NFL Divisional Round Playoff Odds – Opening Betting Lines & Spread for All Games

• The divisional round of the NFL Playoffs will be played next Saturday and Sunday
• The Eagles, the NFC’s #1 seed, have opened as 8.5-point home favorites over the Giants
• A look at the NFL Playoffs division round odds can be found below with early predictions

Three of the four matchups for the divisional round of the NFL Playoffs have been set.

The Philadelphia Eagles (14-3) will host the New York Giants (10-7-1) at 8:15 p.m. ET Saturday at Lincoln Financial Field and have opened as 8.5-point favorites. The Eagles are the #1 seed in the NFC and the Giants are seeded #6.

On Sunday, the Giants upset the #3 seed Minnesota Vikings 31-24 in Minneapolis in a wild-card game. The Eagles drew a bye by virtue of having the best record in the NFC.

The #2 San Francisco 49ers (14-4) will host either the #5 Dallas Cowboys (13-5) in the other NFC game at 6:30 p.m. ET Sunday. The Cowboys beat the #4 Tampa Bay Buccaneers 31-14 on the road on Monday night.

In the AFC the #1 seed Kansas Chiefs (14-3) will host the #4 Jacksonville Jaguars (10-8) at 4:30 p.m. ET Saturday and the #3 Cincinnati Bengals (13-4) will visit the #2 Buffalo Bills (14-3) at 3 p.m. ET Sunday

The Chiefs drew a bye after having the AFC’s top record while the Jaguars beat the #5 Los Angeles Chargers 31-30 on Saturday in a wild-card game. On Sunday, the Bills downed the #7 Miami Dolphins 34-31, and the Cincinnati Bengals defeated the #6 Baltimore Ravens 24-17 in wild-card games.

The Bills are 3.5-point favorites and the Chiefs are 8.5-point picks.

NFL Divisional Playoff Opening Odds

Odds as of January 15th and 16th at FanDuel Sportsbook.

Giants vs Eagles Early Odds & Predictions

The NFC East rivals will be meeting for the third time this season. The Eagles swept the regular-season series, winning 48-22 on the road on Dec. 11 and 22-16 at home on Jan. 8 in the regular-season finale when the Giants rested their regulars.

Daniel Jones led the Giants over the Vikings on Sunday by throwing for 301 yards and two touchdowns. He also ran 15 times for 79 yards in his first career playoff game.

KEEP 'EM COMING 🥵

📺: FOX pic.twitter.com/sj04DxCfd2

— New York Giants (@Giants) January 15, 2023

Saquon Barkley rushed for two touchdowns in the first postseason game of his career. Isaiah Hodgins and Daniel Bellinger caught TD passes.

The Eagles have many playmakers, including Jalen Hurts whose 3,701 passing yards was 10^th in the NFL in the regular season. A.J. Brown (1,496) was fourth in receiving yards and Miles Sanders (1,269) finished fifth in rushing yards.

The Eagles are awfully good, but the Giants are good enough to at least sneak under the number.

Pick: Giants +8.5 (-114)

Cowboys vs 49ers Early Odds & Prediction

The 49ers bring an 11-game winning streak into the game while the Cowboys have won seven of their last nine games after beating the Buccaneers on Monday night.

Rookie quarterback Brock Purdy threw three touchdown passes and ran for another as the 49ers beat the Seahawks on Saturday. San Francisco has won six straight games since Purdy replaced an injured Jimmy Garoppolo.

Purdy threw for 332 yards, the second-highest total for a rookie QB in an NFL playoff game. Russell Wilson had 385 yards for the Seahawks against the Atlanta Falcons in 2012.

Dak Prescott completed 25 of 33 passes for 303 yards and four touchdowns to lead the Cowboys on Monday night. Most importantly, he did not have a turnover for the first time in eight games.

The Cowboys won even though kicker Brett Maher set an NFL Playoffs record by missing four extra points.

The Cowboys played well at Tampa, but San Francisco is rolling behind Purdy and isn’t going to be stopped by Dallas.

Pick: 49ers -4.5 (-110)

Bengals vs Bills Early Odds & Prediction

The teams’ regular season meeting on Jan. 1 in Cincinnati was ruled no contest following the scary situation in which Bills safety Damar Hamlin went into cardiac arrest on the field.

The Bengals’ Sam Hubbard returned a Tyler Huntley fumble 98 yards for a touchdown in the fourth quarter Sunday night to break a 17-17 tie and give Cincinnati the win over the Ravens.

NO WORDS.#BALatCIN | 📺 NBC pic.twitter.com/pAFTy1yqpS

— Cincinnati Bengals (@Bengals) January 16, 2023

Joe Burrow passed for 209 yards and a TD for the Bengals. In addition to forcing the fumble, Cincinnati also intercepted Huntley once.

Josh Allen had three turnovers but made up for it by throwing two touchdown passes in a 3:11 span of the third quarter to rally the Bills to victory over the Dolphins.

Allen hit Cole Beasley for a 6-yard score then connected with Gabe Davis on a 23-yard TD. That put the Bills ahead 34-24 after they had squandered a 17-0 lead.

Both teams are hot as the Bengals have won nine games in a row and the Bills are on an eight-game winning streak. Home-field advantage in frigid Buffalo should make the difference.

Pick: Bills -3.5 (-105)

Jaguars vs Chiefs Early Odds & Prediction

Trevor Lawrence followed four interceptions with four touchdowns as the Jaguars overcame a 27-0 deficit to beat the Chargers on Saturday night.  It was the third-largest comeback in a playoff game in NFL history.

Riley Patterson’s 36-yard field goal on the final play gave the Jaguars their sixth straight victory. Travis Etienne helped set up the winning kick with a 25-yard run on fourth-and-1.

Chiefs quarterback Patrick Mahomes threw for an NFL-best 5,250 yards in the regular season. Tight end Travis Kelce’s 1,338 receiving yards were eighth in the receiving yardage.

The Chiefs being the #1 seed in the AFC speaks for itself, but the Jaguars have a lot of mojo going for them right now and should hang tough.

Pick: Jaguars +8.5 (-105)