Upcoming Match-ups

White Sox vs Pirates Predictions & Odds (April 7)

John Perrotto

by John Perrotto in MLB Baseball

Updated Apr 6, 2023 · 8:45 PM PDT

Chicago White Sox starting pitcher Lucas Giolito on the mound
Apr 1, 2023; Houston, Texas, USA; Chicago White Sox starting pitcher Lucas Giolito (27) pitches against the Houston Astros in the first inning at Minute Maid Park. Mandatory Credit: Thomas Shea-USA TODAY Sports
  • The White Sox are -140 road favorites over the Pirates on Friday
  • Lucas Giolito (0-0, 3.60) will start for the White Sox against Pirates lefty Rich Hill (0-1, 5.40)
  • A look at the White Sox vs Pirates odds and picks can be found below

The Pittsburgh Pirates play their home opener when they meet the Chicago White Sox at 4:12 p.m. ET Friday at PNC Park.

The Pirates (4-2, 0-0 home) are coming off a three-game series sweep of the Red Sox in Boston, including a 4-1 win on Wednesday. The White Sox (3-4, 2-2 road) were pounded by the San Francisco Giants 16-6 on Thursday at home for their second loss in the last three games.

MLB Network will televise the game.

White Sox vs Pirates Odds

Team Moneyline Runline Total
Chicago White Sox -140 -1.5 (+125) Over 8.5 (+100)
Pittsburgh Pirates +120 +1.5 (-145) Under 8.5 (-120)

The Chicago White Sox are -140 road favorites over the Pirates on the moneyline in the MLB odds, giving them a 58.33% implied win probability. Chicago is listed at +4000 in the World Series championship odds and Pittsburgh at +25000.

The high temperature is expected to be 56 with sunny skies and a northwest wind at 8-10 mph.



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Odds as of April 6th at DraftKings Sportsbook.

White Sox vs Pirates Probable Pitchers

Lucas Giolito (0-0, 3.60) is expected to start for the White Sox against left-hander Rich Hill (0-1, 5.40). Both will be pitching on five days of rest.

Giolito vs Hill

Lucas Giolito
Rich Hill
0-0 Record 0-1
3.60 ERA 5.40
2.91 xERA 5.47
1.20 WHIP 1.00
6.00 SO/W 3.50

Giolito had a no-decision in his first start of the season last Saturday against the Astros in Houston. He worked five innings and gave up three runs (two earned) on three hits while striking out six and walking one.

Giolito is 1-0 with a 3.09 ERA in four starts against the Pirates in his career. The win was a no-hitter during the pandemic-shortened 2020 season in Chicago.

In day games, Giolito has a 3.83 career ERA as opposed to 4.59 at night. Giolito’s ERA on the road is also more than a full run better than at home – 3.67 to 4.99.

Giolito’s AL Cy Young Award odds are +5000.

Hill, the oldest player in the major leagues at 43, lost his Pirates’ debut last Saturday against the Reds in Cincinnati. He gave up three runs and three hits over five innings with seven strikeouts and two walks.

Hill has never beaten the White Sox in 19 career games (five starts), going 0-3 with a 5.79 ERA.

Throughout his 19-year career, Hill has maintained minimal splits with a 3.80 ERA in home games to 3.90 on the road and 3.79 during the day to 3.89 at night. He has a 4.20 ERA in five career starts at PNC Park.

Batting Average vs Starting Pitchers

White Sox Batters Batting Average vs Rich Hill
Jake Burger .500
Elvis Andrus .091
Andrew Benintendi .000
Tim Anderson .000
Hanser Alberto .000
Yoan Moncada .000
Luis Robert Jr. .000
Andrew Vaughn .000
Pirates Batters Batting Average vs Lucas Giolito
Bryan Reynolds .250
Ji-Man Choi .214
Carlos Santana .191
Ke’Bryan Hayes .000

All White Sox hitters are a combined 2 for 31 (.065) against Hill. Second baseman Elvis Andrus is 1 for 11 (.091) and left fielder Andrew Benintendi is hitless in seven at-bats.

Pirates first baseman Carlos Santana is 4 for 21 (.190) versus Giolito but has one home run and six walks.

White Sox vs Pirates Betting Outlook

Andrus had two hits, including a two-run double, to provide one of the few highlights for the White Sox in Thursday’s loss to the Giants. Hanser Alberto also had two hits and Tim Anderson drove in two runs.

Third baseman Yoan Moncada sat out with a sore foot but is expected to play Friday. He was injured Wednesday when he fouled a ball off his foot.

Santana hit a solo home run and an RBI double to lead the Pirates past the Red Sox on Wednesday. Andrew McCutchen also had two hits.

Shortstop Oneil Cruz is questionable for Friday after leaving the game with a facial injury. He got hurt when he slid into Red Sox third baseman Rafael Devers.

White Sox vs Pirates Last 10 Games

Date Home Team Away Team Score
9/1/21 White Sox Pirates CWS 6-3
8/31/21 White Sox Pirates CWS, 4-2
6/23/21 Pirates White Sox CWS, 4-3
6/22/21 Pirates White Sox PIT, 6-3
9/9/20 Pirates White Sox CWS, 8-1
9/8/20 Pirates White Sox PIT, 5-4
8/26/20 White Sox Pirates CWS, 10-3
8/25/20 White Sox Pirates CWS, 4-0
5/16/18 Pirates White Sox PIT, 3-2
5/15/18 Pirates White Sox PIT, 7-0

The White Sox have gone 6-2 against the Pirates since 2020 after Pittsburgh won eight games in a row in the series.

White Sox vs Pirates Prediction

While Hill has never beaten the White Sox in his long career, he has had plenty of success against their current hitters. That makes the Pirates a live dog here coming off the sweep in Boston and playing in their home opener.

Pick: Pirates +120 ML

Season Record: 4-1 (+2.6 units) ML


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