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Ohio State vs Northwestern Odds, Spread and Picks

Robert Duff

by Robert Duff in College Football

Nov 2, 2022 · 9:00 AM PDT

Ohio State vs Northwestern Odds, Spread and Picks
Oct 29, 2022; University Park, Pennsylvania, USA; Ohio State Buckeyes quarterback C.J. Stroud (7) calls out a play during the first half of the NCAA Division I football game against the Penn State Nittany Lions at Beaver Stadium. Mandatory Credit: Adam Cairns-The Columbus Dispatch Ncaa Football Ohio State Buckeyes At Penn State Nittany Lions
  • As far as the Ohio State vs Northwestern odds go, it’s the #2-ranked Buckeyes who are set as 38.5-point road favorites over the Wildcats on Saturday, November 5
  • Ohio State is 4-1-1 against the spread in the last six games
  • The Buckeyes are 18-1 straight up at Northwestern since 1961

When it comes to lopsided series, the dominance of the Ohio State Buckeyes (8-0, 4-3-1 ATS) over the Northwestern Wildcats (1-7, 3-5 ATS) is right up there among the most impressive.

Ohio State is 9-0 straight up against Northwestern. The Wildcats haven’t beaten the Buckeyes since 2004.

Since 1972, the Buckeyes hold a 33-1 SU edge over the Wildcats. At Northwestern, where this week’s game is being contested, Ohio State has won 18 of 19 games since 1958 and 22 of 24 contests since 1950.

In this encounter, the Buckeyes are set as 38.5-point road favorites. Ohio State is 7-2 ATS in the last nine games against Northwestern.

Ohio State vs Northwestern Odds

Team Spread Total Moneyline
Ohio State Buckeyes -38.5 (-110) O 60.5 (-110) -10000
Northwestern Wildcats +38.5 (-110) U 60.5 (-110) +2500

Odds as of November 2 at BetMGM Sportsbook. See the available BetMGM Sportsbook bonus code here.


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Northwestern is 0-7 SU in the past seven games and 3-8 ATS over the last 11 games. The total has gone over in six of the past eight games between the Buckeyes and Wildcats.

The kickoff for this game at Ryan Field is set for 12:00 pm ET on Saturday, November 5. The weather forecast is calling for rain, 24 mph wind and a temperature of 14 degrees. The broadcast of the game can be seen on ABC.

Buckeyes vs Wildcats Betting Trends

At moneyline odds of -10000, the Buckeyes are offering an implied probability of victory of 99.01% in the CFB odds. A successful $10 wager on Ohio State would return a payout of just $10.10.

In terms of NCAA public betting trends, the public isn’t batting an eye at laying 38.5 points on the Buckeyes. On the spread, Ohio State is getting the backing of 93% of handle and 80% of bets. Since most books aren’t posting a moneyline, there are no public moneyline splits. When it comes to the total of 60.5 points, there’s 62% of the handle on the under and 74% of bets supporting the over.

NCAA future book wagering is showing #2 Ohio State as the +190 chalk in the National Championship odds. Bettors can also get -650 odds on the Buckeyes making the College Football Playoff. Ohio State is also the -450 odds-on favorite to win the Big Ten Conference title.

Buckeyes Have It All Going On

If the CFP were to be starting today, Ohio State would qualify as the #2 seed. There’s not much that the Buckeyes don’t do well.

Ohio State is the NCAA’s #2 red zone offense (.976).  The Buckeyes are sixth in the nation in passing yards per completion (14.69). They’re #6 in total defense (270.1 yards per game).

Individually, quarterback CJ Stroud, the +150 second choice in the Heisman Trophy odds, shares the NCAA lead with 29 touchdown passes. He’s passed for 2,377 yards, good for 12th in the nation.

Sophomore wideout Marvin Harrison Jr has caught 10 of those TD receptions, putting him second in the nation. With seven TD catches, Emeka Egbuka ranks 11th in the NCAA. Running back Miyan Williams is fourth in the nation in yards per carry (6.91).

Wildcats Winless On American Soil

Entering Week 9 of the college football season, Northwestern is still seeking out the school’s first win of the campaign on US soil. The Wildcats opened the season with a victory over Nebraska in Dublin, Ireland. They’re 0-7 since returning to their homeland. A loss in this game and they will match their longest losing streak since 1993.

Northwestern QBs Ryan Hilinksi and Brendan Sullivan have combined to throw nine interceptions. Iowa, the #128 offense among 131 FBS schools, put up 33 points last week on the Wildcats.

Northwestern has given up at least 31 points in each of the past three games. Netting 17.9 points per game, the Wildcats rank 120th in the NCAA in scoring offense.

Ohio State vs Northwestern Prediction

The last five times that Northwestern has played host to Ohio State, the total has gone over. The Buckeyes have topped 40 points in seven of the last nine games between the two schools.

Ohio State is 5-3-1 ATS in the last nine games as a favorite of 20+ points over Northwestern. The Buckeyes are 2-1-1 ATS this season as a favorite of 30+ points.

Pick: Northwestern Wildcats +38 (-110).


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