Eagles vs Packers Picks & Closing Odds

• The Green Bay Packers are 1-point favorites over the Philadelphia Eagles on MNF
• Eagles’ WR AJ Brown (hamstring) will play with no restrictions
• Keep reading for my Eagles vs Packers picks and predictions, plus closing odds

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It’s a potential NFC Championship game preview on Monday night, as the Philadelphia Eagles (6-2, 5-3-0 ATS) visit the Green Bay Packers (5-2-1, 3-5-0 ATS).

The Eagles have won three straight in this head-to-head, yet are slight road ‘dogs in the NFL odds. Kickoff is set for 8:15pm ET from Lambeau Field in Green Bay, WI, with ABC and ESPN carrying the broadcast.

Eagles vs Packers Picks & Prediction

• Philadelphia Eagles moneyline (-106) at FanDuel

The Eagles have been dinged over the last few years for their inconsistency, but they’ve been doing it while winning, and even have a Super Bowl title for it.

The Packers, though, seem to have that same lackadaisical DNA in their system, only they don’t have any title pedigree to speak of in the Matt LaFleur-Jordan Love era.

A team that ranks top five in yards per play, third down success rate and converts 72% of red zone trips to touchdowns should not be slinging in the mud with a team like the Panthers and losing 16-13 as nearly two TD favorites. 

THE PANTHERS BEAT THE PACKERS ON A GAME-WINNING FIELD GOAL! 🔥

(via @NFL) pic.twitter.com/MWVTdkSSIj

— SportsCenter (@SportsCenter) November 2, 2025

Perhaps playing the champs lifts their attention and focus, and it should: after a hangover-ish start to the year, Philly has put together two standout performances before heading into the bye.

In their 28-22 win over the Vikings, Jalen Hurts had his best passing day by stats and optics, throwing for 326 yards and three TD’s with no interceptions. 

The following week, Saquon Barkley broke out, busting the game open with a season-best 65-yards TD rumble, part of a 150-yard, 2-TD afternoon in a 38-20 demolition of the Giants.

SAQUON GONE ON SECOND PLAY.

NYGvsPHI on FOX/FOX Onehttps://t.co/HkKw7uXVnt pic.twitter.com/PbcWnvKV2E

— NFL (@NFL) October 26, 2025

Teams that get embarrassed like the Packers did are usually strong candidates for a bounce back: consider that over the past 20 seasons, teams upset as a double-digit favorite are 47-29-1 ATS the next game.

Still, my Eagles vs Packers prediction is to take the champs on the moneyline. Without Kraft, Green Bay doesn’t have a go-to receiver for Love, and plenty of them are dinged up, with Savion Williams (foot), Dontayvion Wicks (calf) and Matthew Golden (shoulder) all questionable right up to kickoff. 

The Eagles are 6-2-0 as a betting favorite this year, and 3-1 away from home. They’re playing at the right level for this matchup of NFC title contenders.

Eagles vs Packers Closing Lines

Closing in on two hours before kickoff, the Packers are slight -110 moneyline favorites, and just a 1-point favorite on the spread at bet365.

Over at FanDuel, you can grab the Eagles as +1.5-point underdogs and at -106 on the moneyline. The best total for the Over is currently 44.5 points, while Under bettors can find the Over at 46.5 points at DraftKings.

The interactive table above will automatically update as the NFL betting odds move over the course of the day.

Eagles vs Packers Line Movement

If ever there was a line that was in flux, Eagles-Packers is it. Just hours before kickoff, you can find both the Eagles and the Packers as favorites, depending where you do your betting.

What we do know is the the Eagles have been as low as 3-point underdogs, to favored by as much as 1.5 points at certain books. 

Most bet on #NFL Anytime TD Scorers for Eagles vs Packers at @DKSportsbook 🎟️

1. Saquon Barkley (-105)
2. Josh Jacobs (-155)
3. Jalen Hurts (+100)
4. Dallas Goedert (+230)
5. AJ Brown (+165) pic.twitter.com/n03dkj8IzV

— SportsBettingDime (@SBD) November 10, 2025

Two things might have flipped this: first, AJ Brown (hamstring), who missed Philly’s last game against the Giants is a full go, as is Saquon Barkley (groin).

Second is perhaps Green Bay looking so uninterested in their home loss to the Carolina Panthers last time out. In that game, they also lost their leading receiver Tucker Kraft to a season-ending knee injury.

The moneyline movement mirrors the spread, as the Eagles are now essentially side-by-side with the Packers in the -110 to -120 range. They started as distant as +140. It was a less significant move for the Pack, who started as -140 favorites.

Not a ton has messed with the total, as it’s been mostly in the 45-point range.

The public loves the Eagles and Over 45.5 on Monday Night Football 👀

The latest Eagles vs Packers betting splits 👇 pic.twitter.com/G0PRl5fETr

— SportsBettingDime (@SBD) November 10, 2025

Looking at the NFL public betting percentages, and they’re leaning to the visitors on the spread, with 79% of the bets and 78% of the money on the Eagles.

The public is betting Philly as an outright winner as well, with 80% of the money on an Eagles win, taking slightly less of the bets at 72%.

Big money is also on the Over, with 80% wanting the two teams to cross the 45.5-point line, though just 54% of the bets taking the Over. Forty-six percent of the bets are on the Under, but only 20% of the money.

PHI vs GB Betting Trends

• Under Nick Sirianni, the Eagles are 15-4-0 against the spread when the line is between +3 and -3, including 11-1-0  ATS since 2022. 
• The Eagles are 9-3 ATS on the road since the start of last season. They have won seven straight against teams with winning records.
• The Packers are 1-5-0 ATS in their past six games, and they are 1-4-0 ATS against the Eagles over the last five meetings.