Odds to Win Mid-West Region Favor Illinois

By Chris Amberley in College Basketball
Published:

- Top seed Illinois has the shortest Final Four odds of any team in the Mid-West Region
- The Fighting Illini have six wins over top-10 teams this season, and the most Quadrant 1 victories in all of college basketball
- See below for the Final Four odds of every team in the Mid-West Region, plus analysis and a pick
The NCAA Tournament field is set, which means it’s time to analyze the pretenders and contenders for each region. Our focus is squarely on the Mid-West Region, where top seed Illinois is looking to get back to the Final Four for the sixth time in school history, and for the first time since 2005.
The Fighting Illini will face some stiff competition along the way, with red-hot programs like Oklahoma State, Houston and San Diego State all on their side of the draw, but the Big Ten champs have excelled in tough matchups all season, and there’s little reason to believe that will change over the next few weeks.
2021 Mid-West Region Final Four Odds
Team (Seed) | Odds |
---|---|
Illinois Fighting Illini (1) | +100 |
Oklahoma State Cowboys (4) | +300 |
Houston Cougars (2) | +350 |
West Virginia Mountaineers (3) | +400 |
Tennessee Volunteers (5) | +900 |
San Diego State Aztecs (6) | +900 |
Loyola-Chicago Ramblers (8) | +900 |
Georgia Tech Yellow Jackets (9) | +1500 |
Clemson Tigers (7) | +2000 |
Syracuse Orange (11) | +2000 |
Oregon State Beavers (12) | +2000 |
Cleveland State Vikings (15) | +3000 |
Drexel Dragons (16) | +3000 |
Liberty Flames (13) | +5000 |
Morehead State Eagles (14) | +5000 |
Rutgers Scarlet Knights (10) | OFF |
Odds taken March 14th at DraftKings.
Not surprisingly, Illinois has the shortest Final Final Four odds in the Mid-West Region, and while there are a handful of teams who could potentially emerge from this side of the draw, there’s also four we can cross-off right away.
The Cross-Offs
No disrespect to Drexel, Cleveland State, Morehead State or Liberty, but your team is not going to be the last one standing in the Mid-West.
These four teams combined don’t have a single victory over a team ranked inside the top-73 this season, and only the Flames have made a March Madness appearance since 2011.
THE BRACKET!#MarchMadness pic.twitter.com/6tRUVIXS4X
— NCAA March Madness (@MarchMadnessMBB) March 14, 2021
They each rank 97th or worse in KenPom’s overall efficiency ratings and are all at least a 9.5-point underdog in their First Round matchup on Friday.
The Sleeper
One program likely to fly under the radar is sixth seed San Diego State. The Aztecs enter the tournament having won 14 straight, and rate 20th in KenPom’s metrics, and 18th in the NCAA NET rankings.
Happy but not content.
✈️ up to Indy. pic.twitter.com/LfuasDZW7v
— San Diego State Men's Basketball (@Aztec_MBB) March 14, 2021
10 of their 14 wins during their winning streak have been by double-digits, and only seven teams in the nation allow fewer points per game. All five of their top players are upperclassmen, led by Jordan Schakel and Matt Mitchell, and they shot 40% from beyond the arc in Mountain West play. +900 is a great price for a strong defensive team, that can shoot the lights out and is loaded with veterans.
The Contenders
The Houston Cougars head to Indiana winners of 17 of their past 19 games, including seven straight. They cruised to a 37-point win in the AAC Championship game, and are a statistical darling. They rank eighth in offensive efficiency, 16th in defensive efficiency, and are the fourth best rebounding team in the country.
Cutting down nets never gets old#ForTheCity x #GoCoogs pic.twitter.com/tKR2OMHBL2
— Houston Men's Hoops 🏀 🐾 (@UHCougarMBK) March 15, 2021
There’s a problem though. Their best wins are over SMU, Memphis (twice), Texas Tech and Wichita State. Only the Red Raiders and Shockers qualified for March Madness, and it’s hard to justify laying +350 on a program without a better resume.
The same can’t be said for No. 4 seed Oklahoma State. Over the past few weeks, this team has six wins over top-25 competition, most recently handing Baylor just its second loss of the season in the Big 12 semifinal.
https://twitter.com/SportsCenter/status/1370550344997085187
The Cowboys are led by Cade Cunningham, the projected number one overall pick in the NBA Draft, and they have the second most Quadrant 1 wins in the nation, behind only Illinois.
The Best Bet
Speaking of the Fighting Illini, it’s hard to bet against them at the moment. They’ve won seven in a row, 14 of 15, and are fresh off winning the toughest conference in all of college hoops. They have six wins over top-10 teams, and as mentioned the most Quadrant 1 victories.
"Illinois' Fighting Illini are the No. 1 seed! One of the powerhouses down the stretch." #Illini | #EveryDayGuys pic.twitter.com/fMa3O1nOjX
— Illinois Men's Basketball (@IlliniMBB) March 15, 2021
They have size, experience, depth and one of the best players in the nation in Ayo Dosunmu. The Wooden Award contender averaged 21 points per game and led Illinois past Iowa and Ohio State (a pair of 2-seeds) en route to a conference title. Another thing working in their favor is their ability to overcome adversity. Over a three game stretch two weeks ago, they beat Nebraska, #23 Wisconsin and #2 Michigan (by 23), all while Dosunmu was out.
If you’re looking for a longshot bet the Aztecs, otherwise roll with the Fighting Illini.
Pick: Illinois Fighting Illini (+100)

Sports Writer
As SBD's resident Swiss Army Knife, Chris covers virtually every sport including NFL, PGA, NBA, MLB, NCAAB, NCAAF and the Olympics. A true grinder, he'd rather pick off small edges in the player props market than swing for the fences with a 5-leg parlay.