Stefanos Tsitsipas vs Daniil Medvedev Odds & Prediction – Australian Open Semifinals
By Stephanie Myles in Tennis
Updated: January 28, 2022 at 10:12 pm ESTPublished:
- The Australian Open semifinal between Stefanos Tsitsipas and Daniil Medvedev is a rematch of 2021
- Medvedev won that in straight sets – but Tsitsipas was coming off a statement win over Rafael Nadal
- Tsitsipas has won two of their last three meetings. We break down the matchup and make a prediction
Daniil Medvedev might have made a great escape from his quarterfinal quandary against Félix Auger-Aliassime – he is the only player in the Australian Open so far this year to have come back from a two-sets-to-none deficit.
But he remains the odds-on favorite to win the title this year. And his 6-2 record against semifinal opponent Stefanos Tsitsipas won’t do anything to dent his confidence.
Stefanos Tsitsipas vs Daniil Medvedev Odds
| Player | Spread | Moneyline | Total |
|---|---|---|---|
| [4] Stefanos Tsitsipas (GRE) | +3.5 (-110) | +190 | O 39.5 (-125) |
| [2] Daniil Medvedev (RUS) | -3.5 (-120) | -250 | U 39.5 (-105) |
Odds as of Jan. 27 at Caesars Sportsbook
Medvedev’s opponent Friday night in Melbourne (3:30 am ET) was a big question mark coming in. He had elbow surgery at the end of the 2021 season, and had only a short period to rehab and try to prepare for 2022.
- BETMGM SPORTSBOOK
USE CODE SBD1500 TO GET UP TO $1,500 PAID BACK
- BET365 SPORTSBOOK
BET $10 & GET $365 IN BONUS BETS WITH CODE DIME365
- THESCORE BET SPORTSBOOK
USE CODE DIME TO GET 100% BET RESET UP TO $1,000
- DRAFTKINGS SPORTSBOOK
BET $5 & GET $200 IN BONUS BETS INSTANTLY!
- FANDUEL SPORTSBOOK
GET $300 IN BONUS BETS EVERY DAY FOR 10 DAYS
- CAESARS SPORTSBOOK
USE CODE SBDDYW & DOUBLE YOUR WINNINGS ON YOUR FIRST 10 WAGERS!
- FANATICS SPORTSBOOK
GET 100% BET MATCH UP TO $100 FOR 10 DAYS
DRAFTKINGS T&Cs: GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-522-4700, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD). 21+ and present in most states. (18+ DC/KY/NH/PR/WY). Void in NH/OR/ONT/PR. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new customer. $5+ first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: sportsbook.draftkings.com/promos. Ends 4/6/26 at 11:59 PM ET. Sponsored by DK.
BET365 SPORTSBOOK T&Cs: GAMBLING PROBLEM? CALL OR TEXT 1-800-GAMBLER (AZ/CO/IL/IN/KS/KY/LA/MD/MO/NC/NJ/OH/PA/TN/VA) or 1-800-BETS OFF (IA). 21+ only (18+ KY). Must be present in AZ/CO/IA/IL/IN/KS/KY/LA (select parishes)/MD/MO/NC/NJ/OH/PA/TN/VA. Minimum $10 deposit required. Minimum odds -500 of greater. Bonus Bets wager excluded from returns. New customers only. T&CS, time limits and exclusions apply.
BETMGM SPORTSBOOK T&Cs: Gambling problem? Call 1-800-GAMBLER (Available in the US), Call 877-8-HOPENY or text HOPENY (467369) (NY), Call 1-800-327-5050 (MA), 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. This promotional offer is not available in DC, MS, NY, NV, ON, or PR.
He skipped his first scheduled singles match at the ATP Cup the first week of January. And he looked very, very flat through the first week of the Australian Open.
But as the second week has marched inexorably onwards, he has looked better and better. He’s looked like the No. 4 player in the world.
