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Week 2 College Football Picks Against the Spread

Brady Trettenero

by Brady Trettenero in College Football

Updated Sep 4, 2024 · 11:10 AM PDT

Texas Longhorns quarterback Quinn Ewers snaps the ball
Texas Longhorns quarterback Quinn Ewers (3) snaps the ball during the game against Colorado State at Darrell K Royal-Texas Memorial Stadium in Austin Saturday, Aug. 31, 2024.
  • Browse our Week 2 college football picks against the spread for Saturday (Sep. 7)
  • We went 3-0 on CFB ATS picks last weekend and are 5-1 on the season
  • Below, see my best Week 2 college football picks against the spread

Week 2 of the 2024 college football season features a marquee Michigan vs Texas showdown, plus several other games that offer ATS betting value. We’ve gathered our three top CFB picks against the spread to help you turn a profit.

Among our top college football picks against the spread this weekend is a play on Steve Sarkisian’s Longhorns as they aim to cover against the Wolverines in Ann Arbor. We’re also taking an intriguing Big Ten underdog against a Big 12 contender.

Let’s dive into our expert college football picks against the spread for Week 2 (Saturday, September 7th).

Texas vs Michigan Odds

Team Spread Moneyline Total
Texas -7 (−112) −270 Over 42 (−112)
Michigan +7 (−108) +220 Under 42 (−108)

All odds as of September 4th at DraftKings Sportsbook. Check out the top USA betting sites for college football against the spread betting.

ATS Picks #1: Texas -7 (vs Michigan)

Kicking off my Week 2 college football picks against the spread is a play on Texas to cover -7 vs Michigan. The number is already climbing up from the -6.5 value it opened at, and it’s not hard to see why.

The Longhorns are coming off a dominant 52-0 win over Colorado State in Week 1, while the Wolverines struggled to put away Fresno State 30-10. Life after Harbaugh isn’t going to be easy for Michigan, and we’re seeing the impact of key offseason departures.

Michigan’s offense, in particular, looked out of sorts against the Bulldogs. New starting QB Davis Warren went just 15-for-25 for 118 yards and an interception. If not for a historic performance from kicker Dominic Zvada, who hit field goals from 45, 53, and 55 yards out, the final score would have been much closer.

YouTube video

The Wolverines will have an even tougher time moving the ball against Texas’ stout defense. The Longhorns held Colorado State to a mere 192 total yards in the opener and boast one of the best secondaries in the nation, anchored by star cornerback Jahdae Barro.

Texas QB Quinn Ewers looked sharp in his 2024 debut, tossing four TDs to his new trio of explosive receivers. While Michigan does have the best cornerback in the country in Will Johnson, the Wolverines’ secondary has several new pieces and will take time to fully mesh together.

It’s evident that Warren is a notable drop-off from JJ McCarthy at Michigan. I simply don’t see the Wolverines having enough firepower to hang with Texas despite the game being played in Ann Arbor.

  • Pick: Texas -7 (-112)

Kansas vs Illinois Odds

Team Spread Moneyline Total
Kansas -5.5 (−108) −218 Over 56 (−108)
Illinois +5.5 (−112) +180 Under 56 (−112)

ATS Picks #2: Illinois +5.5 (vs Kansas)

Another addition to my Week 2 college football picks against the spread is Illinois to cover against Kansas in a Big 12-Big Ten showdown. Memorial Stadium should be rocking for this primetime matchup on FamILLy Weekend.

I think the Fighting Illini rushing defense will be the difference-maker in this one. They allowed only 49 rushing yards to Eastern Illinois in the opener, just one year after allowing only 129.1 yards per game (32nd nationally) last season.

Illinois matches up well against a Kansas offense that relies heavily on the run game behind star RB Devin Neal. Bret Bielema’s team is also 9-3 against the spread in its last 12 games as a home underdog of five or more points.

Offensively, Illinois QB Luke Altmyer was sharp in Week 1, throwing for 213 yards and 4 TDs. The additions of WRs Pat Bryant and Malik Elzy give the Illini more explosive weapons on the outside. Kansas, meanwhile, allowed 7.6 passing yards per attempt last year, placing them bottom of the half in the Big 12.

While the Jayhawks are the more talented team, the combination of Illinois’ strong run defense, home-field edge, and improved passing game gives them a great shot to keep this one close as 5.5-point underdogs.

  • Pick: Illinois +5.5 (-112)

Mississippi State vs Arizona State Odds

Team Spread Moneyline Total
Mississippi State +6.5 (−112) +200 Over 59.5 (−110)
Arizona State -6.5 (−108) −245 Under 59.5 (−110)

ATS Picks #3: Arizona State -6.5 (vs Mississippi State)

Concluding my Week 2 college football picks against the spread is a play on Arizona State to cover -6.5 vs Mississippi State.

The Sun Devils looked impressive on both sides of the ball in their 48-7 blowout win over Wyoming in Week 1. ASU racked up 499 total yards of offense, averaging 7.0 yards per play. Defensively, they held the Cowboys to a mere 118 total yards and forced three turnovers.

Playing at Mountain America Stadium should provide a nice boost for Arizona State. With a raucous crowd expected for this primetime kickoff, Mississippi State QB Blake Shapen will face a tough road environment in his first road start of 2024.

While the Bulldogs put up 56 points in their opener against Eastern Kentucky, it’s hard to glean too much from a game against an FCS opponent. Mississippi State is starting eight new transfers on offense and ranked ninth-last in the Power 5 in terms of EPA per play last year.

The Bulldogs may experience some growing pains, especially on the road against an Arizona State defense that looked dominant in Week 1. I like the Sun Devils to cover on the strength of their stingy defense and explosive offense.

  • Pick: Arizona State -6.5 (-108)

Brady’s 2024 CFB ATS Picks Record: 5-1

 

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