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Opening NFL Week 18 Odds – Spread, Total, Moneyline for Final Week

Sascha Paruk

By Sascha Paruk in NFL News

Published:


Tampa Bay Buccaneers quarterback Baker Mayfield runs with the ball against the Carolina Panthers
Dec 21, 2025; Charlotte, North Carolina, USA; Tampa Bay Buccaneers quarterback Baker Mayfield (6) runs during the second half against the Carolina Panthers at Bank of America Stadium. Mandatory Credit: Jim Dedmon-Imagn Images
  • The NFL Week 18 odds have been posted
  • Several teams are expected to rest starters in the final week of the season
  • See the NFL Week 18 odds, including the spread, total, and moneyline for all 16 games on the schedule

As we enter the final week of the NFL regular season, some teams are battling for postseason berths/positioning, while others are playing out the string. The NFL Week 18 odds are usually the slowest to come out due to the potential for starters to be stapled to the bench.

But the lines for several games have already been posted, and the rest will follow eventually. The table below lists the opening NFL Week 18 odds for all games currently on the board. More lines will be added as they become available. There are no TNF odds or MNF odds in Week 18 as all 16 games will take place on Sunday, Jan. 4th.

NFL Week 18 Odds

TeamSpreadMoneylineTotal
CAR Panthers+3.5 (-105)+165O 44.0 (-110)
TB Buccaneers-3.5 (-115)-200U 44.0 (-110)
TeamSpreadMoneylineTotal
BAL Ravens-3.0 (-110)-162O 43.5 (-110)
PIT Steelers+3.0 (-110)+136U 43.5 (-110)
TeamSpreadMoneylineTotal
MIA DolphinsTBDTBDTBD
NE PatriotsTBDTBDTBD
TeamSpreadMoneylineTotal
GB PackersTBDTBDTBD
MIN VikingsTBDTBDTBD
TeamSpreadMoneylineTotal
TEN TitansTBDTBDTBD
JAX JaguarsTBD-TBDTBD
TeamSpreadMoneylineTotal
ARI CardinalsTBDTBDTBD
LA RamsTBDTBDTBD
TeamSpreadMoneylineTotal
DET LionsTBDTBDTBD
CHI BearsTBDTBDTBD
TeamSpreadMoneylineTotal
IND ColtsTBDTBDTBD
HOU TexansTBDTBDTBD
TeamSpreadMoneylineTotal
WSH CommandersTBDTBDTBD
PHI EaglesTBDTBDTBD
TeamSpreadMoneylineTotal
DAL CowboysTBDTBDTBD
NY GiantsTBDTBDTBD
TeamSpreadMoneylineTotal
CLE BrownsTBDTBDTBD
CIN BengalsTBDTBDTBD
TeamSpreadMoneylineTotal
NO SaintsTBDTBDTBD
ATL FalconsTBDTBDTBD
TeamSpreadMoneylineTotal
NY JetsTBDTBDTBD
BUF BillsTBDTBDTBD
TeamSpreadMoneylineTotal
KC ChiefsTBDTBDTBD
LV RaidersTBDTBDTBD
TeamSpreadMoneylineTotal
LA ChargersTBDTBDTBD
DEN BroncosTBDTBDTBD
TeamSpreadMoneylineTotal
SEA SeahawksTBDTBDTBD
SF 49ersTBDTBDTBD

Odds as of Dec. 28 at bet365, DraftKings, and FanDuel. Download the top NFL betting apps for the 2026 playoffs.

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Opening Panthers vs Buccaneers Odds

The Panthers and Buccaneers both lost in Week 17, setting up a winner-take-all battle for the NFC South title in Week 18. Like the AFC North, only the division-winner is going to make the postseason.

Tampa Bay has opened as a 3.5-point home favorite. The Panthers took the first meeting between the teams (23-20) at home just one week ago.

Opening Ravens vs Steelers Odds

Pittsburgh’s loss at Cleveland on Sunday afternoon means that the Week 18 tilt between the Ravens and Steelers will be for the AFC North title and the division’s lone berth in the NFL playoff bracket.

Despite Pittsburgh having home-field advantage, Baltimore has opened as a three-point road favorite. The Steelers won 27-22 in Baltimore back in Week 14 as 5.5-point road underdogs.

Opening Seahawks vs 49ers Odds

TBD

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Sascha Paruk
Sascha Paruk

Managing Editor

Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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