Final Iowa State vs Kansas State Prediction, Odds & Head-to-Head History

• Iowa State is a 3-point underdog against Kansas State in Saturday’s Dublin showdown
• The Cyclones have covered five straight meetings with the Wildcats, including 4-1 straight up
• Check out our Iowa State vs Kansas State prediction and updated College Football Week 0 odds

College football kicks off in style this Saturday as Iowa State and Kansas State clash in Dublin for the Aer Lingus Classic. The game carries massive Big 12 implications with both teams expected to compete for the conference title.

Online sportsbooks have installed the Wildcats as slight favorites, but the latest College Football odds suggest this one could go either way.

Here is our final Iowa State vs Kansas State prediction for Saturday’s Week 0 Dublin showdown, along with an odds update and H2H analysis.

Final Iowa State vs Kansas State Prediction

• Iowa State +3 (-105 at Bet365)

This line feels like a trap. Kansas State may have finished 9-4 last season, but they went just 4-9 against the spread. That’s brutal for bettors who backed them consistently. Meanwhile, Iowa State went 8-6 ATS and knows exactly how to keep games close.

The Cyclones are returning to what works: a physical, ground-heavy attack. Carson Hansen rushed for 752 yards and 13 touchdowns last year. He’s ready to carry the load behind an offensive line returning 106 combined starts. That’s the kind of experience that travels well to Dublin.

Kansas State has major question marks in the secondary. They’re breaking in two new corners and a safety against Rocco Becht, who threw for 3,505 yards and 25 touchdowns last season. Becht is clutch in big moments. He led four game-winning drives last year against quality opponents.

The Wildcats also have offensive line concerns. They’re missing projected starter George Fitzpatrick at left tackle and five-star freshman Linkon Cure at tight end. Avery Johnson threw 10 interceptions last year when pressured. Iowa State’s defense will attack those weak spots early and often.

What really stands out is Kansas State’s red zone inefficiency. In their four losses last year, they had 13 red zone trips but scored just five touchdowns. That’s not going to cut it against a disciplined Iowa State defense that ranked top-30 nationally in yards per play allowed.

The neutral site in Dublin means neither team has a home advantage. Both teams are dealing with travel and jet lag. In these scenarios, you want the team getting points that can control the clock and keep it close. That’s exactly what the Cyclones do best.

Matt Campbell is now 5-0 ATS in his last five meetings with Chris Klieman. He’s 4-1 straight up in those games too. When you see a trend this strong, you don’t ignore it. Take the points and trust what’s been working.

Iowa State vs Kansas State Odds

Kansas State opened as 3.5-point favorites, but early Iowa State money pushed this down to -3. The line has been hovering at this key number for days now. Sharp money appears split, with Kansas State drawing slightly more tickets while Iowa State is seeing bigger bets come in.

The total opened at 50.5 and has crept up to 51. About 60% of the money is actually on the under per College Football public betting trends, which could push this back down before kickoff.

Saturday’s Week 0 clash kicks off at noon ET from Aviva Stadium in Dublin, Ireland. ESPN has the broadcast for this neutral-site showdown. Kansas bettors can now get in on the action as Bet365 recently launched in the Sunflower State.

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Odds as of August 22 at Bet365. Check out the best sports betting app before betting on Week 0.

Iowa State vs Kansas State Head-to-Head History

The Cyclones have absolutely dominated this series recently. Check out the last five meetings:

That’s 5-0 ATS for Iowa State over the last five years. Even when Kansas State won in 2022, they couldn’t cover as favorites. The Cyclones just have K-State’s number.

Last year’s meeting saw Iowa State win 29-21 as slight favorites. Avery Johnson managed just 64 rushing yards against the Cyclones defense. Hansen and the ISU ground game controlled the tempo and clock.

The series has gone under the total in three of the last five meetings. But with both teams featuring experienced quarterbacks and question marks on defense, Saturday’s game could see more points.

Campbell has figured out how to beat Kansas State. The Cyclones use heavy personnel packages to control the line of scrimmage and keep Johnson’s offense off the field. They force the Wildcats into uncomfortable third-down situations where mistakes happen.

When you combine the head-to-head dominance with Iowa State’s ability to cover as underdogs (5-3 ATS 2023 + 2024), taking the points is the best bet. The Cyclones have proven they belong in these big games.

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