meet on Wednesday when the Chicago Bulls (6-4, 1-3 away, 7-3 ATS, 6-4 O/U) travel to face the Detroit Pistons (9-2, 4-1 home, 7-4 ATS, 5-6 O/U) at Little Caesars Arena at 7:00 pm ET. CHSN and FDSDET will carry the broadcasts locally.

Already without key contributors Tobias Harris, Ausar Thompson, and Jaden Ivey, the Pistons got unwelcome news this morning when Cade Cunningham (hip) missed shootaround. Detroit’s star guard, who sits sixth in the NBA MVP odds, is officially listed as a game-time decision.

Chicago has plenty of injury concerns of their own, with Josh Giddey (ankle) listed as a GTD, and Coby White (calf) and Zach Collins (wrist) out. But Detroit is in considerably worse shape, which has led the Bulls vs Pistons odds to flip, slightly favoring Chicago as of noon ET on gameday after Detroit opened as a 2.5-point home favorite.

Below, I have set out my three favorite Bulls vs Pistons picks – ATS, O/U, and a player prop bet – followed by the current Bulls vs Pistons odds and public-betting splits.

Go to: PICKS || ODDS || BETTING SPLITS

Bulls vs Pistons Prediction & Betting Picks

• ATS Pick: Bulls -1 (-110) at Fanatics
• O/U Pick: Under 234.5 (-105) at ESPN
• Player-Prop Pick: Cunningham Under 9.5 Assists (+110) at DraftKings

This matchup pits a powerful home-court trend against a harsh injury reality. While the Pistons have been formidable at Little Caesars Arena, posting an impressive 5-1 SU record at home this season, they enter Wednesday night severely compromised in terms of personnel. The absence of key offensive weapons Tobias Harris and Jaden Ivey was bad enough, as both players represent crucial secondary scoring options that allow Cade Cunningham to operate with breathing room.

This morning’s news that Cunningham missed shootaround and will be a GTD to even suit up caused the line to cross zero. This significant line movement toward the healthier Bulls squad signals sharp money recognizing the value in the road team’s situation.

Detroit’s home dominance becomes less impressive when examined against quality competition. The Pistons have lost their last five games at home against opponents with a winning record, revealing their vulnerability when facing teams with playoff aspirations. Chicago may not be a juggernaut, but they possess enough offensive firepower led by Giddey (21.4 PPG, 9.6 RPG, 9.3 APG) and Nikola Vučević (17.1 PPG, 10.3 RPG, 3.7 APG) to exploit a depleted roster.

This total assumes both teams will roughly maintain their season-long offensive efficiency, but Detroit’s reality is far different. The Bulls show a strong road over trend with nine of their last 12 road games going over, but the Pistons’ situation overrides this pattern. With their primary and secondary scorers either sidelined or diminished, Detroit’s contribution to the total will be significantly hampered. The over has hit in just one of the Pistons’ last five home games against opponents with a winning record, indicating their struggles to generate offense against quality competition.

Even if Cunningham plays, his primary passing targets will still be unavailable. This will force the point guard into a larger scoring role. Chicago’s defense can focus entirely on Cunningham knowing he lacks reliable finishers, creating a scenario where his usage rate skyrockets but his assist opportunities dwindle.

CHI Bulls vs DET Pistons Betting Lines

As of 1:15 pm ET, the Bulls had become 1.0 to 1.5-point road favorites, with their moneyline price now -105 (bet365) or shorter. The Pistons had faded as long as +110 to win straight-up (Caesars Sportsbook).

The game total still showed a one-point range from 234.5 to 235.5, with DraftKings offering the best under number and bet365 offering the best over number.

The odds in the table will update automatically to reflect the best-available price for each market if the NBA odds move over the course of the day.

CHI vs DET Public-Betting Splits

Wednesday’s NBA public betting splits reveal a clear consensus favoring the home team and the over, but the money distribution tells a more nuanced story that suggests professional bettors see value in the contrarian play.

Moneyline
The most telling indicator lies in the moneyline market. While an overwhelming 74.2% of all bets have been placed on the Pistons to win outright, they command only 51.0% of the total money wagered. The underdog Bulls are attracting 49.0% of the handle from just 25.8% of the tickets, creating a near-even split in actual dollars at risk. This pattern typically indicates that larger, more sophisticated wagers are backing the road team.

Spread Market
Public sentiment aligns more consistently on the spread, with Detroit attracting 67.6% of the bets and 67.1% of the handle. This shows widespread confidence in the home team’s ability to cover despite their injury concerns.

Totals Market
Bettors are overwhelmingly expecting a high-scoring affair, with 81.4% of tickets and 83.6% of the money backing the over. This massive public support for the over, combined with Detroit’s offensive limitations, creates significant value in the under.

The public’s heavy investment in the Pistons and the over presents a prime fade-the-public opportunity for bettors who recognize that Chicago’s health advantage and Detroit’s offensive absences are being undervalued by the recreational betting market.