Los Angeles Chargers vs Las Vegas Raiders Odds, Props, Picks & Predictions (MNF)
By Sascha Paruk in NFL News
Published:
- Justin Herbert and the Los Angeles Chargers visit Geno Smith and the Las Vegas Raiders on MNF
- The Chargers are 8-2 ATS in their last ten as favorites, while the Raiders are 1-11 SU in their last 12 as underdogs
- See the Raiders vs Chargers picks, predictions, and latest odds
An early-season battle for AFC West supremacy unfolds under the bright lights of Las Vegas as the Raiders (1-0, 1-0 away, 1-0 ATS, 0-1 O/U) host the Los Angeles Chargers (1-0, 0-0 home, 1-0 ATS, 1-0 O/U) at Allegiant Stadium in the second leg of a MNF doubleheader at 7:00 pm PT/10:00 pm ET.
After an impressive 27-21 victory over the three-time defending AFC-champion Chiefs in Week 1, the Chargers are 3.5-point road chalk at the Raiders in the MNF odds.
Below, find an interactive table with up-to-the-minute odds, plus my favorite Chargers vs Raiders picks and predictions.
Los Angeles Chargers vs Las Vegas Raiders Odds
At the time of writing (10:36 am ET), the best available LAC moneyline was -180 at FanDuel, while the Raiders were as long as +162 at Caesars. The best spread option for Charger bettors was -3.0 (-120) at FanDuel. The best ATS odds for Las Vegas backers was +3.5 (-115) at bet365. The total was 46.5 across the board with only slight variations in price.

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LAC vs LV Odds Movement
The only notable movement since the Week 2 odds opened is on the game total. After opening at just 44.5 (-110 each way), the O/U has been bet up two full points, and may be going even higher at some books.
The expectation for a high-scoring game is somewhat logical given that both offenses ranked in the top ten in passing yards in Week 1 while both defenses ranked in the bottom third against the pass.
The Chargers have also been an over machine recently, with the total going over in each of their last six games.
Key Matchups to Watch in Chargers vs Raiders
Herbert vs Las Vegas Pass Defense
Justin Herbert comes into this game with a sizzling 131.7 passer rating after throwing for 304 yards and three TDs with no interceptions in Week 1 against an elite Kansas City defense. He faces a Las Vegas Raiders secondary that allowed 276 yards to a Patriots passing game that is unlikely to finish the season in the top-half of the league. This is a massive mismatch favoring the Chargers.
Geno Smith was also effective, posting a 102.8 rating against New England, but the Los Angeles Chargers defense generated eight QB hits against KC and is better equipped to apply pressure.
Raiders Running Game vs Chargers Run Defense
The Las Vegas Raiders’ ground game was non-existent in Week 1, managing just 56 yards at a paltry 2.3 yards per carry. They’ll find it tough sledding against a Chargers run defense that allowed just 41 yards to Kansas City running backs.
Chargers vs Raiders Player Props
NFL props as of September 15 at DraftKings.
Justin Herbert’s passing yards prop of 252.5 is a touch low. He threw for 318 yards in Week 1 and now faces a Raiders pass defense that allowed 276 yards through the air to Drake Maye and the Patriots.
Geno Smith’s line is set at 242.5, well below his 333-yard performance last week, but he faces a tougher secondary and a more potent pass rush.
Ladd McConkey’s receiving line of 73.5 yards is intriguing against a porous Raiders secondary. Brock Bowers’ receptions prop of 6.5 is ambitious, but he’s clearly a focal point of the new offense.
Ashton Jeanty’s rushing prop of 68.5 is high given the team’s struggles on the ground and a matchup against a solid run defense.
Los Angeles Chargers vs Las Vegas Raiders Picks & Prediction
- Against the Spread: Los Angeles Chargers -3.0 (-120) at FanDuel
- Over/Under: Over 46.5 (-105) at FanDuel
- Player Prop: Justin Herbert over 252.5 passing yards (-113) at DraftKings
Everything points toward the Los Angeles Chargers in this AFC West showdown. The advantages at the most critical positions are stark. Justin Herbert is playing at an elite level and faces a secondary that was picked apart in Week 1. The Chargers’ pass rush, led by Joey Bosa, is poised to exploit a Raiders offensive line that is already dealing with an injury at center.
While Geno Smith was efficient in his debut, he will be under far more duress than he was against New England, which will disrupt the timing of the Raiders’ vertical passing attack.
The betting trends also paint a lopsided picture. The Chargers are a remarkable 8-2 against the spread in their last ten games as a favorite and 5-1 ATS in their last six road games.
Conversely, the Raiders have been a financial pitfall for bettors, going 1-11 straight-up against teams with a winning record and losing their last five games outright as a home underdog.
The Chargers’ offense has also been a catalyst for high-scoring games, with the over hitting in each of their last six contests. With two suspect secondaries on the field, that trend is likely to continue.
My only hesitation is potential fatigue from the Chargers’ Week 1 game in Brazil, but their dominant performance and the extra two days of rest should mitigate that concern. Trust the superior quarterback and the stronger team on both sides of the ball.
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The sports and sports betting data in this article was gathered with the assistance of AI that is connected to Sportradar’s database.
Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.