Upcoming Match-ups

Opening College Football Week 3 Odds, Spreads and Early Predictions

John Perrotto

by John Perrotto in College Football

Sep 11, 2022 · 12:55 PM PDT

Miami Hurricanes wide receiver Key'Shawn Smith celebrates his touchdown against the Southern Miss Golden Eagles
Sep 10, 2022; Miami Gardens, Florida, USA; Miami Hurricanes wide receiver Key'Shawn Smith (5) celebrates his touchdown against the Southern Miss Golden Eagles during the second half at Hard Rock Stadium. Mandatory Credit: Jasen Vinlove-USA TODAY Sports
  • Florida-Louisville kicks off Week 3 of the college football season Friday
  • #13 Miami visits #24 Texas A&M on Saturday
  • A look at all Week 3 opening lines can be found below

Week 3 of the college football season kicks off Friday night when Florida State visits Louisville and Wyoming hosts Air Force.

There will be two games between ranked teams on Saturday. #13 Miami travels to #24 Texas A&M and #12 BYU visits #25 Oregon.

All the Week 3 opening lines can be found in the college football odds:

College Football Week 3 Opening Odds

Game Time (Eastern) Team Spread Moneyline
Friday, Sept. 16 Florida State Pick (-110) OFF
7:30 p.m. Louisville Pick (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Friday, Sept. 16 Air Force -14.5 (-110) OFF
8 p.m. Wyoming +14.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Texas State +31.5 (-110) OFF
12 p.m. Baylor -31.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Western Kentucky +6.5 (-110) OFF
12 p.m. Indiana -6.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Connecticut +47 (-110) OFF
12 p.m. Michigan -47 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Purdue -2 (-110) OFF
12 p.m. Syracuse +2 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Georgia -23 (-110) OFF
12 p.m. South Carolina +23 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Oklahoma -9.5 (-110) OFF
12 p.m. Nebraska +9.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Ohio +21.5 (-1100 OFF
2 p.m. Iowa State -21.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Rutgers OFF OFF
2 p.m. Temple OFF OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 South Alabama +15 (-110) OFF
2 p.m. UCLA -15 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Old Dominion +10 (-110) OFF
2 p.m. Virginia -10 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 California +13 (-110) OFF
2:30 p.m. Notre Dame -13 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Tulane +15.5 (-110) OFF
3 p.m. Kansas State -15.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Penn State -2.5 (-110) OFF
3:30 p.m. Auburn +2.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Colorado +25.5 (-110) OFF
3:30 p.m. Minnesota -25.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Vanderbilt +2.5 (-110) OFF
3:30 p.m. Northern Illinois -2.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 New Mexico State +38 (-110) OFF
3:30 p.m. Wisconsin -38 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 BYU +3.5 (-110) OFF
3:30 p.m. Oregon -3.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Ole Miss -13.5 (-110) OFF
3:30 p.m. Georgia Tech +13.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 UL-Monroe +50 (-110) OFF
4 p.m. Alabama -50 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Kansas +9 (-110) OFF
4 p.m. Houston -9 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Liberty +16 (-110) OFF
5 p.m. Wake Forest -16 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Colorado State +16.5 (-110) OFF
5 p.m. Washington State -16.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Mississippi State -2.5 (-110) OFF
6 p.m. LSU +2.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Texas Tech +9.5 (-110) OFF
7 p.m. NC State -9.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Toledo +30 (-110) OFF
7 p.m. Ohio State -30 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Akron +45.5 (-110) OFF
7 p.m. Tennessee -45.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 South Florida +24 (-110) OFF
7:30 p.m. Florida -24 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Nevada +20.5 (-110) OFF
7:30 p.m. Iowa -20.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 SMU +2.5 (-110) OFF
7:30 p.m. Maryland -2.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Michigan State -1 (-110) OFF
7:30 p.m. Washington +1 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Pittsburgh -10 (-110) OFF
7:30 p.m. Western Michigan +10 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Louisiana Tech +36 (-110) OFF
8 p.m. Clemson -36 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 UTSA +14 (-110) OFF
8 p.m. Texas -14 (-1100 OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Miami +5.5 (-110) OFF
9 p.m. Texas A&M -5.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 San Diego State +19.5 (-110) OFF
10 p.m. Utah -19.5 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Fresno State +15 (-110) OFF
10:30 p.m. USC -15 (-110) OFF
Game Time (Eastern) Team Spread Moneyline
Saturday, Sept. 17 Eastern Michigan +20 (-110) OFF
11 p.m. Arizona State -20 (-110) OFF

Odds as of September 11th at DraftKings Sportsbook. Get this DraftKings promo code to bet on college football. 

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Not So Big Showdown Now

Miami (2-0) visits Texas A&M (1-1) on Saturday but it won’t be an expected early-season matchup of unbeaten teams. The Aggies are 5.5-point favorites.

Texas A&M (1-1) was upset by Appalachian State 17-14 at home Saturday. The Aggies had a chance to tie the game with about 3.5 minutes to go but Caden Davis was short on a 47-yard field goal attempt.

Devon Achane scored both touchdowns for Texas A&M on a 26-yard run and 95-yard kickoff return. Haynes King passed for just 97 yards, completing 13 of 20 attempts.

Miami (2-0) sputtered early before being Southern Mississippi 30-7 at home. The Hurricanes fell behind 7-3 before scoring the last 27 points.

Henry Parrish rushed for 97 yards and one touchdown in a winning effort. Tyler Van Dyke was 20 of 29 passing for 253 yards and a TD.

Texas A&M was exposed as an overrated team by App State. Look for Miami to at least be good with the points if not win the game outright.

Pick: Miami +5.5 (-110)

Big Game Out West

BYU visits Oregon in an interesting non-conference game between two of the better teams in the West. The Ducks have opened 3.5-point favorites.

On Saturday night, BYU (2-0) won a double-overtime thriller as it got past visiting Baylor 26-20.  Lopini Kotoa scored the winning touchdown on a 3-yard run then the Cougars’ defense held the Bears to end the game.

Jaren Hall had 261 yards passing and one touchdown while also having a 22-yard scoring catch. Chase Roberts had eight receptions for 122 yards and a TD.

Oregon (1-1) bounced back from a drubbing by Georgia in its opener to blow out Eastern Washington of the FCS 70-14 on Saturday.

Bo Nix starred in the rout as the Auburn transfer threw for 277 yards and five touchdowns. Troy Franklin had 10 receptions for 84 yards a TD as the Ducks assured themselves of taking a 20-game winning streak at Autzen Stadium into the matchup with BYU.

It is still difficult to get past Oregon getting thumped 49-3 by Georgia. BYU is a quality team and could win this game outright.

Pick: BYU +3.5 (-110)

That’s Out of Line

Everyone is down on Notre Dame right now and justifiable so. The Fighting Irish are 0-2 under new coach Marcus Freeman and coming off an ugly home loss to Marshall on Saturday.

Notre Dame hosts California (2-0) on Saturday are 13-point favorites. Look for the line to go up. Notre Dame is still a very talented team and a national brand while Cal’s wins have been against lightweight competition in UC Davis and UNLV.

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