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Diamondbacks vs Cubs Odds and Picks (May 21)

John Perrotto

by John Perrotto in MLB Baseball

May 20, 2022 · 6:41 PM PDT

Josh Rojas dugout celebration
May 20, 2022; Chicago, Illinois, USA; Arizona Diamondbacks third baseman Josh Rojas (10) celebrates ninth dugout after he hit a two run home run against the Chicago Cubs during the fifth inning at Wrigley Field. Mandatory Credit: Matt Marton-USA TODAY Sports
  • The Cubs are -150 home favorites over the Diamondbacks on Saturday
  • Justin Steele (1-4, 4.50) will start for Chicago against fellow lefty Madison Bumgarner (2-2, 2.29)
  • A look at the matchup and odds can be found below with a pick

The Arizona Diamondbacks will try to make it three in a row against the host Chicago Cubs when the teams meet at 2:20pm ET Saturday at Wrigley Field.

The Diamondbacks (20-21, 10-10 road) have won the first two games of the four-game series, including 10-6 on Friday, after coming into Chicago on a six-game losing streak. The Cubs (15-23, 6-14 home) have lost three games in a row.

Diamondbacks vs Cubs Odds

Team Moneyline Runline Total
Arizona Diamondbacks +125 OFF OFF
Chicago Cubs -150 OFF OFF

Odds as of May 20th at BetMGM





The Cubs are -150 favorites, giving them a 60% expected win probability. Both teams have long World Series odds as the Cubs are listed at +35000 and the Diamondbacks at +60000.

The weather forecast calls for a chilly and rainy afternoon in Wrigleyville with the temperature 52 degrees at gametime, and northwest winds from 5-15 mph and gusts up to 20 mph. There is an 80% chance of showers and possible thunderstorms.

Probable Pitchers

In a matchup of left-handers, the Diamondbacks’ Madison Bumgarner (2-2, 2.29) will face Justin Steele (1-4, 4.50). Bumgarner will be pitching on four days of rest and Steele on five.

Bumgarner vs Steele

Madison Bumgarner
Justin Steele
2-2 Record 1-4
2.29 ERA 4.50
3.94 xERA 3.20
1.19 WHIP 1.57
1.50 SO/W 1.93

Bumgarner had a no-decision against the Dodgers on Monday in Los Angeles, allowing three runs and six hits in five innings with two walks and a strikeout.

Against the Cubs, Bumgarner has a 9-3 career record and 2.40 ERA in 16 starts. He is 4-2 with a 3.44 ERA in six starts at Wrigley Field.

This, of course, is Bumgarner’s most memorable moment of 2022.

Bumgarner is 1-2 with a 2.81 ERA in four road starts this season and 0-1 despite a sparkling 0.82 ERA in three days games.

Jonathan Villar is 5-for-7 against Bumgarner with two doubles and a home run. Conversely, Ian Happ is 0_for-5.

Steele is 0-4 in his last six starts since beating the Milwaukee Brewers on April 9 in his season debut.

However, Steele pitched well against the Diamondbacks last Sunday in Phoenix despite not factoring in the decision. He worked six innings and gave up two runs (one earned), three hits and two walks while striking out a career-high 10.

That was Steele’s first career start against the Diamondbacks.

Steele is 1-3 with a 5.52 ERA at home in four starts this season. In the day, he has a 1-1 record and a 2.57 ERFA in three starts.

Diamondbacks vs Cubs Betting Outlook

Josh Rojas hit his first three home runs of the season – in a game that had 11 total longballs – to power the Diamondbacks to victory Friday.

Rojas began the season on the injured list with a strained right oblique before being activated May 6. He had solo homers in the third and seventh innings and a two-run blast in the fifth.

David Peralta added two home runs for the Diamondbacks, while Alek Thomas. Christian Walker hit solo shots.

Villar doubled and homered for the Cubs while playing in his 1,000th career game. Rookie Christian Morel hit his first major league home run and Patrick Wisdom and Ildemaro Vargas also connected.

Arizona recalled outfielder Jake McCarthy from Triple-A Reno before the game, and he had two hits and two RBIs. Ketel Marte (hand) sat out for the third time in four games but is expected to play Saturday.

Shortstop Andrelton Simmons and right fielder Seiya Suzuki, who has +6000 NL MVP odds, are expected to play after being rested Friday.

The Diamondbacks have won three of five games against the Cubs this year, but Chicago has a 26-17 edge in the series since the start of the 2015 season.

Diamondbacks vs Cubs Last 10 Games

Date Home Team Away Team Score
5/20/22 Cubs Diamondbacks ARI, 10-6
5/19/22 Cubs Diamondbacks ARI, 3-1
5/15/22 Diamondbacks Cubs CHC, 3-2
5/14/22 Diamondbacks Cubs CHC, 4-2
5/13/22 Diamondbacks Cubs ARI, 5-4
7/25/21 Cubs Diamondbacks CHC, 5-1
7/24/21 Cubs Diamondbacks ARI, 7-3
7/23/21 Cubs Diamondbacks CHC, 8-3
7/18/21 Diamondbacks Cubs ARI, 6-4
7/17/21 Diamondbacks Cubs CHC, 4-2

Diamondbacks vs Cubs Prediction

The moneyline seems a bit high considering Bumgarner is pitching for the Diamondbacks. However, the Cubs are the way to go after the way Steele dominated Arizona last weekend.

Pick: Cubs ML (-150)

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