MLS Week 25 Odds & Picks: DC United vs Chicago Fire, Toronto FC vs Inter Miami & More

By Ryan Metivier in Soccer News
Published:

- MLS Week 25 features 11 games from September 14-15, 2021
- Will Colorado keep winning? Can Toronto FC snap their winless skid?
- Read on for the odds and our best bets from MLS Week 25
MLS Week 25 kicks off midweek with three matches on Tuesday and eight more on Wednesday. New England is leading the East and is on pace to break the single-season record for most regular season points. While Seattle has now regained their spot of first in the West after this past weekend’s win.
As far as current steaks entering MLS Week 25, the Colorado Rapids are undefeated in eight matches, while Toronto has failed to win over their past eight.
Let’s look ahead to the odds and best bets from the MLS Week 25 schedule below.
MLS Week 25 Odds
Matchup | Home | Draw | Away |
---|---|---|---|
Columbus Crew vs New York Red Bulls | +130 | +245 | +215 |
New York City FC vs FC Dallas | -235 | +400 | +600 |
Toronto FC vs Inter Miami | +135 | +235 | +215 |
Atlanta United vs FC Cincinnati | -175 | +340 | +475 |
DC United vs Chicago Fire | -140 | +300 | +370 |
Orlando City SC vs CF Montreal | -140 | +295 | +380 |
Sporting Kansas City vs Minnesota United | -115 | +290 | +300 |
Austin FC vs Los Angeles FC | +190 | +260 | +140 |
Portland Timbers vs Colorado Rapids | +150 | +255 | +175 |
LA Galaxy vs Houston Dynamo | -145 | +320 | +370 |
San Jose Earthquakes vs Real Salt Lake | +120 | +265 | +225 |
Odds as of Sept 13 at DraftKings
Toronto FC vs Inter Miami Prediction
One of three games to kick off midweek MLS Week 25 action sees 14th place Toronto hosting ninth place Inter Miami at 7:30 pm EST Tuesday night.
While second-year Miami has rebounded from a sluggish start to the season and now looks to be edging towards their first-ever playoff appearance, Toronto FC can’t wait for this year to end as nothing has gone right.
🔎 Inter Miami’s recent run of form has made it clear: Phil Neville has righted the ship.
Here's a closer look at the 1-0 win vs. the Columbus Crew, including Neville's impact, Gonzalo Higuain's improved state, and more attacking troubles.#InterMiamiCFhttps://t.co/dKpEMnD2vB
— Franco Panizo (@FrancoPanizo) September 12, 2021
Inter Miami knocked off the defending champs in the Columbus Crew, 1-0 on Saturday. It was an early goal from Gonzalo Higuain in the 16′ minute which proved enough for the three points. Miami has now lost just once in their past ten matches and are 4-1-0 (WDL) in their past five.
Along with Nashville SC, that’s the best form (13 points) in the past five rounds. In the past ten rounds, only New England and Colorado have collected more points than Inter Miami.
The same can’t be said for Toronto who has collected the fewest points (six) in MLS over the past ten rounds—Columbus, Houston and Austin also share in that distinction.
Makin' moves in the East. ↕️ pic.twitter.com/cCDjdtc95r
— Major League Soccer (@MLS) September 13, 2021
If there was a time to try and salvage the season for Toronto, it was Saturday against FC Cincinnati. However, a second 2-0 loss to FCC this season ensued. TFC has now lost five straight and is winless in their past eight. They’ve kept one clean sheet all season so it’s likely Miami gets on the scoresheet.
At home on BMO Field, TFC could score. But they’ve scored multiple goals in a game only twice in 11 matches.
I could certainly see both teams scoring at -135. The score the last time these sides met in August was 3-1 to Miami. However, given the horrible form Toronto is in, a bet on Miami to simply not lose the match is my best bet.
Pick: Inter Miami – Double Chance (-140)
DC United vs Chicago Fire Prediction
Wednesday at 7:30 pm EST DC United will host the Chicago Fire in MLS Week 25.
DC United is coming off a 1-1 draw with New York Red Bulls on Saturday and sit sixth in the Eastern Conference. Chicago is coming off a 2-0 road defeat to Sporting Kansas City on Saturday and find themselves eight points out of the playoff picture in 12th.
" It was ugly, but I think it was a good point moving forward" – Hernan Losada #DCU #MMOS #MLS
— MyMindOnSports (@MyMindOnSports) September 12, 2021
This will be the fifth of six consecutive road matches for the Fire, a place where Chicago bets go to die usually. After failing to win for 19 straight games on the road, Chicago did actually pick up a win two rounds back, 1-0 over the Red Bulls.
Naturally, that was their first road win of the season and they were quickly back to their losing ways on the weekend.
DC’s matches have seen plenty of goals. At 14-9 to ‘Over’ 2.5 totals, only three teams have cashed at a higher rate for ‘Over’ bettors. Hernán Losada’s side will press, and they’ll score, and they’ll also be susceptible to conceding. Both teams have scored in each of their past seven matches and also in 11 of their past 13.

