Opening College Football Week 7 Odds, Spreads and Early Predictions

By John Perrotto in College Football
Published:

- Week 7 of the college football seasons opens in earnest Thursday night with Baylor vs West Virginia
- Among the top games on Saturday are #3 Alabama vs #6 Tennessee and #10 Penn State vs #5 Michigan
- All the opening Week 7 college football odds can be found below with early predictions
Week 7 of the college football season begins in earnest Thursday night when Baylor visits West Virginia in a Big 12 game.
Baylor (3-2) has opened as a 3.5-point favorite after losing to Oklahoma State on Oct. 1. The same day, West Virginia (2-3) dropped a 20-13 decision to Texas.
There are a whopping six games involving ranked teams Saturday, including #3 Alabama vs #6 Tennessee, #10 Penn State vs #5 Michigan, #8 Oklahoma State vs #13 TCU, #7 USC vs #20 Utah, #15 North Carolina State vs #18 Syracuse and #16 Mississippi State vs #22 Kentucky
All the college football odds for Week 7 will be updated throughout the week
College Football Week 7 Opening Odds
Game Time (Eastern) | Team | Spread | Moneyline |
---|---|---|---|
Thursday, Oct. 13 | Baylor | -3.5 (-110) | OFF |
7 p.m. | West Virginia | +3.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Minnesota | -3.5 (-110) | OFF |
12 p.m. | Illinois | +3.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Auburn | +14 (-110) | OFF |
12 p.m. | Ole Miss | -14 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Iowa State | +14 (-110) | OFF |
12 p.m. | Texas | -14 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Miami | -8.5 (-110) | OFF |
12 p.m. | Virginia Tech | +8.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Penn State | +7.5 (-110) | OFF |
12 p.m. | Michigan | -7.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Kansas | +7.5 (-110) | OFF |
12 p.m. | Oklahoma | -7.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | California | -14 (-110) | OFF |
2 p.m. | Colorado | +14 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Arkansas | +2.5 (-110) | OFF |
3:30 p.m. | BYU | -2.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Vanderbilt | +37.5 (-110) | OFF |
3:30 p.m. | Georgia | -37.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Maryland | -10 (-110) | OFF |
3:30 p.m. | Indiana | +10 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Alabama | -7.5 (-110) | OFF |
3:30 p.m. | Tennessee | +7.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Oklahoma State | +2.5 (+110) | OFF |
3:30 p.m. | TCU | -2.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | NC State | +3 (-110) | OFF |
3:30 p.m. | Syracuse | -3 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | James Madison | -10 (-110) | OFF |
4 p.m. | Georgia Southern | +10 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Wisconsin | -5 (-110) | OFF |
4 p.m. | Michigan State | +5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Arizona | +15.5 (-110) | OFF |
5:30 p.m. | Washington | -15.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | LSU | +2.5 (-110) | OFF |
7 p.m. | Florida | -2.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Stanford | +16.5 (-110) | OFF |
7:30 p.m. | Notre Dame | -16.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Nebraska | +11 (-110) | OFF |
7:30 p.m. | Purdue | -11 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Clemson | -5.5 (-110) | OFF |
7:30 p.m. | Florida State | +5.5 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Mississippi State | -6 (-110) | OFF |
7:30 p.m. | Kentucky | +6 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | North Carolina | OFF | OFF |
8 p.m. | Duke | OFF | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | USC | +3 (-110) | OFF |
8 p.m. | Utah | -3 (-110) | OFF |
Game Time (Eastern) | Team | Spread | Moneyline |
Saturday, Oct. 15 | Washington State | +3.5 (-110) | OFF |
9 p.m. | Oregon State | -3.5 (-110) | OFF |
Odds as of October 9th DraftKings Sportsbook.
Georgia is the biggest favorite on the board at 37.5 points over Vanderbilt. The smallest line is 2.5 for BYU over Arkansas, TCU over Oklahoma State, and Florida over LSU.

Penn State vs Michigan Early Odds & Prediction
Two Big Ten unbeatens clash in Ann Arbor on Saturday when Michigan (6-0) hosts Penn State (5-0). The Wolverines have opened as 7.5-point favorites.
Michigan overcame a sluggish start Saturday to beat Indiana 31-10 on the road. The Wolverines did not go ahead for good until Cornelius Johnson caught a 29-yar touchdown pass from J.J. McCarthy midway through the third quarter.
CORNELIUS JOHNSON 😤@UMichFootball takes back the lead pic.twitter.com/KDxkOz1EhD
— FOX College Football (@CFBONFOX) October 8, 2022
McCarthy completed 28 of 36 passes for 304 yards and three touchdowns with one interception. Michigan is 6-0 for the second straight season, the first time the Wolverines have done that since 1976 and 1977.
Penn State was off this weekend after beating Northwestern 17-7 on Oct. 1.
The Nittany Lions are a surprising 5-0 but their perfect season will end in Big House as Michigan not only wins but covers.
Pick: Michigan -7.5 (-110)
Alabama vs Tennessee Early Odds & Prediction
In another matchup of teams with perfect records on Saturday, Alabama (6-0) will visit Tennessee (5-0) in the SEC. The opening odds show Alabama is a 7.5-point favorite.
Alabama slipped from the top spot of the AP poll Saturday, a day after struggling to beat Texas A&M 24-20 at home. The Crimson Tide needed a goal-line stand to win the game with Texas A&M throwing an incomplete pass at the 2-yard line as time expired.
One of the worst play calls possibly ever pic.twitter.com/BKgQ0ESQzb
— RedditCFB (@RedditCFB) October 9, 2022
Alabama quarterback Bryce Young sat out with a sore shoulder. Jalen Milroe made his first career start at QB, passing for 111 yards and three touchdowns and running for 183 yards but also throwing an interception and losing two fumbles.
Hendon Hooker passed for two touchdowns and Jabari Small ran for 127 yards and two scores to lead Tennessee to a 40-13 rout of LSU on the road.
This throw by Hendon Hooker was perfect. Followed by all the orange in the end zone going crazy! pic.twitter.com/ZAKHdfzObD
— CHANNEL TN (@CHANNEL_TN_) October 8, 2022
Hooker finished with 239 yards passing and both his touchdown throws went to Jalin Hyatt, covering 40 and 14 yards. Bru McCoy had seven receptions for 140 yards for the Volunteers.
With Young’s status up in the air, this is a hard game to pick, but look for Milroe to show improvement in his second start if he is needed.
Pick: Alabama -7.5 (-110)
Kansas vs Oklahoma Point Spread Is Outta Line
Oklahoma has opened as a 7.5-point favorite over Kansas and that is a real headscratcher.
Yes, Kansas (5-1) lost its first game of the season Saturday, falling 38-31 to TCU at home. And, yes, quarterback Jalon Daniels left the game in the second quarter and never returned.
However, Oklahoma (3-3) has been walloped 49-0 by Texas and 55-24 by TCU the last two weeks. No way the Sooners should be a TD-plus favorite.
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Sports Writer
John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.