Liverpool vs Atletico Madrid Odds, Preview & Best Bet – UCL Group Stage Matchday 4

By Daniel Coyle in Soccer News
Published:

- Liverpool FC aims to extend their perfect record in UEFA Champions League play when they host Atletico Madrid on Wednesday as betting favorites.
- The Reds have avoided defeat in 15 overall matches this season and will face a slumping Atletico squad that will be missing French veteran Antoine Greizmann
- Read on for all the odds and trends ahead of Wednesday afternoon’s Group B clash at Anfield
Liverpool FC will be looking to remain undefeated in UEFA Champions League group stage action when they play host to Atletico Madrid on Wednesday as strong -155 favorites. While the Reds have already clinched a berth in this season’s knockout stage, Atletico Madrid remains in a desperate battle for second place on the Group B table as they travel to Liverpool pegged as lengthy +425 underdogs.
Here’s a look at all the odds, trends, and best bets ahead of this Champions League Group B matchup, set for 4:00 pm ET on Wednesday afternoon at Anfield.
Liverpool vs Atletico Madrid Odds
Matchup | Spread | Moneyline | Total |
---|---|---|---|
Liverpool FC vs Atletico Madrid | LIV -0.5 (-150) | ATL +0.5 (+130) ( | LIV -155 | Draw +320 | ATL +425 | Ov 2.5 (-135) | Un 2.5 (+110) |
Odds at DraftKings as of November 2
Liverpool FC Outlook
Liverpool FC have been on a mission this season after making an early exit from the Champions League and settling for a third-place finish on the Premier League table last season. The club has avoided defeat in 15 matches across all competitions so far this season, lifting them back into EPL title contention, and making them one of just two clubs so far to lock up a berth in the Champions League knockout stage.
FULL-TIME Liverpool 2-2 Brighton
A thrilling four-goal draw ends with goals from Jordan Henderson and Sadio Mane for the Reds, and Enock Mwepu and Leandro Trossard for the Seagulls#LIVBHA pic.twitter.com/shrzuu1KnU
— Premier League (@premierleague) October 30, 2021
The Reds have maintained that torrid pace in recent outings, scoring 22 times and keeping clean sheets on three occasions during a 4-1-0 win-draw-loss run that includes last month’s 3-2 win over Atletico. But while each of their four recent victories have come on the road, Liverpool has struggled to close the deal in recent dates at Anfield, settling for 2-2 draws with Manchester City and Brighton in their past two league contests on home turf.
The Reds have also turned in middling results in recent home dates with Madrid, going 1-2-1 over their past four non-friendly meetings, and have failed to tally consecutive UCL wins on home turf during the same season since November 2019.
⚽️🅰️🅰️ vs Norwich
⭕️ vs Burnley
⚽️ vs Chelsea
⚽️ vs Leeds
⚽️ vs Milan
⚽️ vs Palace
⚽️ vs Brentford
⚽️⚽️ vs Porto
⚽️🅰️ vs Man City
⚽️🅰️ vs Watford
⚽️⚽️ vs Atlético
⚽️⚽️⚽️🅰️ vs Man Utd
🅰️ vs BrightonMohamed Salah has only failed to score or assist in ONE game this season.🤯#LFC pic.twitter.com/pxrlgIVQxT
— William Hill (@WilliamHill) October 30, 2021
It has been Mohamed Salah powering the vaunted Liverpool offense. The Egyptian superstar has potted six goals over his past four outings, including a two-goal performance in last month’s 3-2 victory over Atletico. Not surprisingly, Salah leads all players on the player props as a short -105 bet to score anytime, and as a +280 wager on both the first scorer and last scorer odds.
Liverpool vs Atletico Madrid Head-to-Head Stats
9 | Matches played | 9 |
2 | Matches won | 5 |
2 | Matches drawn | 2 |
5 | Matches lost | 5 |
11 | Goals scored | 13 |
8 | Points | 17 |
Atletico Madrid Outlook
Unlike Liverpool, it has been far from smooth sailing for Atletico Madrid so far this season. The club has struggled to produce consistent results in all competitions, tallying consecutive wins just once since opening their campaign on a solid 3-1-0 run. Last weekend’s 3-0 rout of Real Betis in La Liga play marks the club’s most decisive victory of the season and provides a glimmer of hope ahead of Wednesday’s visit to Liverpool.
After the first three matches, this is the table for Group B.
After Porto defeated AC Milan 1-0 this morning, Liverpool is looking the goods to qualify into the knockout stages.#UCL pic.twitter.com/entAuzGU8T
— The Broadcast Booth (@TBB_AUS) October 19, 2021
Sunday’s victory featured João Félix’s first goal of the season after being held scoreless through eight overall appearances. Atletico will likely need more of the same from the young Portuguese striker, as well as from Uruguayan veteran Luis Suarez if they are to have any chance on Wednesday in the absence of Antoine Greizmann.
The French star has been one of the few bright spots on an otherwise moribund Atletico attack, scoring three total goals in his past four overall appearances, and also netted both goals in the club’s 3-2 loss to the Reds on Matchday 3. However, Griezmann also earned himself a red card in last month’s loss to Liverpool, which will keep him out of Wednesday’s contest.
Antoine Griezmann sent off with a red card against Liverpool 😳 pic.twitter.com/m9OCz0n9ab
— CBS Sports Golazo ⚽️ (@CBSSportsGolazo) October 19, 2021
That puts enormous pressure on Suarez, who currently leads the club with six goals in league play this season. However, the 34-year-old’s marker in Atletico’s narrow 2-1 win over AC Milan back in September marks his only goal in nine UCL contests since August 2020. That slump has contributed to the club’s current shaky position on the Group B table, where they currently deadlocked with Porto with a 1-1-1 record.
The Picks: Liverpool -1.5 (+205); BTTS No Draw +145

Sports Writer
Daniel has been writing about sports and sports betting for over 23 years. The seasoned pro has contributed to the likes of Sports Illustrated, Sportsnet, NESN, Bleacher Report, OddsShark, the Globe and Mail, and The Nation magazine.