Karen Khachanov vs Novak Djokovic Odds & Prediction – Astana Open Quarterfinals

By Quinn Allen in Tennis
Published:

- Karen Khachanov and Novak Djokovic meet in the Astana Open quarterfinals on Friday morning
- Djokovic is a heavy -715 moneyline favorite
- What’s the best bet for this match? Read on for the odds, preview and Khachanov vs Djokovic prediction
We’re into the last eight at the Astana Open in Kazakhstan, with world No. 1 Carlos Alcaraz already out. That leaves Novak Djokovic as the clear favorite to win the title as he faces US Open semifinalist Karen Khachanov in the quarterfinals on Friday, October 7th. The match gets started at 8:00 AM ET. Keep reading for the Khachanov vs Djokovic prediction.
Khachanov vs Djokovic Odds
Player | Spread | Moneyline | Total |
---|---|---|---|
Karen Khachanov | +2.5 (+220) | +500 | Ov 19.5 (-127) |
Novak Djokovic | -2.5 (-295) | -715 | Un 19.5 (+100) |
Odds as of October 6th at Barstool Sportsbook. Use this Barstool Sportsbook promo code to bet on the Astana Open quarterfinals
Djokovic is a clear favorite at -715 moneyline odds and for good reason. He’s 6-1 lifetime against Khachanov, already beating him twice this year in Belgrade and Dubai.

Karen Khachanov vs Novak Djokovic Betting Preview
It’s been a promising year for Khachanov, who made an impressive run to the semifinals at Flushing Meadows, even knocking out Nick Kygrios along the way. But, Casper Ruud proved to be too much for him in the end. Nonetheless, the Russian is playing good tennis at the moment and managed to eliminate a couple of solid opponents at the Astana Open.
Comeback Karen 🙌@karenkhachanov comes from a set down to defeat Cilic 2-6 6-3 6-3!#AstanaOpen pic.twitter.com/1mp4n3rBVr
— Tennis TV (@TennisTV) October 6, 2022
Khachanov beat American Maxime Cressy in the opening round in straight sets including a tiebreaker in the second then also took down Marin Cilic on Wednesday, 2-6, 6-3, 6-3. He was absolutely relentless in this match, saving 12 of 15 break points against a very experienced player on the tour. While it’s been a tough draw for Khachanov and it won’t get easier, he continues to flourish after the US Open. His only victory against Nole came in 2018 at the Rolex Paris Masters final in two sets.
Khachanov vs Djokovic Stats
18 | ATP Ranking | 7 |
4 | Career Titles | 89 |
31/21 | YTD Win/Loss | 28/6 |
1-6 | H2H Record | 6-1 |
The lack of consistent playing time doesn’t seem to be bothering Djokovic whatsoever. He just won yet another ATP title in Tel Aviv versus Cilic in straight sets and is now cruising his way through the Astana Open, notching six victories in a row heading into Friday. The Serb defeated Cristian Garin and Botic van de Zandschulp in the first two rounds, dropping just six games so far. He’s truly dominating in this tourney but Khachanov will be his toughest test yet.
7 quarter-finals in last 7 tournaments 🔥
Novak Djokovic moves forward in Astana with a 6-3 6-1 vs Botic Van De Zandschulp!
He meets Karen Khachanov for a semi-finals spot pic.twitter.com/UvV3PuFAGF
— We Are Tennis (@WeAreTennis) October 6, 2022
Djokovic won 37 of his service points against van de Zandschulp and looked very sharp with his first serve, posting a 78% conversion rate. The lack of game time at majors isn’t fazing Nole the least and it’s important to note he leads the H2H versus Khachanov 3-1 on indoor surfaces.
Khachanov vs Djokovic Prediction
There are no signs of Djokovic slowing down right now. Khachanov has given the Serb some problems indoors in the past and usually puts up a fight. Since the Russian is in top form at the moment, I give him a chance to win a set. Take Nole to win in three sets and progress to the semis, where he’ll face either Roberto Bautista-Agut or Daniil Medvedev.
Pick: Novak Djokovic to win in 3 sets (+295)
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Sports Writer
Quinn Allen is a sports journalist, with a background and education in broadcast journalism (BCIT '17). He is a full-time associate editor at ClutchPoints by day, where he writes about soccer, baseball, basketball, football, and more. At night, Quinn is a frequent contributor at SBD.