Tennessee vs South Carolina Odds, Spread and Prediction

By Nick Holz in College Football
Published:

- #5 Tennessee takes on South Carolina in an SEC East matchup on Saturday, November 19th
- Tennessee is an astounding 8-2 against the spread this season
- Check out all the odds and our best bets for Tennessee vs South Carolina below
College football week 12 action gets underway on Saturday as SEC East rivals Tennessee and South Carolina clash.
Despite a recent setback against Georgia, Tennessee still has a lot to play for.
Meanwhile, South Carolina has suffered through yet another disappointing season. The Gamecocks sit at 6-4 and will be hoping to improve their standing for Bowl season.
Let’s explore all the Tennessee vs South Carolina odds as we offer you our best bets for Saturday’s SEC matchup.
Tennessee vs South Carolina Odds
Team | Spread | Moneyline | Total |
---|---|---|---|
Tennessee | -21.5 | -2000 | Over 66.5 (-110) |
South Carolina | +21.5 | +1000 | Under 66.5 (-110) |
Odds as of November 17th at BetMGM.
Tennessee enters this one as heavy 21.5-point favorites. Predictably, bettors are all over the Volunteers to cover the spread in this one, as 86% of bets placed against the spread favor Tennessee. The total for Saturday’s Tennessee vs South Carolina matchup sits at 66.5 points.

Tennessee vs South Carolina kicks off from Williams-Brice Stadium at 7pm ET on Saturday, with the action being televised by ESPN. The Weather forecast in Columbia calls for 53-degree temperatures with potential showers.
Tennessee Betting Trends
Following a disheartening loss to Georgia, Hendon Hooker and the Tennessee Volunteers decimated the Missouri Tigers last week. The Volunteers put up 21 points in each of the second and third quarters en route to a 66-24 victory.
As Josh Heupel’s pupils look to build momentum on last week’s rout, Hooker will aim to cement his Heisman trophy resume on Saturday. After all, a stupendous stretch run could see the Vols pivot surpass Ohio State quarterback CJ Stroud as the favorite for the award. Hooker has put up video game-like numbers in his second year as Tennessee’s starter. Hooker has racked up 2,888 passing yards and 24 touchdowns while completing an incredible 71% of his passes and averaging an eye-popping 10.1 yards per attempt. The Greensboro, North Carolina native has added an additional 400 rushing yards and 5 scores on the ground.
A deep stable of playmakers at every skill position makes this Tennessee offense incredibly fun to watch.
Hendon Hooker today vs. Missouri:
25/36
355 YDS
4 TOT TDSTennessee won 66-24 📈 pic.twitter.com/5bEq0cpbZM
— Bleacher Report (@BleacherReport) November 12, 2022
Numerous betting trends favor the Volunteers in this one. Tennessee is 5-1 against the spread in their last six overall, while the Volunteers are 8-2-1 ATS in their last 11 meetings in South Carolina.
South Carolina Betting Trends
Head coach Shane Beamer and South Carolina will look to bounce back after a 38-6 blowout loss to Florida last week.
Former Oklahoma Sooner Spencer Rattler has been a disappointment thus far in his Gamecocks’ tenure. Granted, he hasn’t been offered much help. Rattler has tossed for just 1,982 yards and 8 touchdowns with 9 interceptions.
South Carolina punter Kai Kroeger: 1/1, 48 yards, TD
South Carolina QB Spencer Rattler: 5/9, 40 yards, 0 TDpic.twitter.com/rtL90IzqXF
— Yahoo Sports College Football (@YahooSportsCFB) November 12, 2022
Meanwhile, the Gamecocks’ defense has struggled mightily the past few weeks. The Gamecocks are surrendering nearly 200 rushing yards per game, and a horrific 4.8 yards per attempt on the season. That won’t bode well against a talented Vols offensive line.
Bettors should be wary of backing this South Carolina team, as the Gamecocks are just 6-15 against the spread in their last 21 conference games.
Tennessee vs South Carolina Prediction
Without a conference or division title, Tennessee will have to dress to impress on Saturday in South Carolina. While the Gamecocks are unranked, another statement road win against a bowl-bound SEC program should strengthen the Vols’ claim to a top-four spot. Josh Heupel’s men can’t control the insanity that is bound to hit other college football fields around the country over the next few weeks. However, the Volunteers can put the boot to the South Carolina Gamecocks on Saturday night.
Expect Tennessee to come out guns blazing and lay the hammer to a vulnerable South Carolina defense. That being said, with the huge spread involving three scores and the hook, the value lies in betting the over.
Pick: Tennesse vs South Carolina OVER 66.5 (-110)
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Sports Content Writer
A sports betting aficionado and graduate of Toronto Film School, Nick covers the NFL, NBA, Soccer, and MMA for SBD. He is also an avid NBA podcaster, and sports betting TikToker. Nick's work has been featured on Bleacher Report.