Padres vs Giants Odds, Lines, and Picks (Sep. 13)

By Chris Amberley in MLB Baseball
Published:

- The San Francisco Giants are -110 favorites over the San Diego Padres on Monday (September 13th, 9:45 pm ET)
- San Diego will give the ball to Yu Darvish (8-9, 3.95 ERA), while it will be a bullpen game for San Francisco
- Read below for odds, analysis and a betting prediction
Baseball’s best team keeps getting better. The San Francisco Giants strolled into Wrigley Field this past weekend and promptly swept the Chicago Cubs, running their win streak to seven games in the process.
The Giants will look to make it eight in a row on Monday (September 13th), as they host the rival San Diego Padres.
Padres vs Giants Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
San Diego Padres | -106 | -1.5 (+158) | O 8.5 (-104) |
San Francisco Giants | -110 | +1.5 (-192) | U 8.5 (-118) |
Odds as of September 12th at DraftKings.
San Francisco opened as -110 moneyline favorites, in a game that features a total of 8.5. First pitch is scheduled for 9:45 pm ET at Oracle Park, with clouds and 66 degree temperatures in the forecast.
Probable Pitchers
Thanks to an elbow injury to Johnny Cueto, and a positive Coronavirus test for Alex Wood, the Giants are left without a starter to trot out on Monday. As a result, the team will throw a bullpen game with right-hander Dominic Leone expected to be up first.
The right-hander has filled this role twice this season, with both “starts” coming in the last week. Leone threw two shutout innings on Friday against the Cubs, and a single scoreless inning last Sunday against the Dodgers.
Six up, six down for Dominic Leone. First time the #SFGiants have stretched him beyond one inning since June 4.
He's got a 1.48 ERA this year.
— Kerry Crowley (@KO_Crowley) September 10, 2021
Leone hasn’t allowed an earned run over his past five outings, and sports a tidy 1.48 ERA and 1.05 WHIP this season. The Giants bullpen as a unit leads MLB in ERA, and ranks top eight in WAR and strand rate.
San Diego’s bats have been ice cold recently, and are fresh off being shutout twice in the past three days. They were outscored 14-4 by the LA Dodgers over the weekend, and have been blanked three times in their past five contests.
Darvish vs Giants Bullpen
8-9 | Record | 38-20 |
3.95 | ERA | 3.06 |
1.05 | WHIP | 1.09 |
.222 | OBA | .209 |
5.3 | SO/W Ratio | 2.9 |
The Padres meanwhile, will counter with Yu Darvish, as they look to snap a three-game losing streak. The 35-year-old is on pace for his worst full season as a starter, despite posting respectable advanced metrics. His 3.66 xFIP and 10.73 K/9 rate are in line with his career averages, while his hard hit allowed rate is actually lower than his average over nine seasons.
He endured a brutal stretch between July and the first week of September, but rebounded nicely is his last outing. Facing the LA Angels on Wednesday, he surrendered just three hits and one run, while striking out seven.
Yu Darvish, Nasty 80mph Slider…and fist pump from Caratini. pic.twitter.com/SfPxy8S2cF
— Rob Friedman (@PitchingNinja) September 9, 2021
Prior to that start, he yielded at least four runs in three straight outings, and in seven of his past nine appearances. He’s made two starts against San Fran in 2021, and both were outstanding efforts. He’s 1-0 against MLB’s top club, with a 1.46 ERA and a 19-4 strikeout-to-walk rate over 12.1 innings.
Batting Average vs Starting Pitchers
Padres Batters | Batting Average vs Giants | Giants Batters | Batting Average vs Darvish |
---|---|---|---|
Austin Nola | .000 | Brandon Belt | .111 |
Eric Hosmer | .324 | Kris Bryant | .000 |
Adam Frazier | .323 | Brandon Crawford | .300 |
Manny Machado | .200 | Evan Longoria | .154 |
Wil Meyers | .241 | Buster Posey | .273 |
Trent Grisham | .333 | Wilmer Flores | .000 |
Fernando Tatis Jr. | .200 | Mike Yastrzemski | .333 |
Tommy Pham | .238 | Tommy La Stella | .200 |
The Giants lineup has been ret-hot lately, scoring at least six runs in each of the seven games during their winning streak. They’ve crossed the plate 12 or more times on three occasions during that stretch, and outscored the Cubs 27-10 over the weekend.
Padres vs Giants Pick
These two teams will meet 10 times in the next month starting with a four-game set this week. San Fran owns a 5-4 series advantage in 2021, with seven of the nine contests producing eight runs or less.

Given the strength of the Giants bullpen, combined with the Padres offensive struggles and Darvish toeing the rubber, it makes sense to target another low scoring contest.
Pick: Under 8.5 (-118)Â

Sports Writer
As SBD's resident Swiss Army Knife, Chris covers virtually every sport including NFL, PGA, NBA, MLB, NCAAB, NCAAF and the Olympics. A true grinder, he'd rather pick off small edges in the player props market than swing for the fences with a 5-leg parlay.