Brewers vs Cubs Predictions, Picks, Player Props & Pitchers (Game 3)

• The Brewers can sweep the Chicago Cubs out of the NLDS Wednesday, October 8th
• Quinn Priester vs Jameson Taillon is the pitching matchup in a series that has seen tons of runs scored early
• See the Game 3 Brewers vs Cubs picks, predictions, and player props to bet, plus the latest odds

Following 9-3 and 7-3 wins at home, the Milwaukee Brewers (99-65, 45-36 road) can eliminate the Chicago Cubs (94-73, 52-32 home) in Game 3 of their best-of-five NLDS Wednesday night to reach their first NLCS since 2018. First pitch is scheduled for 4:08 pm CT/5:08 pm ET at Wrigley Field in Chicago.

Milwaukee turns to right-hander Quinn Priester (13-3, 3.32 ERA, 1.24 WHIP) to close out their NL Central rivals. Chicago counters with righty Jameson Taillon (3.68 ERA, 1.06 WHIP) who pitched four scoreless innings, allowing two hits while striking out four in the Cubs Wild Card series clincher against the Padres.

Below, see my Brewers vs Cubs picks for Game 3, plus the main player props, pitcher stats, and the updated odds.

Milwaukee Brewers vs Chicago Cubs Pick for Game 3

• Over 6.5 runs scored (-121), 1st inning over 0.5 runs scored (+120)

This series has seen runs scored early and often – in the first two duels, they’ve combined for 13 runs scored in the opening frame, setting an MLB postseason record. With that said, the value at +120 for over 0.5 runs scored in the first inning is too good to pass up.

Chicago has a 51.4% chance of emerging victorious in the Brewers vs Cubs odds. The Cubbies have won eight of their last twelve games at Wrigley Field, while the Brewers have lost seven of their last nine on the road. In all but three of the 15 matchups between these two rivals in 2025, at least seven total runs have been scored, so I love the over run total in this one.

Brewers vs Cubs Game 3 Player Props

MLB player props as of October 7 at DraftKings

Brewers pitcher Quinn Priester has his strikeout line set at 3.5, and his total outs at 12.5, compared to 2.5 and 10.5 for his counterpart Jameson Taillon.

For Milwaukee hitters, Jackson Chourio has a total bases line of 1.5 (+121) and he’s 7-13 with a home run and four RBIs in 13 plate appearances against Taillon in his career. For Chicago, Nico Hoerner is +138 to get over 1.5 bases – he has four hits in eight at-bats off Priester in 2025, to go along with a home run and two RBI.

Best Brewers vs Cubs Player Prop to Bet: James Taillon Over 2.5 Strikeouts (-115)

Game 3 Pitching Matchup

The Brewers are sending out Quinn Priester, who has made three starts against the Cubs this season, going 4.1 innings in the first and third outings, and 5.2 in the middle duel. He’s surrendered a combined ten earned runs and has a 6.20 career ERA versus the Cubs in four starts. Chicago counters with Jameson Taillon, who has a 3.33 career ERA versus Milwaukee, going six innings in two of three battles against the Brew Crew this year. He has at least three strikeouts in 18 of 21 games against Milwaukee in his career, and eight of his last nine outings on the campaign.

Quinn Priester vs Jameson Taillon 2025 Stats

MIL Brewers vs CHI Cubs Game 3 Odds

As of 6:15pm CT Tuesday night, the Cubs were -123 or to keep this series going, while their adversaries were +102 to book their ticket in the NLCS. The game total has held steady at 6.5 with the over slightly juiced at most books.

The price bettors can currently find on the Milwaukee runline (-1.5) is +180. If you want to bet Chicago +1.5, you’ll have to stomach -223 odds at DraftKings.