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Opening NFL Week 13 Odds – Spread, Total, Moneyline for All 16 Games

Sascha Paruk

By Sascha Paruk in NFL News

Published:


Detroit Lions wide receiver Kalif Raymond eludes a tackle by Green Bay Packers cornerback Bo Melton
Green Bay Packers cornerback Bo Melton (16) dives after Detroit Lions wide receiver Kalif Raymond (11) on a punt return on Sunday, September 7, 2025, at Lambeau Field in Green Bay, Wis. The Packers won the game, 27-13. Tork Mason/USA TODAY NETWORK-Wisconsin
  • The NFL Week 13 odds are out including the spread for all three Thanksgiving games and Black Friday
  • The Bears and Eagles will meet on Black Friday in Philadelphia
  • See the opening NFL Week 13 odds for all 16 games on the slate

It’s Thanksgiving week in the NFL, meaning bettors will be treated to a three-game slate on Thursday – Packers vs Lions, Chiefs vs Cowboys, Bengals vs Ravens – plus a Black Friday game between the Bears and Eagles.

In the table below, I have set out the opening NFL Week 13 odds for all 16 games (no teams are on bye). Bookmark SBD’s NFL odds page to see how the lines move over the course of the week, plus our NFL public betting splits to see how the public is betting each game.

NFL Week 13 Odds

TeamSpreadMoneylineTotal
GB Packers+3 (-110)+145O 48.5 (-110)
DET Lions-3 (-110)-162U 48.5 (-110)
TeamSpreadMoneylineTotal
KC Chiefs-3.5 (-110)-186O 51.5 (-110)
DAL Cowboys+3.5 (-110)+160U 51.5 (-110)
TeamSpreadMoneylineTotal
CIN Bengals+7.5 (-105)+350O 52.5 (-110)
BAL Ravens-7.5 (-115)-450U 52.5 (-110)
TeamSpreadMoneylineTotal
CHI Bears.5 (-110)O .5 (-110)
PHI Eagles.5 (-110)U .5 (-110)
TeamSpreadMoneylineTotal
JAX Jaguars.5 (-110)O .5 (-110)
TEN Titans.5 (-110)U .5 (-110)
TeamSpreadMoneylineTotal
ATL Falcons.5 (-110)O .5 (-110)
NY Jets.5 (-110)U .5 (-110)
TeamSpreadMoneylineTotal
LA Rams-9.5 (-110)-450O 45.5 (-110)
CAR Panthers+9.5 (-110)+350U 45.5 (-110)
TeamSpreadMoneylineTotal
NO Saints+4.5 (-110)+170O 42.5 (-110)
MIA Dolphins-4.5 (-110)-205U 42.5 (-110)
TeamSpreadMoneylineTotal
ARI Cardinals+6.5 (-115)+230O 49.5 (-110)
TB Buccaneers-6.5 (-105)-280U 49.5 (-110)
TeamSpreadMoneylineTotal
SF 49ers -6.5 (-110)-305O 41.5 (-110)
CLE Browns+6.5 (-110)+245U 41.5 (-110)
TeamSpreadMoneylineTotal
HOU Texans.5 (-110)O .5 (-110)
IND Colts.5 (-110)U .5 (-110)
TeamSpreadMoneylineTotal
MIN Vikings.5 (-110)O .5 (-110)
SEA Seahawks.5 (-110)U .5 (-110)
TeamSpreadMoneylineTotal
BUF Bills.5 (-110)O .5 (-110)
PIT Steelers.5 (-110)U .5 (-110)
TeamSpreadMoneylineTotal
LV Raiders+8.5 (-110)+325O 42.5 (-110)
LA Chargers-8.5 (-110)-425U 42.5 (-110)
TeamSpreadMoneylineTotal
DEN Broncos-6.5 (-115)-300O 43.5 (-110)
WSH Commanders+6.5 (-105)+240U 43.5 (-110)
TeamSpreadMoneylineTotal
NY Giants.5 (-110)O .5 (-110)
NE Patriots.5 (-110)U .5 (-110)

The biggest spread on the board in Week 13 is the LA Rams (9-2) laying 9.5 points on the road against the Carolina Panthers (6-5). The highest total is 52.5 in Bengals vs Ravens. while the lowest total is just 41.5 in 49ers vs Browns.

Odds as of Nov. 23rd at DraftKings, FanDuel, and bet365. Claim the latest pre-registration offers from bet365 Missouri.

Opening Packers vs Lions Odds

TBD

Opening Chiefs vs Cowboys Odds

The Kansas City Chiefs (6-5) might have saved their season earlier today with a 23-20 comeback win over the Colts. KC is still on the outside looking in when it comes to the updated NFL playoff bracket but falling below .500 at this stage of the season might have been a death sentence. Kansas City has now opened as a road favorite at the Dallas Cowboys on Thanksgiving.

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Sascha Paruk
Sascha Paruk

Managing Editor

Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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