Premier League Matchday 5 Odds & Picks: Aston Villa vs Everton, West Ham vs Manchester United & More

By John Dillon in Soccer News
Published:

- Ten fixtures in England’s top-flight EPL starting on Friday thru until Sunday
- Brentford can surprise Wolves while Everton have begun well under new coach Rafa Benitez
- See all the odds, best bets and predictions for England Premier League Matchday 5 below
Manchester United is the early leader as England’s ultra-competitive Premier League heads into another frantic weekend of big games for Premier League Matchday 5.
Ole Gunnar Solskjaer’s United team leads on goal difference with Chelsea, Liverpool and Everton also on ten points from four games.
EPL Matchday 5 Odds
Matchup | Home | Draw | Away |
---|---|---|---|
Newcastle Utd vs Leeds Utd. | +200 | +260 | +135 |
Wolves vs Brentford | -115 | +230 | +390 |
Burnley vs Arsenal | +295 | +250 | +100 |
Man.City vs Southampton | _650 | +800 | +1500 |
Liverpool vs Crystal Palace | -476 | +600 | +1200 |
Norwich City vs Watford | +120 | +240 | +240 |
Aston Villa vs Everton | +140 | +240 | +200 |
Brighton & HA vs Leicester City | +170 | +220 | +175 |
West Ham Utd. vs Man.Utd | +350 | +300 | -130 |
Tottenham Hotspur vs Chelsea | +400 | +280 | -135 |
Odds as of September 17 at DraftKings
Wolves vs Brentford Prediction
Brentford suffered its first defeat as an EPL team last weekend while Wolves picked up its first win.
However, it is a surprise to see the oddsmakers at DraftKings making Wolves a wide favorite for the Saturday Premier League Matchday 5 early kick-off game – which offers value in getting behind Brentford.

There had been three straight defeats for Wolves before it finally came up with a 2-0 win at Watford last weekend.
Meanwhile, newly-promoted Brentford’s early campaign has understandably slipped following the euphoria of its opening-round 2-0 victory against Arsenal.
There have subsequently been two draws and a setback at home against Brighton & Hove Albion last Saturday.
𝙏𝙝𝙚 𝙨𝙩𝙤𝙧𝙞𝙚𝙨 𝙗𝙚𝙝𝙞𝙣𝙙 𝙩𝙝𝙚 𝙥𝙞𝙘𝙩𝙪𝙧𝙚𝙨
Thomas takes a trip down memory lane from his first 150 games in charge
Watch 𝘪𝘯 𝘧𝘶𝘭𝘭 on #TheWarmUp, Friday at 6pm
📺 Subscribe and get a reminder when we go live 👉 https://t.co/kwqe4F2pwQ #BrentfordFC pic.twitter.com/AsWDqJVM8A
— Brentford FC (@BrentfordFC) September 16, 2021
Still, there is a lot of attraction in the price of +390 for a Brentford win at Molineux.
Wolves, meanwhile, is priced somewhat puzzlingly at -115 with the draw at +260, which is also attractive. The kick-off is at 7:30 am ET.
Brentford’s energetic, high-pressing football has translated well to the EPL.
Certainly, Wolves have looked promising under new coach Bruno Lage’s counter-attacking system.
However, it was illusory as the team failed to score in its first three matches; going down by 1-0 against Leicester City, Tottenham and Manchester United.
Grafting for #WOLBRE.
💪⚽️ pic.twitter.com/inlGUxPYbo
— Wolves (@Wolves) September 16, 2021
Undoubtedly, those were tough opening fixtures.
But even then it required an own goal from Watford’s Francisco Sierralta to hand Wolves its first goal. Hwang Hee-Chan got the second.
Brentford’s energetic, high-pressing football has translated well to the EPL under coach Thomas Frank.

After the win against Arsenal, there was a 0-0 draw at Crystal Palace and a 1-1 draw at Aston Villa.
Additionally, it required a 90th-minute goal from Brighton’s Leandro Trossard to end Brentford’s unbeaten spell.
These teams last met in the Championship in January 2018 when Wolves was a 3-0 winner at home.
In conclusion this time, however, the odds favor taking a chance on the visitors.
Pick: Brentford win (+390)
Aston Villa vs Everton Prediction
New Everton boss Rafael Benitez has gone a long way towards winning over his new club’s fans after an impressive unbeaten start.
The 3-1 home win against Burnley last Monday put Everton in fourth place after three wins and one draw.

Certainly, it was a controversial move to appoint former Liverpool chief Benitez at Goodison Park.
Furthermore, it is surprising to see his side rated as a +200 outsider for the trip to Aston Villa on , which has won only once so far and is in 12th place.
— John McGinn (@jmcginn7) September 16, 2021
With kick-off at 12:30 pm ET on Saturday, Villa is rated at +140 with the draw at an attractive +240.
Obviously, it is a blow that Everton will be without injured leading scorer Dominic Calvert-Lewin, who has three goals.
New Villa striker Danny Ings has scored twice so far.
However, new signing Demarai Gray has also struck three times.
Villa was well beaten by 3-0 at Chelsea last weekend. Its only win was a 2-0 success against struggling Newcastle following a 3-2 defeat at Watford on the opening day.
https://youtu.be/cVDt-Wuv9Wg
There has also been a 1-1 draw at home against Brentford. And certainly, the team is re-adjusting after the departure of play-maker Jack Grealish for Manchester City.
New Villa striker Danny Ings has, however, scored twice so far.
But to sum up here, the odds favor taking a chance on Everton.
Pick: Everton to win (+200)
West Ham Utd vs Manchester Utd Prediction
Cristiano Ronaldo has scored three times in two games since his high-profile return to Manchester United.
Therefore, it is eye-catching to see the attractive price of +275 for him to be the first goalscorer in front of 60,000 at the London Stadium at 9:00 am ET on Sunday in Premier League Matchday 5.
West Ham, meanwhile, has made an excellent start with two wins and two draws placing it eighth.

However, despite the team’s impressive 2-0 win at Dinamo Zagreb in the Europa League on Thursday, the side may be tired after the trip.
Certainly, the Hammers’ looked weary in their first game back after the international break – a 0-0 draw at Southampton.
Cristiano Ronaldo’s mood looks ravenous and he loves to score on big occasions like this one.
United currently leads the table after three wins and a draw. But it suffered a shock 2-1 defeat at Young Boys of Berne in the UCL on Tuesday.
That, however, has handed the players two days extra recovery than the West Ham squad.
Quick flight over for a game in Europe, points in the suitcase, now it’s time to head back home with them! What a night ⚒ #COYI pic.twitter.com/lQCBv77qKo
— Michail Antonio (@Michailantonio) September 16, 2021
West Ham coach David Moyes may opt to keep it tight because leading scorer Michail Antonio is suspended.
But, to sum, up, Ronaldo’s mood looks ravenous and he loves to score on big occasions like this one.
Pick: Cristiano Ronaldo +275 (First Goalscorer)

Sports Writer
John Dillon is a leading member of the UK's sporting media, having spent three decades as a national newspaper soccer and sports writer, broadcaster and author. He has covered five World Cups, six European Championships and was Chief Sports Writer at the Daily Express for 14 years.