Lions vs Packers Odds, Lines, and Spread for Week 2 Monday Night Football

By Eric Rosales in NFL Football
Updated: September 20, 2021 at 4:52 am EDTPublished:

- The Green Bay Packers try to bounce back after Week 1 stunner as they host the Detroit Lions
- Monday Betting Record: 0-0 ML; 0-1 ATS; 0-0 O/U; -1 units
- Check below for all the odds and trends for this MNF Week 2 clash
After a Week 1 demolition at the hands of the New Orleans Saints, Aaron Rodgers and the Green Bay Packers should be able to rebound in Week 2.
Right?
That’s the big question as the Pack hosts the Detroit Lions on Monday Night Football.
Oddsmakers believe it was just a blip, making Green Bay a whopping 12-point favorite in this one.
Kickoff is at 8:15pm ET from Lambeau Field, where it’s expected to be a 82 degrees and clear.
Lions vs Packers Odds
Team | Spread | Moneyline | Total |
---|---|---|---|
Detroit Lions | +12 (-110) | +425 | O 48 (-115) |
Green Bay Packers | -12 (-110) | -105 | U 48 (-105) |
*Odds taken on September 19 from DraftKings
Rodgers, Offense Need to Pick Up Pace
It was an historic beating Rodgers and the Pack took against the Saints. The 38-3 drubbing was the largest margin of defeat a Rodgers-led team has suffered.
But his performance: 15-for-29 for 133 yards, no TD’s and two interceptions was far from the only lackluster effort. Credit Matt LaFleur for eating the blame for the Packers’ lack of running game. Green Bay put up the fewest rushing yards (43) and second-least carries (15) of any team in Week 1.
Aaron Rodgers ends Week 1 as QB 35 in fantasy points.
Only 32 teams played. pic.twitter.com/OpqUHrNwrR
— Matthew Berry (@MatthewBerryTMR) September 14, 2021
Aaron Jones was literally missing in action, carrying five times for nine yards as the Pack abandoned the run after falling behind so early.
Davante Adams was also neutralized, hauling in five balls for 56 yards and was targeted just seven times. For reference, Adams had only two games last season lower than that figure, and had double-digit targets 12 times last year.
Aaron Jones balled out last season. 🔥@Showtyme_33 | #GoPackGo pic.twitter.com/A3A8AuoJ3h
— GBP Daily – Rob Westerman lll (@GBPdaily) March 4, 2021
It’s safe to say all three are welcoming in their division foe. Rodgers is 9-2 in 11 home starts against the Lions, tossing 21 touchdowns against just four interceptions. Jones’ last outing at home against Detroit was spectacular, running for 168 yards, catching four balls for 68 yards and finding paydirt three times in a 42-21 rout.
Adams has all the makings of a breakout too. With Lions’ top corner Jeff Okudah out for the year (Achilles), the unproven trio of Amani Oruwariye, Ifeatu Melifonwu and A.J. Parker will try their best to contain PFF’s top graded receiver from a year ago. Gulp.
Can Lions Stay Competitive?
The Lions were dominated for much of their Week 1 loss to the 49ers, at one point down 38-10. Somehow, Dan Campbell’s club rallied, and made came up just short in a 41-33 loss. More importantly, though, the Lions crushed all parlays with an obscene backdoor cover.
49ers LB Dre Greenlaw picks off Jared Goff and runs it back for 6 💨
(via @NFLBrasil)
pic.twitter.com/OY6zo67Ps8— Bleacher Report (@BleacherReport) September 12, 2021
There’s a possibility this game follows a similar script. It’s expected that Detroit will be playing a lot of catch up in this one, and Jared Goff actually did a very fine facsimile of the Matthew Stafford ‘hopeless but gutsy’ effort we’ve come to know out of this franchise.
Goff completed 38-of-57 for 338 yards and three touchdowns, though he did throw a backbreaking pick-6.
He could use the support of his backfield, including ex-Packer Jamaal Williams and second-year man D’Andre Swift, though both were on the injured list this week.
Jamaal Williams punches it in from the 1! First touchdown for Jamaal on the #Lions. #BYUFootball
— Cougs in the Pros 🤙🏼 (@BYUpros) September 12, 2021
Williams had 110 total yards and a touchdown on 17 touches in his first game with the Lions. Swift chipped in 104 yards on 19 total touches and a score of his own.
Part of the reason for the Saints’ success — and Jameis Winston throwing for five scores — was a dominant running game, which bullied Green Bay’s defensive front to the tune of 171 yards.
A big piece of that Green Bay defense will also not be available, as edge rusher Za’Darius Smith is on the shelf with a bad back.
What’s the Best Bet?
The early season mismatch, coupled with a poor Packers’ performance and frisky Lions’ cover could have you thinking about taking all those points. But don’t go down that road.
The Packers have yet to lose back-to-back games in the LaFleur era, and they’re 8-1 ATS in their last nine outings following a loss.
Last season, their average margin of victory following a loss was 16 points.
Expect Rodgers to put together another tormenting performance against his division rival, and for the drama to subside in Green Bay — for at least a week.
Pick:
- Packers -12 (1 unit to win 0.91 units )
- OVER 48 points (1 unit to win 0.87 credits)

Sports Writer & Editor
Having worked in and around sports since 1997, Eric is truly a knowledgeable expert. The two-time journalism grad specializes in all things NBA and NFL. From TSN.ca to CTV's Olympic Broadcast Consortium, Eric's work has appeared in local and national publications alike.