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White Sox vs Yankees Picks and Odds (May 21)

Robert Duff

by Robert Duff in MLB Baseball

May 20, 2022 · 8:15 PM PDT

Chicago White Sox vs New York Yankees
May 14, 2022; Chicago, Illinois, USA; Chicago White Sox shortstop Tim Anderson (7) throws to first base after forcing New York Yankees third baseman Josh Donaldson (28) out at second during the sixth inning at Guaranteed Rate Field. Mandatory Credit: Matt Marton-USA TODAY Sports
  • The New York Yankees are -220 home favorites over the Chicago White Sox in an American League afternoon game slated for Saturday, May 21
  • Friday’s series opener was postponed due to rain. It will be made up as part of a doubleheader on Sunday, May 22
  • All of the White Sox vs Yankees odds, picks, predictions and best bets are analyzed in the story below

The New York Yankees (28-10, 14-4 home) are rolling, while the Chicago White Sox (19-19, 10-9 road) continue to find themselves scuffling as the two teams move into the final third of the month of May.

New York is 21-4 over the past 25 games. Chicago continues to tread water. The ChiSox are 6-6 through their past 12 games.

It’s the Yankees that oddsmakers are expecting to continue winning when these two clubs take the diamond on Saturday. The MLB betting lines are showing that New York is a solid -220 home favorite. The Yanks are 10-1 straight up in their last 11 home games.

White Sox vs Yankees Odds

Team Moneyline Runline Total
Chicago White Sox +190 OFF O 9 (-115)
New York Yankees -220 OFF U 9 (-105)

Odds as of May 20th at Caesars Sportsbook.

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The first pitch is slated to be thrown at 1:05pm ET on Saturday, May 21 at Yankee Stadium. While Friday’s series opener was rained out, Saturday’s forecast is calling for clear skies, 11 mph wind and a temperature of 91 degrees.

While a solid straight up  play, the Yankees are just 20-18 against the runline and 9-9 at home. The White Sox are 18-20 ATR and 11-8 ATR away from home.

Across the leading sportsbooks, New York is the -220 odds-on favorite to win the division in the AL East odds. Despite their struggles, the White Sox remain the -170 odds-on chalk to emerge with the AL Central flag.

Southpaw Showdown In The Bronx

In this battle of lefties, it’s the White Sox who are sending a former Cy Young Award winner to the hill. But it’s the Yankees who are favored.

Dallas Keuchel won the AL Cy Young Award with the Houston Astros in 2015. However, this year, he’s looking nothing like that pitcher. Keuchel’s ERA (5.54) is a career high and his strikeouts/walks ratio (1.07) is a career low. His 1.96 WHIP is Keuchel’s worst since his 2012 rookie campaign.

Keuchel did work five shutout innings against the Yankees in his last start on May 14. He’s 1-0 with a 1.64 ERA over his past two starts. Keuchel is 1-1 with an 11.57 ERA in two road starts.

He’s 4-4 with a 2.06 ERA in 10 career starts against the Yanks. At Yankee Stadium, Keuchel is 3-2 with a 2.43 ERA in six starts.

Keuchel vs Cortes

Dallas Keuchel
VS
Nestor Cortes
2-3 Record 2-1
5.54 ERA 1.35
3.98 xERA 2.17
1.96 WHIP 0.85
1.07 SO/W Ratio 4.45

New York lefty Nestor Cortes is 2-1 over his last four starts. He got the win over the White Sox in May 15, allowing three hits and one earned run on a solo homer over eight innings.

Cortes has worked into the eighth inning in each of his last two starts, allowing just that one earned run over the course of 15.1 innings pitched.

In his second stint with the Bronx Bombers, Cortes is 9-5 over his career with the Yanks. He’s 3-0 in three career appearances against the White Sox, two of them starts. His ERA over 19 innings of work when facing the ChiSox is 1.89.

Batting Average vs Starting Pitchers

Yankees Batters Batting Average vs Keuchel White Sox Batters Batting Average vs Cortes
Josh Donaldson .237 Jose Abreu .286
Joey Gallo .200 Tim Anderson ..375
Marwin Gonzalez .000 Adam Engel .333
Aaron Hicks .125 Leury Garcia .200
Kyle Higashioka .000 Yasmani Grandal .000
Aaron Judge .308 Josh Harrison .000
Isiah Kiner-Falefa .385 Reese McGuire .250
DJ Lemahieu .250 Yoan Moncada .333
Anthony Rizzo .167 AJ Pollock .000
Ginacarlo Stanton .545 Luis Robert .167
Gleyber Torres .400 Gavin Sheets .000
Jose Trevino .000 Andrew Vaughn .167

Yankees DH Giancarlo Stanton is 6-for-11 (.545) with two homers and 5 RBI off of Keuchel. Gleyber Torres is 4-for-10 (.400) off of Keuchel with two RBI.

Both Isiah Kiner-Falefa (5-for-13, 385) and Aaron Judge (4-for-13, .308) have also hit Keuchel well. Josh Donaldson has taken Keuchel deep twice.

For the White Sox, Tim Anderson is 3-for-8 (.375) against Cortes. Adam Engel and Yoan Moncada are both 1-for-3 (.333). Engels’ hit was a solo homer. Andrew Vaughan also hit a solo shot off Cortes.

White Sox vs Yankees Prediction

Keuchel traditionally pitches well against the Yankees. Cortes currently is pitching well against everybody.

Go with the home team on this one.

Pick: New york Yankees ML (-220)

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