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Opening Panthers vs Buccaneers Odds for Week 18

Sascha Paruk

By Sascha Paruk in NFL News

Published:


Carolina Panthers quarterback Bryce Young in the pocket
Dec 21, 2025; Charlotte, North Carolina, USA; Carolina Panthers quarterback Bryce Young (9) drops to throw during the second half against the Tampa Bay Buccaneers at Bank of America Stadium. Mandatory Credit: Jim Dedmon-Imagn Images
  • The Panthers will visit the Buccaneers in Week 18 with the NFC South title on the line
  • The Panthers won the first meeting of the season two weeks ago
  • See the opening Panthers vs Buccaneers odds for Week 18

The Carolina Panthers (8-8, away) and Tampa Bay Buccaneers (7-9, 3-5 home) both lost in Week 17, which has set-up a winner-take-all battle for the division title in Week 18.

Kickoff is tentatively scheduled for 1:00 pm ET but that is subject to change. The table below lists the opening Panthers vs Buccaneers odds for Week 18.

Panthers vs Buccaneers Odds (Week 18)

MarketCarolinaTampa Bay
Spread+3.5 (-110)-3.5 (-110)
Moneyline+165-200
TotalO 44.0 (-110)U 44.0 (-110)

The Buccaneers have opened as 3.5-point home chalk with both teams priced at -110 to cover the spread.

On the moneyline, Tampa Bay has opened at -200, which carries a 66.7% implied win probability. The Panthers come back as +165 underdogs (37.74% implied win probability).

The total is sitting at 44.0 with -110 odds both ways. The first meeting in Week 16 ended in a 23-20 Panther victory in Carolina.

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Odds as of 4:35 pm ET at DraftKings. Download the top NFL betting apps for the 2026 postseason.

Ideal weather conditions are forecasted for Tampa Bay on Sunday, Jan. 4. Meteorologists expect a mix of sun and clouds with a high of 72° and minimal wind.

Tampa Bay out-gained Carolina 296 to 275 during their Week 16 setback. The Bucs managed 169 rush yards at 5.1 yards per carry, but just 127 pass yards at 4.9 yards per attempt.

Buccaneers Have Owned Panthers in Tampa

Week 16 notwithstanding, this division rivalry has been one-sided of late. Carolina’s Week 16 victory ended a five-game head-to-head losing streak, and marked Bryce Young’s first career victory over the Bucs.

The Bucs have won nine of the last 11, overall. Carolina hasn’t won in Tampa since 2017 when Cam Newton was still at the helm.

Bookmark SBD’s NFL odds page to see up-to-the-minute lines for every regular-season and playoff game.

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Sascha Paruk
Sascha Paruk

Managing Editor

Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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