South Carolina vs Clemson Prediction, Pick & Odds – CFB Week 14

• #15 South Carolina travels to #12 Clemson for the Palmetto Bowl
• Clemson is favored by three points on Saturday, November 30
• See below for the latest South Carolina vs Clemson odds, picks, and prediction for CFB Week 14

Rivalry Week is here, and one of the biggest games of the weekend takes place at Clemson. The #12 Tigers host #15 South Carolina on Saturday, November 30. The Palmetto Bowl is scheduled to kick off at noon ET.

Clemson has dominated this rivalry of late as they have won eight of the last nine meetings. South Carolina’s last win in this series was in 2022 when the Gamecocks won at Clemson 31-30.

While neither team is a lock to make the CFP bracket with a win, both programs are looking to make their case that they belong. The winner of this game would need some help and more chaos to ensue to make the College Football Playoff, but both teams are still alive.

Will South Carolina beat Clemson on the road again or will the Tigers continue their domination over the Gamecocks? Keep reading for my picks and prediction for one of, if not the biggest Palmetto Bowl in history.

South Carolina vs Clemson Odds

The college football odds list Clemson as a three-point favorite over South Carolina on Saturday. South Carolina opened at +4.5 before being bet down to a field goal. The O/U is set at 49.5 and has not moved since the line opened last week.

Odds as of Friday, November 29 at BetMGM. Claim the best BetMGM promo code before placing your CFB Week 14 bets.

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South Carolina Betting Trends

South Carolina enters Rivalry Week as one of the hottest teams in college football. They have won five in a row, including big wins over Texas A&M and Missouri, and have covered the spread in five of their last six games. The Gamecocks are one of the best ATS teams in the country this season with an 8-3 record.

The Gamecocks can score. Led by quarterback LaNorris Sellers, they average over 400 yards per game and have scored at least 28 points in their last five games. In the last two games, Sellers has 659 passing yards, nine total touchdowns, and two interceptions. While their passing attack has improved of late, South Carolina has found more success on the ground. The Gamecocks are fourth in the SEC in rushing yards with 181.8 per game.

Eyes forward 🤙 pic.twitter.com/conWzrFuXe

— Gamecock Football (@GamecockFB) November 27, 2024

The offense has been great, but the defense is what has elevated this South Carolina team. They have allowed just 16 points per game this season and are third in the country in sacks. They will look to cause havoc against Clemson to round out the regular season.

Clemson Betting Trends

The Tigers are 9-2 straight up and 5-6 against the spread this season. Clemson has covered the spread just once in their last five games.

Clemson’s offense has been good with quarterback Cade Klubnik and running back Phil Mafah, but the defense has been great. Quarterbacks have struggled against the Tigers’ opportunistic defense. They have forced seven turnovers in the last three games and are third in the ACC in scoring defense.

On offense, Clemson is the epitome of a balanced attack. They rank 23rd in passing offense and 26th in rushing offense. They have had their way with the majority of the ACC opponents they have faced. Despite the balanced attack, the under has hit in three of Clemson’s last four games.

South Carolina vs Clemson Prediction

Both teams essentially had a bye week last week to prepare for this game as South Carolina beat Wofford 56-12 and Clemson beat The Citadel 51-14. This should be an exciting game, but I trust South Carolina much more in this spot.

Clemson’s offense has been productive, but they have not seen a defense as good as South Carolina’s since they played Georgia in their opener. Clemson’s whole schedule outside of Week 1 is worth questioning as well. They played an ACC schedule and avoided SMU and Miami. The best ACC team that they played was Louisville and they lost to them at home. I expect South Carolina’s front seven to cause fits for Clemson’s offense.

Clemson’s defense has been great against ACC competition, but they have been vulnerable on the ground. They are 10th in their conference in rushing yards allowed with 139.6 per game. The combination of Sellers and running back Raheim Sanders will be too much for Clemson.

South Carolina is a really good, complete team that was just a couple of plays away from beating LSU and Alabama which would have made them 10-1 heading into this game. I believe the wrong team is favored in the Palmetto Bowl this year, so I like getting three points with South Carolina on Saturday.

South Carolina vs Clemson Pick: South Carolina +3 (-110)