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Cornhuskers Open as Razor-Thin Favorite in Vanderbilt vs Nebraska Odds

Sascha Paruk

By Sascha Paruk in College Basketball

Published:


Vanderbilt Commodores forward Tyler Nickel gestures after hitting a three
Vanderbilt Commodores forward Tyler Nickel (5) celebrates after making a 3-pointer during a first-round game in the NCAA men's basketball tournament between McNeese and Vanderbilt at Paycom Center in Oklahoma City, Thursday, March 19, 2026.
  • #5 Vanderbilt will meet #4 Nebraska in the NCAA Tournament second round
  • The teams are separated by just one spot at KenPom
  • See the opening Vanderbilt vs Nebraska odds for March 21st, 2026

The SEC’s biggest surprise will meet the Big Ten’s biggest surprise on Saturday with a spot in the Sweet 16 on the line. The #5 Vanderbilt Commodores (27-8, 18-17 ATS) will #4 Nebraska Cornhuskers (27-6, 18-14-1 ATS) will square off at Paycom Center in Oklahoma City on March 21st (start time TBD).

The opening odds for Vandy/Nebraska could scarcely be closer.

Opening Vanderbilt vs Nebraska Odds & Lines

Bet TypeVanderbiltNebraska
Spread+1.5 (-118)-1.5 (-102)
Moneyline-110-110
TotalO 146.5 (-110)146.5 (-110)

The spread opened with Nebraska as a 1.5-point neutral-court favorite but the Huskers were priced at -102 to cover.Vandy +1.5 opened at -118. On the moneyline, both teams were priced at -110 with the game total at 146.5 (-110 each way).

Within minutes of the line opening, Vandy had shortened to -125 on the moneyline and -2.5 (-110) against the spread. The total had increased a full point to 147.5.

Odds in table as of 5:29 pm ET at DraftKings. Find the best betting app for March Madness.

Vanderbilt beat #12 McNeese (78-68) on Thursday, getting a game-high 26 points from Tyler Tanner. Nebraska routed #13 Troy (76-47) with Pryce Sandfort’s 23 points leading the charge.

According to Sportradar data, these two schools haven’t played since 2010.

Vanderbilt is well ahead of Nebraska in the March Madness championship odds (+7000 vs +12500).

Vanderbilt vs Nebraska Season Stats

VanderbiltStatisticNebraska
26-8Overall Record27-6
5-1Neutral Record4-1
12thKenPom Rank13th
13thNET Rank14th
.591 (#24 nationally)SOS.559 (#81 nationally)
35.5%3P%35.3%
9-7Quad 1 Record7-6
6-1Quad 2 Record4-0

The teams are separated by just one spot in both the KenPom rankings and NET Rankings; the Dores sit on spot higher in both. Vandy is two spots higher at Haslametrics (16th vs 18th) and eight spots higher at BartTorvik.com (10th vs 18th).

Bookmark SBD’s college basketball odds page to see current lines for all NCAA Tournament games.

Sascha Paruk
Sascha Paruk

Managing Editor

Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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