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2020 College Football Week 6 Picks Against the Spread

Blair Johnson

by Blair Johnson in College Football

Updated Mar 4, 2021 · 2:21 PM PST

Miami quarterback D'Eriq King handing off the ball to running back Donald Chaney Jr. during a game.
Miami quarterback D'Eriq King (1) hands off to running back Donald Chaney Jr. during the second quarter of the team's NCAA college football game against Duke on Saturday, Dec. 5, 2020, in Durham, N.C. (Nell Redmond/Pool Photo via AP)
  • See picks against the spread for the biggest games on the Week 6 College Football slate
  • No. 7 Miami visiting No. 1 Clemson is the marquee matchup, but a Red River Showdown featuring desperate teams and No 14 Tennessee visiting No. 3 Georgia are also on the slate
  • Read below for the picks and odds for Week 6 of the college football season

Week 6 of the college football season gets underway Thursday, but the marquee matchup is a big one: No. 1 Clemson is hosting No. 7 Miami in an ACC showdown that offers the Hurricanes a chance to make a statement on the national stage.

Meanwhile, the Red River Showdown pits a desperate Oklahoma and Texas against each other at the Cotton Bowl, while No. 14 Tennessee faces off against No. 3 Georgia between the hedge.

Here are my three favorites ATS picks for Week 6.

#7 Miami vs #1 Clemson Odds

Team Spread Moneyline Total
Miami Hurricanes +14.5 (-114) +440 0 63.5 (-106)
Clemson Tigers -14.5 (-108) -650 U 63.5 (-114)

All odds taken Oct. 8th on FanDuel

Pick #1: The ‘Canes Will Hang With Clemson

Clemson beat Virginia 41-23 in Week 5 as Trevor Lawrence and Travis Etienne led the top-ranked team in the land to another victory. The projected No. 1 pick in the 2020 NFL Draft threw for 329 yards and three touchdowns, while Etienne matched a mark set by Tim Tebow in the win.

The senior running back’s 187 all-purpose yard, two touchdown performance marked the 38th game he’s hit pay-dirt at least once, matching Tebow and Louisiana Tech’s Kenneth Dixon’s all-time mark.


But the Tigers were less than dominant. A slow start coming off a Week 4 bye saw the No. 1 team holding only a 3-0 lead before Etienne’s 16-yard score late in the first quarter. The Cavs drew to within 27-17 midway through the third quarter before Dabo Swinney’s group pulled away.

Miami will be coming off a bye heading into South Carolina after demolishing in-state rival Florida State 52-10 in Week 4.

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Houston transfer quarterback D’Eriq King has Manny Diaz’s program off to a 3-0 start for the first time since 2017 and has yet to throw an interception this season. In fact, he compares favorably to Lawrence on third downs.

But what was truly impressive in the highest-scoring victory over Florida State in series history was the ‘Canes’ defense. The unit racked up six sacks, 13 tackles for loss and three interceptions against the ‘Noles.

Do I expect a repeat of that performance Saturday? Absolutely not. While Brent Venables’ defense will no doubt slow King down, the two-touchdown spread feels a little too big.

Pick: Miami +14.5 (-114)

#22 Texas vs Oklahoma Odds

Team Spread Moneyline Total
Texas Longhorns +2.5 (-110) +112 0 72.5 (-110)
Oklahoma Sooners -2.5 (-110) -138 U 72.5 (-110)

Pick #2: Sooners Bounce Back Against the Longhorns

The Red River Showdown may not have the luster of years past – it’s the first time since 1999 that neither team is ranked in the Top 20 entering the game – but the contest pitting Oklahoma against Texas is still intriguing. That’s because both teams are in desperate need of a win.

The Sooners have dropped back-to-back regular season games for the first time since that same 1999 season, while Texas is coming off a home loss to unranked TCU. Oklahoma has a number of issues, partially summarized here.

Even with a freshman quarterback and a porous defense, the Sooners are still somehow co-favorites to win the Big 12 title.

History seems to favor Texas in this spot. But I simply don’t trust Sam Ehlinger and Tom Herman to send Oklahoma to a third straight defeat. I expect a shootout, so the over is a good bet. I like Lincoln Riley’s squad to get back on the winning track at the Cotton Bowl.

Pick: Oklahoma -2.5 (-110)

#14 Tennessee vs #3 Georgia Odds

Team Spread Moneyline Total
Tennessee Volunteers +12.5 (-110) +440 0 43.5 (-108)
Georgia Bulldogs -12.5 (-110) -650 U 43.5 (-112)

Pick #3: Bulldogs Keep Barking

Believe it or not, Tennessee has beaten Georgia twice (2015 and 2016) in the last five years. Those victories seem like a distant memory to Volunteer fans after three straight losses to the Dawgs by an average outcome of 41-9.

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Jeremy Pruitt’s program comes into this year’s outing as nearly two-touchdown underdogs. The Vols are 2-0 following wins over South Carolina and Missouri, but Georgia is a significant step up in competition over the Gamecocks and Tigers.

UGA has handled Arkansas and Auburn with relative ease, winning by 27, and 21 points, respectively. UT feels like its somewhere between the Razorbacks and Tigers – so I’m predicting the Dawgs win by roughly 20 points.

Kirby Smart’s team has high expectations in 2020 and I don’t expect an upstart Tennessee to give it much of a problem.

Pick: Georgia -12.5 (-110)

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