NFL Public Betting & Money Percentages for Chargers vs 49ers Sunday Night Football

By Robert Duff in NFL Football
Updated: March 16, 2023 at 12:40 pm EDTPublished:

- Moneyline bettors are strongly backing the San Francisco 49ers over the Los Angeles Chargers in the NFL public betting splits for Week 10 SNF
- ATS bettors, though, are leaning slightly toward the LAC in the Chargers vs 49ers public betting percentages
- Public bettors are also siding with the under in the Chargers vs 49ers Sunday Night Football game
As the Los Angeles Chargers (5-3, 5-3 ATS) and San Francisco 49ers (4-4, 4-4 ATS) get ready to clash in the Week 10 SNF game, NFL public moneyline bettors are moving heavily toward the 49ers. They’re obviously looking at the 7-0 run of success San Francisco is enjoying lately against teams from Los Angeles.
When it comes to the spread, the public betting and money percentages are tilting ever so slightly toward the Chargers. They’re probably looking that the fact that all of San Francisco’s LA success has come at the expense of the Rams. The 49ers are 0-5 straight up and 1-4 against the spread in their last five games against the Chargers.
Oddsmakers aren’t choosing remember the Niners’ history when facing the Chargers. San Francisco is a 7.5-point home favorite in the Week 10 NFL odds.
Chargers vs 49ers Public Betting Splits
Game | Spread | ATS Handle % | ATS Bet % | Total | O/U Handle % | O/U Bet % | Moneyline | ML Handle % | ML Bet % |
---|---|---|---|---|---|---|---|---|---|
Los Angeles Chargers | -7.5 | 54% | 55% | O 45 | 34% | 59% | +265 | 29% | 19% |
San Francisco 49ers | +7.5 | 46% | 45% | U 45 | 66% | 41% | -320 | 71% | 81% |
Betting splits from DraftKings Sportsbook. Get this DraftKings promo code to bet on tonight’s SNF game.
The Chargers vs 49ers public betting picks are showing division the over on the total of 46 points. There’s 66% of the handle going with the under, while 59% of bets are supporting the over.

Kickoff at Levi’s Stadium is set for 8:20 pm ET on Sunday, November 13. The weather forecast is calling for rain, 10 mph wind and a temperature of 81 degrees. The game is airing on NBC in the USA and DAZN in Canada.
Public Spread Bettors Liking Underdog Chargers
The 49ers were the 7-point home chalk in the NFL Week 10 opening odds for this game. The public action moved the line to San Francisco -7.5. Going with the Chargers in the Chargers vs 49ers picks is certainly following a long-standing trend.
You have to go all the way back to 2000 to find a 49ers victory over the Chargers. In terms of the spread, San Francisco did cover in the last meeting between the two teams. Even though the Chargers won outright 29-27, it was the 49ers who were the ATS winners as 10-point underdogs. That was also the first meeting between the two teams since the Chargers relocated from San Diego to LA.
The Chargers were 5-1 ATS in the previous six games, so perhaps there is something to the San Francisco success against teams from Los Angeles.
GAME DAY 💪🏽 Let’s get it. #SNF ⚡️ pic.twitter.com/JSLf9laUsO
— Austin Ekeler (@AustinEkeler) November 13, 2022
In the public spread betting splits, the Chargers are drawing 54% of handle and 55% of bets. Los Angeles is 4-0 ATS on the road this season.
However, San Francisco is 6-1 ATS over the club’s last seven home games. Through the past 20 games, San Fran is 14-6 ATS.
Public at Total Opposites on Over/Under
If you’re looking at San Francisco games, then the public handle support for the under is understandable. The 49ers have gone under in 12 of their past 16 games.
However, looking at the action between the 49ers and Chargers, then the 59% of public bets backing the over also makes sense. In this rivalry, eight of the last 11 Chargers vs 49ers games have gone over.
In terms of the Chargers, they’ve gone over in 10 of their past 14 games. As well, the over is 7-1 in LA’s last eight games when facing an opponent from the NFC West division.
Moneyline Bettors Overwhelmingly With 49ers
The Chargers have won their last two visits to San Francisco by a combined margin of 88-54. San Francisco hasn’t won at home against the Chargers since 1997.
Will be interesting to see how the 49ers leverage the post-bye energy boost. I thought the Rams had one versus them, hence LA's solid start, but SF shut it down in due time.
But we should see a very fresh and healthy 49ers team vs the Chargers on SNF. That's the vibe in building
— David Lombardi (@LombardiHimself) November 9, 2022
San Francisco are -300 odds-on favorites to make in in the NFL playoff odds. The Chargers are the +475 second betting choice to take the AFC West in the NFL Divisional odds.
LA is 4-1 SU over the team’s past five games. San Francisco is 13-7 SU over the past 20 games. The 49ers are 6-1 SU through their past seven home games. However, San Fran’s only home loss this season was to an AFC West squad, the Kansas City Chiefs.


Sports Writer
An industry veteran, Bob literally taught the course on the history of sports at Elder College. He has worked as a Sports Columnist for Postmedia, appeared as a guest on several radio stations, was the Vice President of the Society For International Hockey Research in Ontario, and written 25 books.