Nationals vs Dodgers Prediction, Props & Odds for Saturday Night Baseball (June 21)

By Brady Trettenero in MLB Baseball
Published:

- The Washington Nationals visit the Los Angeles Dodgers on Saturday night at Dodger Stadium on June 21
- The Dodgers are massive home favorites with Dustin May taking the mound
- See the Nationals vs Dodgers prediction, player props, and odds for Saturday’s matchup
After the Dodgers took Friday’s series opener 6-5, the Washington Nationals (31-45) and Los Angeles Dodgers (47-30) square off in Game 2 at Dodger Stadium on Saturday, June 21st. First pitch is scheduled for 10:10 pm ET and the Dodgers are heavy home favorites in the Nationals vs Dodgers odds.
I’ve made my Nationals vs Dodgers prediction for Saturday night baseball, including a couple of prop picks, plus a breakdown of the odds.
Nationals vs Dodgers Prediction for Saturday Night
- Over 9.5 total runs (-114 at DraftKings)

Everything points to runs on Saturday night. The wind’s blowing out at Dodger Stadium, creating ideal hitting conditions. Both starting pitchers bring concerning trends that should have bettors running to the over.
These teams have combined for 46 runs in their four meetings this season. That’s 11.5 per game. Each contest has sailed over the total, and there’s no reason to expect that trend to stop now. The Dodgers lead MLB with a 45-31-1 OVER record, while the Nationals have gone over in six of their last nine games.
Washington vs LA Starting Pitching Matchup
Jake Irvin takes the hill for Washington. The 28-year-old right-hander owns a 5-3 record despite concerning underlying numbers. His 5.24 xERA sits over a full run higher than his actual ERA, suggesting regression is coming. He’s allowed lefties to slash .265/.319/.500 this season with a 5.33 FIP. Bad news against Freddie Freeman and Shohei Ohtani.
Irvin’s road splits are equally troubling. He carries a 4.97 ERA away from Nationals Park, and now faces a Dodgers lineup that leads MLB with a .917 OPS with runners in scoring position.
Dustin May counters for the Dodgers with a 4.46 ERA that doesn’t tell the whole story. He’s allowed multiple runs in nine of his last 10 starts, often getting extended beyond optimal pitch counts due to the Dodgers’ taxed bullpen. The injuries have forced Dave Roberts to leave May in games longer than ideal, leading to crooked numbers in the middle innings.
The bullpen situation screams over. Washington’s relief corps ranks dead last in MLB with a 5.61 FIP in June. Meanwhile, the Dodgers’ pen has been stretched thin covering for injured starters. Even their reliable arms have shown cracks under the increased workload.
Factor in the weather (wind blowing out), and this shapes up as a hitter’s paradise. At -114, the over 9.5 offers solid value. Don’t overthink this one.
Dodgers vs Nationals Player Props (June 21)
Shohei Ohtani (.292 BA, .617 SLG, 25 HR, 44 RBI) has the shortest home run odds at +150. The superstar has already gone 4-for-8 with a 1.181 OPS against Irvin in his career.
James Wood (.279 BA, .554 SLG, 20 HR, 56 RBI) leads the Nationals’ power surge at +400 to leave the yard.

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MLB player props from DraftKings on June 21.
MLB Player Prop Picks for Saturday
- Freddie Freeman over 1.5 total bases (-115)
- Shohei Ohtani over 0.5 RBI (-120)
Freeman’s matchup against Irvin looks particularly juicy. After getting Friday off to rest his ankle and quad, he’ll return to face a pitcher who’s allowed lefties to slug .500. Freeman’s destroying righties this year with a 177 wRC+ and typically performs well against both curves and changeups, which Irvin mixes in against lefties. His 1.5 total bases at -115 feels like stealing.
Ohtani’s RBI prop also catches my eye. The NL MVP favorite has already gone 4-for-8 with a 1.181 OPS against Irvin in his career. That’s not a small sample. Ohtani clearly sees the ball well against this pitcher. With the Dodgers’ elite lineup setting the table, getting -120 odds on the superstar driving in a run seems like terrific value.
Washington Nationals vs Los Angeles Dodgers Odds
The Dodgers come in as massive -271 favorites at DraftKings, which speaks to their dominance at home and the pitching matchup. That price implies a 73% win probability for Los Angeles. The Nationals check in at +215, giving underdog bettors a decent return if Washington can pull the upset.
The run total of 9.5 leans slightly toward the over at -114. With both pitchers showing vulnerability and the wind expected to blow out, DraftKings is essentially telling us they expect fireworks.
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Odds as of June 21. Check out SBD’s list of the best MLB betting apps.
Friday’s series opener stayed close throughout before the Dodgers pulled away late for a 6-5 victory. All four previous meetings between these teams this season have sailed over the total, averaging 11.5 combined runs per game.
Saturday’s MLB public betting splits heavily favor the home team. Los Angeles has attracted 89% of the moneyline handle, while the public is also backing the over (93%) with the wind conditions and offensive firepower on display.

Lead NHL & NCAAF Editor
Brady is the lead NHL and College Football editor at Sports Betting Dime, where he specializes in betting odds and data-driven analysis. Brady has over 10 years experience working in sports media, with work published by outlets such as ESPN, CBS Sports, Yahoo! Sports and Fox Sports.