Stefanos Tsitsipas vs Daniil Medvedev Head-to-Head
| 23 (Aug. 12, 1998) | Age | 25 (Feb. 11, 1996) |
| Athens, Greece | Birthplace | Moscow, Russia |
| 6-4 | Height | 6-6 |
| 7 | Career ATP Singles Titles | 13 |
| 0 | Career Grand Slam Singles Titles | 1 |
| No. 3 (Aug. 9, 2021) | Career High Ranking | No. 2 (March 15, 2021) |
| No. 4 | Current Ranking | No. 2 |
| $16,345,212 | Career Prize Money | $16,345,212 |
| 6-1 | 2021 Won/Loss record | 7-1 |
| 2 | Career Head to Head | 6 |
Medvedev Survives Auger-Aliassime
The five-set marathon with Auger-Aliassime went 4h42. And after the 21-year-old Canadian won the first two sets with exceptional play against a struggling Medvedev, it felt all but over.
But Medvedev, an unorthodox player and a canny competitor, pulled everything out of his bag of tricks, saved a match point, and went on to victory.
"I asked myself 'what would Novak do?'" 😬
Fair to say Medvedev got a mixed reaction when he revealed his comeback inspiration! 😲#AusOpen – Live on Channel 9 and 9Now pic.twitter.com/WQRAgFtdu5
— Wide World of Sports (@wwos) January 26, 2022
He said after the match that he channeled the spirit of the absent Novak Djokovic.
What would Novak (or Roger, or Rafa) do? The Serb would find a way, thought Medvedev. And so did he.
Stefanos Tsitsipas vs Daniil Medvedev Match History
| Year | Tournament | Surface | Score | Winner |
|---|---|---|---|---|
| 2021 | French Open (QF) | Outdoor Clay | 6-3, 7-6 (3), 7-5 | Tsitsipas |
| 2021 | Australian Open (SF) | Outdoor Hard | 6-4, 6-2, 7-5 | Medvedev |
| 2019 | ATP Tour Finals (RR)) | Indoor Hard | 7-6 (5), 6-4 | Tsitsipas |
| 2019 | Masters Shanghai (SF) | Outdoor Hard | 7-6 (5), 7-5 | Medvedev |
| 2019 | Masters Monte Carlo (R16) | Outdoor Clay | 6-2, 6-1, 6-4 | Medvedev |
| 2018 | Basel (QF)2) | Indoor Hard | 6-4, 3-6, 6-3 | Medvedev |
| 2018 | US Open (R64) | Outdoor Hard | 6-4, 6-3, 4-6, 6-4 | Medvedev |
| 2018 | Masters Miami (R128) | Outdoor Hard | 2-6, 6-4, 6-2 | Medvedev |
A Long History Between Tsitsipas and Medvedev
Tsitsipas has won two of the last three meetings with Medvedev. But the two have a rather long history. And until the 2019 Tour Finals, the Russian had won five straight.
Guys! It’s happening! pic.twitter.com/Qdd0GIJZBW
— Alexis (@LexiDV) January 26, 2022
There has been some spice between the two, going all the way back to their first meeting in the first round of the Miami Masters in 2018.
Both have a little edge to them that could make for some fireworks in this one. Especially with so much at stake.
Expect the Greek star to pull out the serve-and-short-volley play to counter Medvedev’s tendency to play almost with his back to the wall on serve return.
Tsitsipas Blows Away Sinner
If Tsitsipas barely survived the considerable challenge of No. 20 seed Taylor Fritz in the round of 16, he was dominant in the quarterfinals against No. 11 Jannik Sinner, a 20-year-old expected to win his share of major titles in the near future.
But Sinner was not up to this encounter. And Tsitsipas never even gave him a sniff in a 6-3, 6-4, 6-2 victory that took just a shade over two hours.

At the round-of-16 stage of a major tournament, that is a light skate. And it was exactly what Tsitsipas needed to not pile onto the miles he ran against Fritz.
It was, in its way, as shocking a loss for Sinner as it was a surprisingly easy win for Tsitsipas.
But it was also clear that the No. 4 seed has played his way into the tournament. And that he will give Medvedev – who won’t be nearly as fresh – all he can handle.
Despite Medvedev’s favorite status, we’re calling for an upset in this one.
Best Bet: Tsitsipas wins, and both players take a set (+300)
Sports Writer
Stephanie gets the straight dope from the tennis insiders. On court, she has represented her country internationally. A BA in journalism led to years on the MLB beat and a decade covering tennis globally. She's written for Postmedia, the Guardian, the New York Times and also publishes OpenCourt.ca.