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Duke vs TCU Opening Odds for Second Round
By Sascha Paruk in College Basketball
Published:
- #1 Duke survived a huge test from Siena and will face #9 TCU in the second round
- The top-seeded Blue Devils have opened as big favorites against the Horned Frong
- See the opening Duke vs TCU odds for the 2026 NCAA Tournament round of 32
The #1 Duke Blue Devils (33-2, 19-16 ATS) overcame an 11-point halftime deficit and survived a huge scare from #16 Siena, setting up a second-round clash with the #9 TCU Horned Frogs (23-11, 19-15 ATS) on Saturday, March 21st. Tip-off time is TBD at Bon Secours Wellness Arena in Greenville, SC.
Despite a lackluster showing on Thursday, Duke still sits first at KenPom and still leads the March Madness championship odds. Jon Scheyer’s group has also opened as a heavy favorite to reach the Sweet 16.
Opening Duke vs TCU Odds
Duke has opened as 12.5-point ATS favorites and -850 on the moneyline. The Frogs are +575 to advance to the Sweet 16, something they haven’t done since 1968.
The game total has opened at 137.5 with -110 odds both ways.
Odds as of March 19th at DraftKings. Learn how to bet on sports in Texas.
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Duke’s comeback was spurred by another big night from Cameron Boozer (22 points, 13 rebounds, 3 assists) along with suffocating second-half defense. Siena scored just 22 points in the final 20 minutes after scoring 43 in the first.
TCU was almost the victim of a massive comeback attempt by Ohio State in their tournament opener. The Frogs led 39-24 at the break but found themselves in a seesaw affair down the stretch, hanging on for a 66-64 win. David Punch has a dominant 16-point, 13-rebound double-double with three blocks and two dime.
The Duke vs TCU team stats exemplify the Blue Devils’ edge.
Duke vs TCU Team Stats
Bookmark SBD’s college basketball odds page to see up-to-the-minute lines for every game of the 2026 NCAA Tournament.
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Sascha Paruk
Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.
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