It will be the third meeting between the teams this season. On May 13, DC won 1-0 at home. On July 21 the teams split the points in a 2-2 draw. Chicago looked to be on their way to victory in July, leading 2-0 late on, before DC goals in the 82′ and 87′ minutes brought them level.
Chicago is porous on the road. DC’s games have been wide-open of late and despite their poor form, Chicago do have players capable of giving DC trouble in Robert Beric and Luka Stojanovic.
Pick: Both Teams to Score (-145)
Austin FC vs LAFC Prediction
It’s the third meeting between these teams this season when Austin FC hosts LAFC at 9:00 pm EST Wednesday night in MLS Week 25.
LAFC has already claimed 2-0 victories, both home and away in the previous two meetings and will be looking to make it a third win against the expansion side Wednesday. A win could push LAFC over the playoff line in the West as they currently sit tied with RSL on 30 points. RSL, on goal-differential, holds the tiebreaker.
LAFC and RSL actually just played on Sunday, the only teams to play on that day. The match was a spirited affair that saw LAFC claim a 3-2 win. The winning goal came from an embarrassing Toni Datkovic own goal in the 59′ minute. Cristian Arango scored a brace for LAFC earlier in the match. He’ll need to step up again as LAFC deals without the services of Carlos Vela (injured) and Diego Rossi (transferred). Brian Rodriguez was attending to personal matters in Uruguay on the weekend and could again be out.
He's just getting started. 🇨🇴📈@Chichoarango is your @MLS Player of the Week! #LAFC pic.twitter.com/x8nHhfTX2P
— LAFC (@LAFC) September 13, 2021
LAFC are now undefeated in three matches and is favored over the West’s bottom team, Austin FC.
Austin has one win in seven and have dropped three straight results, 5-3, 2-1 and 3-0 to Dallas, Vancouver and Houston respectively. After being one of the best ‘Under’ betting teams earlier in the season, Austin has been leaking goals of late. At least three goals have been scored in each of Austin’s last five matches.
As bad as a 3-0 defeat to a Houston team who was winless in 16 looks, Austin was in the game. They held 66-percent of the possession and hit the post right before the Dynamo went the other way with the ball to score their third goal.

Austin has the lowest xG at home this season in the West at 13.2. However, they’ve scored in each of their last four home matches and scored a combined ten goals in those games. Each of those games had at least three scored, with Austin conceding a combined 11 times.
LAFC is 14-9 to ‘Over’ 2.5 totals, propped up by 10/11 recent matches going ‘Over’. LAFC’s last four games have seen a combined 18 goals scored. Away from Banc of California Stadium, they’ve kept just two clean sheets in ten road matches. They’ve also allowed multiple goals in three of their past four on the road and in six of ten on the season.
Q2 Stadium should be rocking and if Austin can score their first goal against LAFC, the floodgates could soon open for a few goals in the match.
Pick: Both Teams to Score & over 2.5 Goals (-125)

Sports Editor
Ryan is SBD's resident soccer pro, though his repertoire is by no means limited to a single sport. His articles have been published by the Canadian Hockey League (CHL), Ontario Hockey League (OHL), and the Kitchener Rangers, and outlets like SportsXpress and Shredthespread.com